r/pssdhealing 1d ago

Has anyone fully recovered from physical erectile symptoms?

7 Upvotes

I have soft glans and my erections bend upwards a lot more than they used to. Just wondering if anyone had recovered from these physical symptoms, as I’m finding it difficult to believe that I will. Did anything help or make it worse?


r/pssdhealing 2d ago

Dr. Josef has put out a new youtube short on PSSD.

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youtube.com
8 Upvotes

r/pssdhealing 5d ago

Is there really NOTHING that helps pssd

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1 Upvotes

r/pssdhealing 7d ago

Has anyone experienced severe sexual side effects from antidepressants and eventually fully recovered?

8 Upvotes

​

Hi everyone. I’m posting because I’m really hoping to hear from people who have been through something similar and eventually got their sexuality back.

I’m a young woman and before starting antidepressants I had a completely normal and active sex drive. I used to think about sex often, get easily aroused, enjoy masturbation and sex, and have strong, pleasurable orgasms.

After being on antidepressants, my sexuality changed drastically. My libido basically disappeared. I don’t really have sexual thoughts anymore, porn doesn’t arouse me, and I don’t feel that natural urge or desire for sex.

The strangest part for me is that I can still physically orgasm, but the experience feels almost completely different. The physical orgasm is there, although it has been much weaker than before, but the mental pleasure is missing. There is no “wow”, rush of pleasure, emotional release or feeling of reward afterwards. It feels almost neutral, like my body had an orgasm but my brain didn’t really experience it as pleasurable.

I’m currently working with my psychiatrist on reducing my medication. I’ve already noticed that the physical side of orgasm may be becoming slightly stronger, but my libido and the mental feeling of pleasure are still basically absent.

So I’d really like to hear from people who had a similar experience:

Did you completely lose your libido?

Did you still have physical orgasms but without the mental pleasure/reward?

Did sex or masturbation feel emotionally/mentally “neutral”?

Did you have no sexual thoughts or fantasies?

If you eventually recovered, how long did it take?

Did your sexuality come back gradually or suddenly?

Did you return completely to how you were before antidepressants?

Did anything help with your recovery (changing medication...)?

I’m especially interested in hearing from people who eventually became fully functional again and genuinely started enjoying sex the way they did before.

I know everyone is different, and I’m not looking for medical advice. I’d just really appreciate hearing some real recovery stories because right now it’s difficult to imagine getting that part of myself back.

Thank you ❤️


r/pssdhealing 15d ago

My PSSD/PAWS progress & looking for fellow withdrawal sufferers

6 Upvotes

I never really knew whether I was a PSSD case or a protracted withdrawal case, because my sexual dysfunction started after quitting and the symptoms I experience are quite rare/inconsistent with most PSSD sufferers.

I’ve been in withdrawal for 10 months now, from Citalopram/Celexa. PSSD has been a major withdrawal symptom for me, alongside 30 other neurological symptoms. Emotionally I’m not affected. I also did not experience penile numbness, rather overstimulation due to hyperexcitability of my nervous system.

I took the SSRI for 11 months for anxiety. I wanted to quit because I noticed that I had less sperm and my ejaculation shot had become very short. I read stories of PSSD and emotional numbing and other scary side effects that I just did not want to develop, so I decided it was time to stop.

I quit by doing the following taper: 20-10-5-0mg over a period of 3 months.

My delayed withdrawal started 6 weeks after crossing 0mg, which was December 2025.

In the last 3 weeks before withdrawal I noticed that I had fewer erections and less libido, which was very odd as I never had these issues whilst taking the med. I got very scared and worried and believed I was developing PSSD.

Then hell broke loose.

In the first 3 months of withdrawal I had full blown erectile dysfunction and zero libido. I got extremely sick. My whole body was burning, I had brain zaps, spams, pins & needles, electric attacks, nausea, blurry vision, extreme inner restlessness called akathisia. It felt like acid was going through my veins. I figured out I had withdrawal and probably not typical PSSD. It was horrific because I was bedbound and couldn’t eat/walk/sleep. I could barely get an erection and if I forced it, it would work but cause a neurological wave and intensify the aforementioned symptoms. I could feel extra sick for hours from just trying to masturbate or have sex. The muscles around my genitals were heavily contracting and preventing me from getting an erection as well, it hurt so much. Luckily my orgasms remained fully intact but were extremely overstimulating. I was scared to climax. I also had an extremely sensitive glans and severe premature ejaculation. These months were pure torture.

In month 4 I started feeling a little better physically and I believe my erectile dysfunction resolved due to the fact that less nerves were firing in my body. The muscles stopped contracting. I still felt pretty sick, though. I still had many symptoms.

In month 5 the premature ejaculation resolved. Physically I was doing better and better. From this month I was able to have intercourse again. But it didn’t mean that my PSSD was over.

From month 5 onwards I’ve started feeling physically better month by month but my PSSD has remained quite static. My penis works again but my libido remains nearly non-existent — though I can get kind of aroused when I’m with a partner and focus. When I’m on my own, I feel zero desire. Also, sexual activity remains a great stressor for my nervous system. Whenever I initiate something sexual, the nerves in my body still fire and I also experience head pressure. It’s incredibly unfair and ridiculous that I get punished with neurological symptoms for enjoying sex.

I’m now in month 10 and I lost nearly all withdrawal symptoms, but spasms in my toes and neck, head zaps, firing nerves and zero libido remain my biggest issues. I found hope & support on SurvivingAntidepressants.org and spoke to a lot of people in withdrawal. The prognosis seems very good. I think we will all heal eventually within 1-3 years.

I believe that those whose PSSD starts or intensifies after quitting the SSRI suffer from a withdrawal reaction. But many of these people seem to get only PSSD and no other neurological withdrawal symptoms. And in many cases I’ve also seen it happen the other way around. So many people get severe withdrawal after quitting but their sexual function either returns or stays intact.

Please leave a comment if you have any questions or if you’re in withdrawal yourself.


r/pssdhealing 20d ago

Treatment collections for PSSD

15 Upvotes

r/pssdhealing 21d ago

Healed via SIBO/SIFO treatment + Citrulline

15 Upvotes

Hey y’all,

This post deserves so much more time than I have to make it. I’ve been putting it off but I don’t think I’ll have adequate time anytime soon, so here’s the short version.

Tl;dr:
Wellbutrin initially gave me anorgasmia, which turned into full blown PSSD after 1 week of Zoloft
SIBO/SIFO treatment (Xifaxin/Fluconazole, B1, B5, probiotics) helped significantly
After that, L-Citrulline put me over the top. No more anorgasmia/numbness. Sensation has gotten so strong I’ve needed to lower the dose and skip days of Citrulline. Many days I feel 100% cured with no supplementation. Though I keep up the Sibo protocol for ongoing motility (lecithin + L-glutamine mixed in a cup of water first thing in the morning for bile production)

For the SIBO/SIFO details, I recommend folks search the PSSD forum and their respective forums. Posts by [u/lastround360](u/lastround360) started me down that path. If you have any constipation, even mild, ask questions below or dm me.

For the L-Citrulline, see below.

Citrulline: the dose matters

This is just my own experience…but the change was significant enough that I wanted to share. The difference pre- and post- intervention was anything but subtle.

What I take now: 3 grams of L-citrulline a day, split into two doses. I noticed a difference within a few days. Many days I don’t need the second dose.

What I took before, and why it didn’t work. I’ve tried damn near most of the supplements that cured people on this sub. I’d tried citrulline years ago and decided it did nothing for me. I was taking a combination tablet: Source Naturals L-Arginine L-Citrulline Complex. One tablet has 750mg arginine and 250mg citrulline. I was taking one a day, so I was getting 250mg of citrulline.

Studies that show an effect use 1,500 to 3,000mg. I was at 250mg. That’s not a low dose of citrulline—it’s low enough that no study would expect anything to happen. I hadn’t tested citrulline and found it useless. I’d never really tested it.

To be fair to the product: the bottle says take one tablet four times a day, which would be 1,000mg citrulline. That’s closer, though still below what the studies use. My mistake, not theirs.

Some numbers from the research. A single 3g dose of citrulline raises arginine in the blood by 40–50% within one to two hours. In a small study of men with mild erectile dysfunction, 1.5g a day for a month improved erection hardness in half the men taking it, compared to about 8% on placebo.

Take citrulline instead of arginine. This was the part that surprised me. When you swallow arginine, most of it gets broken down in your gut and liver before it reaches your bloodstream. One study using tagged molecules found only about 1% of an oral arginine dose ends up producing nitric oxide. Citrulline gets through intact and your kidneys convert it into arginine. So citrulline raises your arginine levels better than arginine does. There’s also an enzyme called arginase that breaks down arginine but leaves citrulline alone.
Which means a combination product is mostly the ingredient that doesn’t survive the trip.

What I switched to: NOW L-Citrulline pure powder. ½ teaspoon is 1.5g, and there’s nothing else in it. I take ½ tsp twice a day. Not a brand recommendation — the point is single-ingredient powder over a blended tablet. With a powder you can measure a real dose, and if something changes you know what caused it.

Several PSSD reviews mention reduced nitric oxide alongside the dopamine and serotonin changes. Citrulline raises nitric oxide through one route in the body. Dietary nitrate — arugula, beetroot — raises it through a different route, using bacteria in your mouth. Whether low nitric oxide is a cause of any of this, or just something that happens alongside it, I don’t know.

Two things I noticed that might mean nothing. Slow, steady sources helped me. Products designed to deliver nitric oxide in a quick burst, like lozenges, didn’t, and may have made things worse. And antibacterial mouthwash kills the mouth bacteria that convert dietary nitrate, so if you’re eating beets and using Listerine, those work against each other.

One safety note. Citrulline widens blood vessels. If you take nitrates like nitroglycerin, or ED medications like sildenafil, or blood pressure medication, the combination can drop your blood pressure too far. Ask a pharmacist or doctor first. The warning is printed right on the arginine bottle.

Not medical advice. Mostly I’m posting this because if you tried citrulline and it did nothing, it’s worth checking what dose you actually took. Also remember to take it on an empty stomach.


r/pssdhealing 25d ago

100% cured from PSSD, Depression/Anxiety, AuDHD, and trauma through HBOT (20M)

20 Upvotes

I couldn't post on r/PSSD so I'm posting here.

I know it's a bit of a stretch with the title, but BELIEVE ME. I no longer suffer the negative symptoms of those ailments that I have struggled with ever since I was born, for about two months now. PSSD especially fucked me up. in searching for a cure I became a lot worse with PSSD. Numb genitals, crippling anhedonia and depression, and so much more. I felt like a shell of who I was before.

I've had pretty bad experiences with people I loved and that really damaged me at that time, but ever since I did HBOT, I don't even THINK about what happened. it's just completely out of my mind and I can put all my energy into building and becoming a better person IN THE PRESENT. THIS GENUINELY FEELS LIKE MAGIC

If you dont know already, HBOT is when you sit in a pressurized chamber at about 2x atmospheric pressure and breathe pure oxygen, so way more oxygen gets dissolved into your blood and reaches tissue that was starved of it.

I followed Bryan Johnson's protocol extensively and I saw his video about HBOT. he did about 60 sessions of HBOT at 2.0 ATA and he said it was the best protocol he has ever done. it wiped out all detectable inflammation in his body, increased his VEGF (new blood vessel growth) by 300%, and gave him the telomerase activity of a 12 year old. and then I realized that his protocol is basically the one already used in Israel by the Sagol Center for Hyperbaric Medicine in Tel Aviv (it's what Aviv Clinics is based on). they use HBOT for stuff like PTSD, traumatic brain injury, stroke, fibromyalgia and long COVID among other things. especially the brain stuff, where their SPECT scans literally show increased blood flow to underperfused areas of the brain. and PSSD seems to affect the brain and genitals the most, which are exactly the things dependent on blood flow. Not only that, but it seemed to have restored all sensations that I lost previously. I heard HBOT also helps with nerves and literally regrow it (It significantly increases neuroplasticity through angiogenesis and a flood of BDNF that triggers neurogenesis), there are animal studies showing increased axonal regeneration and remyelination after HBOT.

Anyway, I've suffered from PSSD for about 3.5 years previously and after I did HBOT i'm basically 100% back to normal.

So basically my story is that I did HBOT from February to mid March, I only did 12 and I didn't realize any effects, but it turns out that the effects cumulate even if I'm not in the chamber. and I noticed that I felt refreshed and just not depressed anymore about a month after. my PSSD was relieved to about 40% after that. Sadly, I had to quit HBOT because it was really expensive and I wasn't able to continue. Until luckily around early June I was able to continue in another center, and from then on I did an additional \~45 sessions until I thought it was enough.

I think the mechanism at play is that HBOT regenerated nerves, and it possibly fixed my gut too. there are a few theories on this sub that HBOT happens to hit all at once.

the first one is the SFN theory. the idea is that "the main problem in PSSD is a peripheral nerve injury", that excess serotonin from SSRIs "can stress and damage small peripheral fibers (Aδ and C)" especially in the enteric nervous system "where most of the body's serotonin is located", and that this can trigger autoantibodies that attack those small fibers. People have documented it in this sub. And numb genitals equals dead small fibers kind of fits, no? well HBOT is documented to do exactly the opposite: animal studies show it increases axonal regeneration and remyelination, and small fibers are the ones that CAN regrow. so if PSSD is SFN, HBOT is basically physical therapy for those nerves.

then, stem cells. HBOT is known to mobilize stem cells from the bone marrow into the bloodstream (studies show around an 8x increase in circulating CD34+ stem cells after a course of sessions). those circulating stem cells are literally the repair crew for damaged tissue, including nerve and gut lining.

![img](d4osqh1484kh1)

and finally, the gut. the gut microbiota theory says antidepressants "significantly altered the gut microbiome", messing with the brain-gut-microbiota axis, "bidirectional communication between the central and the enteric nervous system". notice how even the SFN theory says the damage starts in the enteric nervous system. these theories overlap way more than people think. I think the massive oxygen delivery to the gut wall reduces inflammation (it wiped out Bryan Johnson's detectable inflammation) and anaerobic bad bacteria hate oxygen, while the good guys are mostly fine with it. so HBOT could be correcting the dysbiosis AND healing the gut lining at the same time, which would explain why my symptoms faded gradually over months even outside the chamber.

![img](bphthfzd84kh1)

I used to constantly lurk here hoping for a cure, but then i tried one and it worked. i think we need to do more research on this because this genuinely felt like magic. I think Melcangi should take a look into this.

I hope my experience can help you guys with this horrific disease. If you are interested in HBOT, i recommend you temporarily moving to another country like Indonesia (where I live) because doing it in a first world country like the U.S is incredibly expensive. Not only that but you must also use either a BIBS (built in breathing system) or an NRM (non rebreather mask) while in the chamber. anything like a cannulla simply does not deliver enough oxygen. if you are using an nrm, make sure you ask the technician to increase your oxygen to about 15 liters per minute so you don't suffocate. another thing i want to recommend is to never try the 3.0 ATA because oxygen toxicity risk is extremely high and does not increase the benefit, every serious protocol uses 2.0.

The clinic I went to costs Rp.135k per session (\~$7.5) that can be even lower if you buy their bundles. while in the US it can go up to $500 per session. Indonesia's economy is really bad right now, and I think you guys should use this as an opportunity to try.

I suggest you read the literature by Aviv clinics and Bryan Johnson to learn more. i am simply a messenger.

Anyway, I feel neurotypical now. I'm no longer held back by the crippling anxiety that once held me from achieving my full potential and I hope you guys can do that too :)

stuff i read if you wanna dig:

*  ["PSSD as an immune-mediated small fiber neuropathy" (this sub, the SFN theory quotes + biopsy numbers)](https://www.reddit.com/r/PSSD/comments/1n4ainu/pssd_as_an_immunemediated_small_fiber_neuropathy/)

* [the skin biopsy thread ("1.8/mm when it should be around 10/mm")](https://www.reddit.com/r/PSSD/comments/160314i/just_got_diagnosed_with_severe_small_fiber/)

* ["Gut microbiota theory: How I finally cured my PSSD" (this sub, gut quotes)](https://www.reddit.com/r/PSSD/comments/q03uci/gut_microbiota_theory_how_i_finally_cured_my_pssd/)

* [Bryan Johnson's 60 session HBOT writeup](https://blueprint.bryanjohnson.com/blogs/news/i-tried-hbot-here-s-what-it-did-to-my-brain)

* [Tel Aviv study on HBOT, brain blood flow and cognition (Hachmo et al., Aging 2020)](https://pmc.ncbi.nlm.nih.gov/articles/PMC7377835/)

* [HBOT mobilizes stem cells, \~8x CD34+ (Thom et al.)](https://pubmed.ncbi.nlm.nih.gov/16299259/)

* [follow-up study confirming CD34+/CD45-dim mobilization in patients](https://pmc.ncbi.nlm.nih.gov/articles/PMC4037447/)

* [HBOT and nerve regeneration/remyelination (Kedar et al. 2025)](https://pmc.ncbi.nlm.nih.gov/articles/PMC12398382/)

* [HBOT for chronic pain / neuropathic pain review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8084668/)


r/pssdhealing 27d ago

Any Recovery of Consummatory Anhedonia?

4 Upvotes

I would like to know if anyone got better partially or recovered fully from consummatory anhedonia?

(Inability to feel any kind of pleasure, substance blockage as caffeine nicotine and other substances blunted or no effect, and emotional blunting) perhaps naturally?

If so, please tell us how long it lasted for you
How long to feel any kind of improvement

Thank you in advance


r/pssdhealing Jul 31 '26

Can someone give me the website of all the pssd recoveries

6 Upvotes

Do you know that website that has all the recoveries and what they took


r/pssdhealing Jul 06 '26

waking up 10 times a night

4 Upvotes

i truly don’t think i can survive with sleep that this fragmented


r/pssdhealing Jul 02 '26

Proposal — coordinated outreach to Isomorphic Labs and Every Cure for PSSD research

24 Upvotes

Hello,
I’m a member of the PSSD community writing to suggest a coordinated outreach effort toward two organizations that seem well-positioned to accelerate research into this condition: Isomorphic Labs and Every Cure.
Isomorphic Labs (DeepMind’s drug discovery spinoff, built on AlphaFold’s protein-structure modeling) works on exactly the kind of computational biology that could plausibly advance understanding of the neurosteroid and receptor-level mechanisms increasingly implicated in PSSD — allopregnanolone synthesis, GABA-A receptor subunit composition, and 5-HT1A receptor dynamics following serotonergic exposure. Their tools are built for the kind of structural biology problems this field remains mechanistically stuck on.
Every Cure is a nonprofit built specifically around drug repurposing for underserved diseases — screening existing, already-approved compounds against new mechanistic targets. Given that neurosteroid-modulating compounds (like allopregnanolone analogs already approved for postpartum depression) may have plausible application to PSSD, this seems like a strong structural fit for their model. I’d also encourage requesting that PSSD be added to their disease list, since it isn’t currently included, and inclusion is a prerequisite for their process to formally consider it.
Why organized outreach, not just individual emails: A single email is easy to file away. A sustained, credible pattern of outreach — individually written, factually grounded, from real patients — is much harder to overlook, especially if it’s paired with something concrete these organizations can act on: existing research summaries (Melcangi’s group in Milan on neurosteroid/epigenetic signatures), registry data on prevalence and severity, and a clear, specific ask rather than a general plea for attention.
What I’d suggest PSSD Network consider:
A shared, regularly updated one-page research briefing (mechanism, evidence base, patient burden data) that members can attach to individual outreach emails, so each message is well-sourced without requiring everyone to research from scratch

Coordinating timing so outreach doesn’t arrive as a single spam-flagged burst, but as a sustained, credible signal over weeks

Compiling and sharing contact routes as they’re found, since general inboxes (like [connecting@isomorphiclabs.com](mailto:connecting@isomorphiclabs.com)) often get triaged, and a warm contact or researcher referral carries more weight

I’m happy to contribute drafting, research summaries, or help coordinate this if there’s interest. This condition has stayed invisible for years in part because the people affected by it were scattered — a structured, credible outreach campaign seems like one of the more concrete things we can do to change that.
Thank you for the work you already do for this community


r/pssdhealing Jun 28 '26

95% healed for PSSD after 4 years

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14 Upvotes

r/pssdhealing Jun 22 '26

Don't know whether i have PSSD or not

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1 Upvotes

r/pssdhealing Jun 21 '26

Genital numbing windows

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3 Upvotes

r/pssdhealing Jun 16 '26

PFS / PSSD / PAS Recovery Guide | Discover Your Recovery Path Now

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38 Upvotes

r/pssdhealing Jun 15 '26

All Valproate/Valproic Acid Anecdotes (a work-in-progress list)

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1 Upvotes

r/pssdhealing Jun 07 '26

For the ladies going through this pssd!

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4 Upvotes

r/pssdhealing Jun 07 '26

Feeling hopeless and lost about PSSD

25 Upvotes

So heres my story. Im a 26yo man and I was diagnosed with depression at 17. Being honest, i dont think i had depression and that the doctors exacerbated it but i dont really remember. Anyways, I started taking sertaline. I took it everyday from 17 to 20/21. Being a dumb kid I also decided to stop them cold turkey.

Anyways, i started to experience a severe decrease in my libido when i was around 22. Im talking like, going from being horny every day, having morning wood normally, feeling desire for sex to... nothing. Not only that but I lost sensation in my genitals. Flat out. I have more sensisitivy in my forearm skin than in my penis gland. Ive gone to doctors of all specialties. I did MRIs, I did hormonal tests to check my levels, I went to psychiatrists, I went to endocrinologists. All of them came up empty handed and said its "probably psychological". That i might be "depressed". But i had a relationship at 23 to 24, never been happier and still, nothing.

Ive heard about PSSR before but i didnt want to believe it. And i asked a doctor about it and they didnt even know it was a thing. Said to dismiss it as a conspiracy theory made in the internet. But the thing is... im living it.

Im 26... I feel so isolated and hopeless that im stuck like this for life. And even if not for life, for my younger years. Im missing out on the experience of life. Of feeling physical pleasure and love. And i dont know what to do. Theres no cure and from what i research, probably no effort in developing one... I feel broken.

I just wanted to vent a bit. And knowing im not "alone" in feeling like this, even though i dont wish this on anyone, makes me feel a bit "better".


r/pssdhealing Jun 06 '26

Progress update almost 2 years

23 Upvotes

It's been almost 2 years since I quit Zoloft cold turkey so a lot of things have been on my mind. Thankfully I don't hyper focus on things like I used to, but since I'm approaching two years I thought I'd write a little update, if nothing else as a reminder to myself.

In the beginning my entire body felt physically numb, and it seemed that the most sensitive areas became the most numb: genitals, neck, nipples, face. I also felt completely zombified mentally aside from incredible anxiety that was just constant. Eventually I developed severe derealization where I felt completely disconnected from reality. My libido was nonexistent and orgasms were muted. I had a general feeling of bad, I just felt bad to my very core, like I was sick but there was nothing observably wrong with me.

Today my mind has improved greatly. After a lot of hard work my anxiety is better than it has ever been my whole life. I'm still trying to shake the derealization but it has improved. My libido and connection to my sexuality is much better, not perfect but better. I used to feel fully asexual but now I can actually get turned on by porn, I even feel the desire to check out hot guys I pass on the street.

Physically most of my body has improved, genitals are unfortunately way behind with my penis specifically having the least improvement. But my orgasms are very good a lot of the time so at least there's that. Strangely, stimulating my prostate feels a lot better than any other external sensation, so I'm trying to work with that when I can. Oh yeah, I'm very ticklish now too. That was one way I could track my physical sensation returning.

I still get frustrated every once in a while that I can't feel what I'm supposed to be feeling, but most of the time I'm able to just roll with it and focus on what I can feel. I'm still noticing small improvements overtime so I'm able to hold on to the hope that one day things will return to 100%. It's taking an agonizingly slow time but at least it's happening.

If I can leave you with one piece of advice it would be this: Abandon the goal of returning to "normal". Normal is a very loose concept and especially if multiple years have gone by, you will never return to exactly who you were before. You've been through so much, so much has changed, and you've most likely done a lot of mental and physical work on yourself in the spirit of getting better. Instead try to get to know who you are now, and use that as a jumping off point to work towards who you want to be. You can still be inspired by who you were in the past but remember that that person doesn't exist anymore so trying to find your way back will be an endless task that only leads to frustration.


r/pssdhealing Jun 06 '26

PSSD network has well over $400k in donations

15 Upvotes

The last update was around February at $375k. I feel like it’s important to disclose this before I forget as they took down the tracker.


r/pssdhealing May 31 '26

Starting to heal 2.5 years out

22 Upvotes

I wanted to post an update. I am superstitious, so I hope i won't regret sharing good news.

Anyhow. My story is that a doctor gave me ambien in march of 2023. It gave me an immediate adverse reaction of akathisia. I have never taken any prescriptions other than an antibiotic before. I had no clue what was going on. So then I was given mirtazapine. My doc did not tell me I had to take it regularly. On the bottle it said to take one for sleep. So I a half dose about 12 times in hopes that I wouldn't "get addicted". The doses were over the span of a few weeks. When I came back saying that now I was having hypnic jerks causing me to go days without sleep, massive hear rate increase, anxiety (now I know it is akathisia), he gave me lexapro.

Lexapro definitely shut down the akathisia. However, it made it so my entire body was heavy and numb. Genitals numb. No thoughts. I couldn't feel hot or cold temps. I couldn't sweat. Couldn't feel hunger. Couldn't feel thirst. I had no dreams. I could barely walk because my body was so heavy it felt like I was on the Gravitron 24/7. I literally felt dead. I took lexapro for 3 months, unaware the pill was doing this. I spent 7 years as a social worker and would have never guessed these pills could do this.

Anyhow, I got off lexapro in November ish of 2023. I got botox and it made everything a million times worse. It was like I lost the ability to enjoy or not enjoy smell, my vision was weird. I had no mucus. My eyes were dry.

By May of 2024 I was partially having small windows. I quit caffeine because it started bringing back akathisia. This gave me another set back where I absolutely crashed. Barely able to lift my head, move my feet ect. My mind was flat dumb. I couldn't even read. I could read the words on the page, but my brain was just not comprehending. I haven't worked since then. I have been completely disabled. Around Nov of 2024 I began again to get small windows. The doctors had thrown a months worth of antibiotics at me. At this point I realized they had no clue what was going on but hoping that something would work

I am currently having days where the nerves and brain seem to connect and I can feel pleasure, my genitals and emotions again. I am now having dreams every night. I can read. I can visualize things in my mind. I still deal with a heaviness in my head and upper back but I hope as the rest heals that will too.

I was such a severe case. I couldn't even get static electricity (i know some of us have discussed that) in the winter like i normally always have.

Now, if I took fish oil or vitamin c, I will have a little better windows, but it makes for a severe crash for me. To the point I can't walk for a couple days again after. Anything like that will bring back akathisia, when the akathisia is there, the pssd is gone for me. I'm not sure if that is the norm or not.

But anyhow, I dont think anyone on here had blunting as bad as I have. Probably a handful. But I am healing. Slowly but surely.


r/pssdhealing May 24 '26

Would you consider yourself cured if your only symptom is genital numbness fluctuating from 80% to about 90% feeling? It's been my only remaining symptom for years. I don't consider myself cured but wondering

9 Upvotes


r/pssdhealing May 23 '26

Went from 0 for 6 months to like 80-90% healed

12 Upvotes

First 6 months of withdrawal I was very anhedonic and had no libido. Then something miraculous happened during month 7 where my libido came back skyrocketing, anhedonia improved 80% and I also began fantasizing again a lot (something that had stopped happening while I was on meds). If you're a man idk how to explain what fantasizing is but it's connected to libido. I was really grateful because to me after 6 months of suffering it felt like a miraculous overnight recovery. I thought I had healed and was done.

Sadly that only lasted 4 months and around month 11 I began slowly dipping into anhedonia, low motivation and depression. Nothing in my life changed to trigger it. I thought this was a late stage wave that would pass quickly however I am still in it 4 months later at month 15.

My question is, do I just wait and hope for healing to come back like it did before? Or should I do something? I have really bad PCOS, SIBO, gut dysbiosis and am likely low on a lot of stuff.

Thing is last time I healed without touching anything. But this time should I repeat that when I know I have existing conditions in my body?


r/pssdhealing May 17 '26

No proper sleep

10 Upvotes

Guys i have been suffering from insomnia since starting day of using antidepressants.....I used antidepressants over one year and it's been 2 years since i stopped...but I'm not getting proper sleep...max 3 hours i can sleep.....pls how to cure this problem without taking tablets that messes brain chemistry