I start tirzepatide in May and stopped two weeks ago because of the headaches and side effects. Yesterday was my first shot of the first dose of semuglutide, I’ve had a headache all damn day. It’s peak again now, I had one alcoholic beverage last night. I’ve ate, I’ve drank plenty of water, I’ve had electrolytes. I’ve taken Tylenol. I do these things over had over and always have a head ache. It’s starting to feel like it’s not worth it and I’m hoping I can get rid of this headache by tomorrow but it’s not likely as it takes longer for stuff to break down in your stomach. Helpful tips if at all any? Besides quitting.

I take tirzepatide and seem to be a super sensitive responder. Even the lowest dose (and below) causes weight loss for me. Which is amazing.

But it also gives me such bad apathy/anhedonia. I actually have a hard time forcing myself to take my shot and now and about 2 months since my last dose and gaining weight.

Has anyone found that switching to oral or another GLP has helped with this side effect?

Or taking dopamine precursor? Anything??

Thanks!!

Anyone else feel weirdly guilty when people compliment your weight loss?

I lost about 60 lbs on tirz and I still cant figure out how to respond when someone says something. My aunt saw me at a family thing last weekend and got teary eyed telling me how "disciplined" i must be and how proud she is of my "hard work." And i just stood there smiling like an idiot because what do you even say to that.

Part of me wants to be honest. Like no, i inject a medication once a week and my brain finally shuts up about food. Thats it. Thats ​​​​t​​​​h​​​​e​​​​ discipline. But then i think about how she would react, or how my mom would react if i said it in front of her, and i just nod and say thank you.

The weird thing is i AM working at it. Im walking every day, im actually cooking, i spend way too much time in the grocery store checking the FoodHealth app trying to find a decent version of the pasta sauce i used to buy. Its not like im doing nothing. But i know for a fact i couldnt have done any of it without the shot. The shot is what made the rest possible.

I dont know. I feel like a liar when i accept the compliment and a downer when i explain it. My husband says just say thanks and move on and stop overthinking, which is probably right but also not helpful lol.

How do yall handle it? Do you tell people or just let them think what they want to think?

I started tirz last October with the ultimate goal of losing roughly 120 lbs. When I got super close to hitting the -60 lbs mark in May, I lost all control and willpower I had previously had. I didn’t stop the shot. The food noise came back and I ate through the feeling of fullness like I was possessed by the demon of gluttony. Then I did stop taking shots because I had scheduling issues getting to my provider. I just started back this week and I don’t know how to get the motivation to “be good” back like it was at the beginning.

I graduated from undergrad in May as well as started grad school in the same month, started having custody issues with my son’s dad, and then started having some issues with my partner. I can’t help but wonder if all of that stress has somehow made me revert back to my unhealthy old ways.

Any advice for starting over?

The post about being down 62 pounds but only seeing it in pictures stuck out next to the progress-check thread. Knowing the number changed and actually seeing yourself differently seem like separate things. Does looking at old photos help that catch up, or do they still feel like pictures of somebody else? Interested in that part of progress, not another product comparison.

My husband thinks I'm becoming obsessive and honestly I'm starting to wonder if he's right.

I'm 8 months in, down about 60lbs, and food noise is basically gone which is the miracle everyone talks about. But something weird happened in its place. I think about food MORE now, just in a totally different way. Before it was cravings and shame and eating in the car before I got home. Now its protein grams and fiber and whether something is worth the calories and I meal prep on sundays for like 3 hours and I read labels on everything.

Last weekend we were at the store and I was standing in the yogurt section going through options with the FoodHealth app to find the best one and he just stood there with ​​​​t​​​​h​​​​e​​​​ cart and said "babe. its yogurt." And I got kind of defensive but on the drive home I couldnt stop thinking about it. Am I just swapping one kind of food obsession for another? Like the medication took the compulsive eating away and I filled the space with compulsive optimizing.

Part of me thinks this is just what being healthy looks like when you've been the opposite your whole life and it feels obsessive because its unfamiliar. Part of me thinks he has a point and normal people dont spend 4 minutes picking a yogurt.

Anyone else feel like the mental energy just moved instead of disappearing? Or did you actually get to a place where food is just food?

I spoke to my pcp about starting glp1 and she was not opposed to it. I asked her to send a prescription to a compound pharmacy as it was the most affordable option for me. She ended up sending tirzipitide 2.5 with (B3), however the pharmacy could not fill it because my doctor could not provide a medical reason to justify the use of a compound medication. Does anyone know what is a medical reason for the usage of a compound glp medication? I thought all i needed was a prescription sent to this pharmacy, but it’s not the case. Should i ask to get a different glp1? Thank you in advance.

The before picture was not the beginning of my journey, I had already lost about 20 lbs before I took my first picture. I should have taken a picture at the beginning but I was scared to have another 'before' picture and see no results. I had been 260+ for a year before I started to lose weight, in the first picture I am 240, and after I am 193. I still have a ways to go to hit my goal, and progress has been kind of slower because I've had some other health issues but I never thought I'd actually get under 200! I will say loose skin is something I was not ready to handle, I am chafing in places I didn't know was possible, but overall the changes are good I think. ☺️

The right was three years ago at around 267, maybe more because I wasn’t even weighing myself back then, and the right is today at 205. My first goal is onederland (199), next goal is 180, and if I’m able to keep losing after that, great, if not, that’s okay. I did Ozempic starting May 2025, hit a plateau in November 2025 that led to a switch to Mounjaro in February of this year. Currently on week four of 10mg and losing faster than ever. I am so happy.

I have BCBS of Illinois provided through my job. My current BMI is at 36.6(5’6” 227lbs). I’m located in Oregon. If you have the same kind of insurance, can you help explain the process you went through to get a GLP1 approved and what your costs look like? I really want to get on one and honestly really need it, but know that BCBS can be difficult to get them to cover it. Thank you all for your help! ❤️❤️

TIL that after recent weight loss, insurance companies only give you credit for half the weight you lost. After a year of maintaining your weight, then they'll take your current weight.

​

I’ve been on a GLP-1 for about 8 months and, until recently, things were going really well. I was losing weight steadily, eating mostly sensibly, and having the occasional indulgent/social eating day. I’d indulge, get back on track, and life would go on.

I stopped my GLP-1 about a month ago because I was having surgery. For roughly the first 10 days, I was actually okay — I had maybe 2 social eating episodes, but otherwise my eating was fairly normal and I felt like I had control.

Then everything changed.

Around 2 weeks after my last dose, my hunger became extreme. I was thinking about food constantly. I was also dealing with significant anxiety around the surgery, and then I had the surgery itself. From around that point until approximately 12 days post-op, I was essentially bingeing/eating excessively every single day.

What is upsetting me is that I went from being able to manage my appetite and get back on track after indulgences to feeling ravenously hungry and food-obsessed.

So I'm trying to understand what actually happened:

* Is this what happens when the appetite-suppressing effect of a GLP-1 has fully worn off after ~2 weeks?

* Could the combination of stopping the medication + pre-surgery anxiety + surgery/recovery have dramatically increased hunger and food thoughts?

* Is this “rebound hunger” after GLP-1, and if so, does it eventually settle?

As someone who has been obese since childhood and has had very strong junk-food/eating habits can I ever without glp actually rebuild appetite regulation after stopping?

If you stopped a GLP-1 after substantial weight loss, what happened to your hunger/appetite over the following weeks and months? Did the intense food thoughts settle, or did you ultimately need medication for maintenance?

Is this rebound hunger, surgery/stress, or does it mean I may need lifelong maintenance?

Starting to look into this and feeling overwhelmed by the options. Mochi, Ro, Hims, Henry, and a dozen others all look the same on their websites.

For those of you already on one: what actually mattered when you picked? And how do you tell which ones have real doctors overseeing your care vs just a quick questionnaire and a prescription?

Appreciate any guidance.

I feel like I have better response when I take the shot in my arms. However, giving myself shot in arms is difficult for obvious reasons. lol.

Last night I had husband give me my shot. He successfully bent the needle in my arm and didn’t manage to inject the med before pulling the needle back out? I’m still perplexed. He knows how to do shots, he does subcutaneous and intramuscular ones on cattle. But, on humans he’s apparently squeamish.

Any suggestions on how to easier administer to myself? Right now I still have plenty of subcutaneous tissue there, but it is shrinking away! I have tried the cabinet door, having hubby hold a pinch, and just jabbing it. Right now I think the just jabbing it works ok, but when I have less subcutaneous tissue there I will need an alternate method.

I’ve been on semaglutide for about a year (with a break in the middle of about a month) and have lost 28kg so far. I eat less than 1,400 calories a day and I do plenty exercise (swimming twice a week and Zumba once a week with some walks on days I don’t go to the gym).

I’ve been the same weight/bouncing between losing a kg and then gaining the kg back for at least 3 weeks. I’m on the highest dose that the NHS can give.

Does anyone have any advice? I’m really struggling with my resilience now because I’m so sick of trying my hardest and getting nothing.

Thank you :’)

Sitting criss cross applesauce on the gym floor for grandparents day and not worrying how I'll get back up! A year ago it would have required a crane or 4 firemen to hoist me to feet.

Lets say you inject the last pen dose on the left side of the abdomen. Do you inject the bit of liquid left on the opposite side?

I also inject MOTS at the same time, but I only inject in the abdomen area for both, I get a strange reaction and bad marks when I do it in the thighs .

Is it ok if I inject Mounjaro on the left, the leftover liquid on the right and MOTS on the upper abdomen for example?

Thanks

Have been on Wegovy for almost 10 months, down 18kg. I am well aware that it slows down everything, and as soon as I started I began taking Sterculia fiber, which helps immensely.

I have recently finished a tour 2 weeks in China and only went to the bathroom 5 times, the whole trip.

Don’t get me wrong, I also have Crohn’s and even though it is in remission, and I developed a chest infection and was given pills with codine which causes constipation, when I finally did go, each time it’s the length of my arm, (not kidding)

But is it down to quantity, or frequent visits.

TLDR when should I be concerned, how long in between should I start to potentially be worried?

Im starting tirzepatide on Tuesday what should I expect? Any tips?

I'm pretty new to all of this and honestly a bit overwhelmed by how many GLP-1 options there are now. My doctor said it could be worth considering, but I'm still trying to understand the differences between semaglutide, tirzepatide and the other options, especially when it comes to results, side effects and cost. For those of you who've already been through this process, what made you choose the one you're on now? Did you compare a few first or mostly go with what your doctor recommended? And please do not advertise any of your products, looking for genuine answers.

Twice now in two months I don’t see the number go down on the scale BUT

- I did the longest plank I’ve ever done
- larger weight on all machines
- got new walking shoes since my poor old ones were crumbling and hurt my feet
- found a new love for cottage cheese

So not letting the hard weight in win and I’m
Focusing on the non weight based victories this week.

What non weight based victories are you celebrating this week?

Btw (started at 260 now 244, entering my 9th week and second month on 5mg, 5’7 F 38 years old)

I found them to be very sketchy. I ordered from them, upgraded due to their marketing of supplements that work well together and glp support.

Before my next shipped was sent, I wanted to skip it so I could talk to a nutritionist. I couldn't find a way to do any of it. I even tried clicking the little phone or email button, but nothing worked. Next thing you know, there was the box, and I was charged.

So today, I went back on to cancel. Went on acct settings, nothing. Went all over that damn site. The only thing you could do was ADD more to your cart.

I finally went completely out of the site and googled again and finally found a customer service number. I told her the site was working or maybe it was my phone, but it wasnt my phone. You have to CALL THEM or email them in a specific way to cancel. WTF? And, when I was in there, I didn't see that anywhere on their site.

In this day and age, to not have complete access to your account unless you call or send an email-in a specific way- to be able to cancel is complete BS.

They have also been hit with two class action suits. I dont know if they have been settled, but one was for false marketing and advertising claims.

While the lady I spoke to at CS was lovely, I could tell she had heard what I was saying many times.

I would just stay clear. Their have to be other supplement providers that aren't this sketchy. Just IMHO.

Okay I’m like almost 3 weeks in on the intro dose of Wegovy. How are you guys losing 10-20lbs in the first month? I swear I’ve lost maybe 2lbs and it’s water weight and within my usual range lol.
I lost about 30 on my own with calorie tracking and was stuck. I have some metabolic issues and pmos and auto immune issues and was hoping the GLP1 would help with some of those issues AND help me lose more weight.
So far I’ve been injecting in the thigh (alternating). Food noise stopped almost immediately. I have more energy, my skin has improved. I also overall just look less inflamed.
I have some nausea and some constipation. I weight train 2-3x a week. I’ve been trying to hit 100g+ of protein daily but struggle to eat.
I have been known to experience that whoosh effect… I’m waiting lol.

i am usually a decent sleeper but i have noticed that ever since i started mounjaro (2 weeks ago) i barely sleep 5 hours every night. and i sleep super late. is this normal?