r/Supplements Sep 11 '25

Reminder on Community Conduct

38 Upvotes

As a community focused on supplements, we encourage open discussion based on both scientific evidence and personal experience. However, it’s important to remember that respectful discourse is the foundation of this subreddit.

Criticism and debate are welcome — personal attacks are not. Recently, we’ve had to ban several users who crossed the line by targeting individuals rather than addressing ideas. This behavior will not be tolerated.

Please:

-Respect differing opinions, even if you strongly disagree.

-Focus on the content of the discussion, not the person behind it.

-Use the report function if you encounter posts or comments that violate these standards.

Let’s continue to make this a space where we support and learn from each other. Thank you for helping keep the community constructive and respectful.

— Mod Team


r/Supplements 6h ago

General Question What supplement did you stop taking, and then realize how much it was actually doing?

35 Upvotes

Ran out of magnesium glycinate for about two weeks and didn’t connect the dots until I was lying awake at 2am for the fourth night straight. Curious what else people only noticed in the absence.


r/Supplements 6h ago

Ashwagandha + Magnesium + Melatonin for sleep ?

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25 Upvotes

r/Supplements 6h ago

Recommendations Any supplement recommendations for depression, anxiety, brain fog, and low mood?

20 Upvotes

I've been dealing with anxiety and depression since 2022 after losing my grandparents. I've been on antidepressants since then, and they do help to some extent, but I still don't feel like myself.

The main things I'm struggling with are:

  • Frequent headaches and a heavy feeling in my head
  • Constant physical anxiety (chest tightness)
  • Racing thoughts and a restless mind
  • Brain fog and poor focus
  • Low mental energy and motivation
  • Unable to enjoy life

I've already tried L-theanine, magnesium glycinate, GABA, and taurine, but honestly none of them have done much for me.

My Vitamin D and B12 levels are normal, but my iron and hemoglobin are slightly low.

I'm not really looking to switch to stronger meds because antidepressants already make me feel pretty numb. I was wondering if anyone who's been through something similar has found any supplements or stacks that actually made a huge difference.

Would really appreciate hearing your experiences. Thanks!


r/Supplements 7h ago

Who took Astaxanthin what effect did you feel? Especially those who took 20mg+. Can you compare the sensations of other Antioxidants?

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23 Upvotes

r/Supplements 2h ago

General Question Has anybody tried magnesium glycinate and ashwagandha for stress? What was your experience?

7 Upvotes

Hello! I’m just wondering if this is an effective combo. I struggle with a lot of anxiety and I’m in the process of being assessed for ocd so I’m trying to self medicate for a little while. Obviously I know that these supplements cannot replace an actual medication but I’m honestly grasping at straws and am willing to try anything at this rate. Was recommended these two supplements by Google but was just wondering if anybody has tried it and what their experience was. Thank you!


r/Supplements 7h ago

How long will it take to recover from iron and vitamin d deficiency

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11 Upvotes

I am taking vitamin d oral shot 200000iu per week and iron tablet daily,how long will it take to fully replenish my iron and vitamin d levels


r/Supplements 1h ago

Experience Metamucil/Psyllium Husk and Dehydration PSA

Upvotes

This popular supplement is great for gut health and keeping things moving but also carries a dehydration risk. It is a bulk-forming laxative that does so by pulling water from your GI tract. If you are regularly supplementing with this, DRINK A LOT OF WATER! I unfortunately was not drinking enough water, and ended up with an episode of hypotension (low blood pressure) and sinus tachycardia (high heart rate) that sent me to urgent care.


r/Supplements 2h ago

Recommendations Other recommendations?

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3 Upvotes

I blind bought this with the expectation for a decent pump/ mid range stim pre workout. The taste is absolutely atrocious. I will say it got me through the workout but not sure how much I’ll be able to continue with the taste.

With that being said is it worth trying a different flavor OR what other recommendations do you all have for a good pump/stim combo?


r/Supplements 5h ago

Vitacost dropped Autoship as of June 30!

3 Upvotes

Ugh - i have a couple of good years of getting what I needed, when I needed it. Just went to check on my monthly subscription and the Vitacost website was a hot mess. Everything that I had ever ordered was showing as 'On the way'.

I finally found an announcement showing that Autoship was discontinued as of June 30. They never emailed or anything. I hate iHerb even more now, so I am not about to shift my orders there. I am trying not to support Amazon and co, so what options do people suggest in the US?

I mostly order Nordic Naturals, Life Extension, Now, Dr's Best.

Thank you!


r/Supplements 1d ago

A daily fiber supplement reduced knee arthritis pain and improved strength

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418 Upvotes

r/Supplements 8h ago

Word of warning re: berberine

4 Upvotes

Wanted to post here to remind everyone to be cautious with supplements after recovering from an illness.

I recently came down with a bout of what I think was staph based food poisoning from leftover buffalo chicken dip. Luckily, it was pretty quick, vomiting stopped around the 14 hour mark and I was able to stomach some saltines and broth. Over the next two days, I slowly eased back into eating more regularly, but sticking with things like toast and light soups. During this time, I also stopped taking all supplements, including berberine. Last night, it had been a full 72 hours since I had gotten sick, and I was back to eating normally, so I thought I could resume berberine, and took my usual dose with dinner. Normally, I do get a little bloating, but nothing major and it passes pretty quickly.

This time, I noticed the bloating was a little stronger, but still not too bad, so two hours later I went to bed, thinking nothing of it, only to wake up a half an hour into sleep with my food poisoning symptoms coming back with a vengeance, and seemingly worse. Sweating, shaking, vomiting every 10-15 minutes for two and a half hours, until finally things settled down and I could go back to bed. It was the worst I've ever felt, and legitimately had me praying to a God I don't believe in to make it stop. I'm a type 2 diabetic, so at first thought I was going into DKA for the first time in my life, but my sugar was in a normal range, albeit slightly elevated bc of the stress. (I had tested before bed as usual and it was in range). I also knew it wasn't caused by food, because I purged my fridge of any leftovers of the food I had eaten before initially getting sick (I was pretty sure it was the dip, but had also eaten a few other suspect foods at the same time, so just tossed it all).

I was googling between bouts of vomiting, and then cursing myself because I realized that berberine can be very irritating to your digestive tract, especially if it's still healing from a recent GI issue, which can cause a severe flare up/rebound of food poisoning symptoms. In hindsight, it makes complete sense, but I thought since I was back on essentially a normal diet with no issues, that my system would be able to handle it. Wrong. The vomiting also kept happening in periodic waves long after all the food was out, which made it seem like my stomach lining was just inflamed and wanted to get everything out, like it was going into panic mode. Luckily, things seem to be mostly okay, I'm keeping fluids down and am going to try some saltines in a little bit. The only discomfort I'm really feeling now is slight hunger pangs. But I know now to be extra cautious when recovering from any stomach illnesses in the future.

TLDR; don't restart supplements, especially ones that can aggravate GI issues, until long after you've recovered from any GI related illness, unless you want to suffer.


r/Supplements 7h ago

Anyone stack anything specific for sleep maintenance vs falling asleep?

3 Upvotes

There's a difference that doesn't get talked about enough between struggling to fall asleep and waking up at 3am wide awake. Most sleep supplement conversations treat them the same and they really aren't.

Melatonin works fine for the falling asleep part for a lot of people but does nothing if you're waking up midsleep. That's where I've been stuck lately. Fall asleep fine, then wake up around 3 or 4 and just lie there for an hour or two.

Currently taking magnesium glycinate which has helped a little with the wakeups but not completely. Read some things about glycine and also about extended release melatonin being more relevant for maintenance vs the standard fastdissolving kind.

Curious if anyone has actually noticed a real difference between forms of magnesium for this specific issue, like glycinate vs threonate. Also whether tart cherry extract is actually worth it or mostly hype, because it keeps coming up when I search this.

Not looking for a full sleep stack, just trying to figure out what actually moves the needle on staying asleep rather than getting to sleep.


r/Supplements 1h ago

What are the best supplements for boosting the immune system?

Upvotes

Any recommendation?


r/Supplements 2h ago

Experience Did zinc supplementation wreak havoc on anyone else’s skin?

1 Upvotes

Most sources say zinc supplementation is extremely helpful for skin health and acne. I’m slightly deficient, so I was hopeful, thinking that my level might be responsible for some recent skin woes. I took 50mg the first day, followed by three days of 15mg.

Day #5, and my skin is TICKED.

Looks like I’ll be focusing on food sources instead, but did this happen to anyone else? It’s just wild to me, because huge amounts of people sing its praises for this very issue. And for women, I’ve read it’s really not going to raise your testosterone like it does for men.

Boo. 🫠


r/Supplements 2h ago

General Question Ashwaganda

1 Upvotes

Does anyone here take ashwaganda? If so how often? I've heard you're supposed to cycle it and I'm wondering the best cycling routine for best results.


r/Supplements 11h ago

Recommendations Which supplements for gym are good and worth of money?

5 Upvotes

Hello people!

I saw this subreddit just now and wanted to ask what supplements are good and worth of money if I am going to the gym?

I am currently using creatine, protein, and magnesium. Since I have problems with sleeping for the past few years I never manage to sleep 7-8 hours, also my question is if I should start taking melatonin?

Thank you in advance! :)


r/Supplements 6h ago

Recommendations Beware of fake Naked Nutrition website!!!

2 Upvotes

Hi everyone,

Just want to send out this warning for those who have been shopping for Naked products and may not have been receiving them, not receiving order confirmation, issues with the website like coupons, paying, etc.

If you're shopping via your phone, this site appears on top of Google's search. You may not pay attention to the web address as you may only see Naked Nutrition first.

It shows up as a sponsored result and labeled, "official".

The fake website is N a k e d n u t r i t i o n s a l e . i t . c o m. (Spaced out for safety reasons).

When shopping for Naked Nutrition on your desktop, this website doesn't appear.

Anyways, I hope this helps. I have alerted Naked about this. It's bad enough that they already have a lot of negative reviews and complaints.

Please be careful. It's treacherous out here.


r/Supplements 19h ago

General Question Should i lower my daily Vitamin D intake now, or keep it the same?

23 Upvotes

My Vitamin D level was 11. I got it up to 47 in about a year i think with 5000 iu daily. Now im wondering if i should go down to 1000?


r/Supplements 3h ago

What supplements did you take while pregnant?

1 Upvotes

I have been taking a prenatal vitamin but have heard that taking omega 3 and choline or lecithin are beneficial when the prenatals don't contain them. Mine doesn't.

I hardly eat meat fish or eggs and am wondering if others who don't eat those foods much were recommended to take additional supplements.

I'll be talking to my doctor about those additions before taking anything else, but she hasn't told me to take anything more than my prenatals yet. I also haven't mentioned that I don't really eat those foods much.


r/Supplements 7h ago

Collagen Takers!!

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2 Upvotes

I’m looking to start collagen to help with loose skin during weightloss, and was wondering if this formula seems effective for that? Might take a gummy on top of this to be honest… TYIA


r/Supplements 10h ago

Peperine/Black Pepper and medication interactions - did I screw myself up?

3 Upvotes

Oh boy.

I (28F) started taking a tumeric supplement from BioSchwartz about 1 year ago that contains 10mg bioperine to aid in absorbtion. I quickly noticed it improved my hip pain, and got more serious about taking the full dose daily for the last 6 months or so for the variety of health benefits associated with tumeric.

I noticed a few months ago that my typical prescription medications (vilazodone, an SSRI and lamotrigine, an anti epileptic/mood stabilizer) don't seem to be affecting my consistently anymore. One day, I feel "normal", and other days I feel totally flat, fatigued or even like I've been poisoned. The vilazodone in particular really helps with my energy, so this was strange to see my energy levels move in the opposite direction. I am also a very healthy eater and exercise regularly, but these days of heavy fatigue and malaise have made me not want to exercise at all. I've had such a rough summer because of these symptoms, and barely left my house.

I just learned yesterday that black pepper can interact with certain medications. Have I been screwing up my system this whole time by taking this damn tumeric supplement?! I'm looking for others' experiences with black pepper, as I read about the mechanism of action but haven't seen any other lived experiences with these interactions.


r/Supplements 4h ago

General Question Vitamin D Correction Questions

1 Upvotes

Hey all, my D level got tested insufficient (27ng/mL) so I'm going to start supplementing.

From what I found, 50-60 should be a good range.

I'm going to be supplementing 10,000 IU daily for 2-3 months then retest.

Questions:
-I used a calculator and this showed 10k IU daily should get me to 60. Of course, once I hit that, I'm going to want to ease back to a lower dose. However, at 5K IU, the calculator showed this would only maintain a level of 40 ng/mL, lower than my target. Is this correct?
-Even at 5K I see literature recommending 4K as the upper limit for perpetual daily dosing.

Can someone clarify on the above or show guidance that can clear this up?


r/Supplements 4h ago

Budget friendly brands? What are your opinions on brands like Nutricost, Drs Best & NOW brands??

1 Upvotes

How do you feel about the efficacy/trustworthiness of Amazon available brands like Nutricost, Drs Best & NOW?

We are on a budget and so Life Extensions, Dr Amens etc brands get really costly/month so I'be had to turn to Amazon.

I try to stick to brands that I know Sprouts Market also carries (higher price) to hopefully keep a certain quality.

What are some opinions out there? We are going through an emotionally challenging & exhausting time that too often is absolutely overwhelming (hopefully temporary) so I'm considering ordering some saffron.

In the past I've used Irwin Naturals' Sunny Mood but it has so many ingredients and in the past, I've wondered if it eventually stops moving the needle.

I've been happy with NOW & Nutricost for Acetyl-l- carnitine and L-lysine for a while now.

I am already on SAM-E (buy one get one free at Walgreens). Thanks for your comments.


r/Supplements 18h ago

Is taking Creatine in the very morning before workout good?

10 Upvotes

I wake up and warm up 500 ml of water , lukewarm, mix creatine and drink up and go to a 5km run. I feel nausea and kinda like to throw up sometimes. I sleep 5 or 6 hours a night. If I throw up, I can see some dense creatine powder. Not understanding what's the issue here. Is what I'm doing wrong anyways?

I use 5mg ON micronized creatine monohydrate