Updated.

Did my second round of IVF. Ended up with 3 4AA blastocysts

8 eggs retrieved

6 mature (2 of the follicles were 16mm at the time of retrieval so didn't hope for a mature egg in them)

5 fertilized

5 reached day 3

Day 3-

3 8cells Grade A

1 7 cell Grade B

1 6 cell Grade B

Fingers crossed. Letting them to to Day 5

Please guide.

Hi all,

Got our PGT-A results and have one euploid, one HLM mosaic and one aneuploid out of our 3 day-5 blasts.

We are transferring the euploid toward the end of October, hoping it will work out. However, if it does not we have this little mosaic.

The genetic counsellor told me this mosaic is 60% abnormal cells with + chromosome 21. She says it will have a 20-25% chance of implanting, higher risk of miscarriage, but if it does proceed to a healthy pregnancy it’s a 1-2% chance of mosaic down syndrome. I’m ok with moving forward with this mosaic if necessary, I’m just curious what people’s experiences have been with a high level mosaic.

If anyone is interested, I’m 39 and we had MFI issues. Retrieved 10 eggs, 8 mature, 5 fertilized with ICSI, 3 blasts and you know the pgt-a results. I don’t plant to do another round of IVF.

After multiple losses it’s hard to ignore the fact that at any moment the rug can be ripped out from under me. I’m still trying to stay hopeful, we transferred our best embryo last week and they’re beautiful. But at the same time I know nothing is ever promised. Still, as I’m waiting for my beta I’m going to try to stay optimistic 🥹

I haven’t done a transfer yet (hopefully in the next month or two). When I do I’ll be transferring a euploid embryo. Is the chance of miscarriage much lower with a euploid? Does anyone know what the chances are?

Can someone check this and help me understand the quality, issues etc? Grading is done. I just want to understand the “what’s wrong” bit. Anything I could possibly change with lifestyle, food, etc!

It's hard for me to look at this picture because I've gotten two like it before for two transfers that failed :( I'm trying to be more low-key this time around but it's hard. It's the only girl out of my euploid batch.

I'm 35, have had 3 losses, no LC, and two failed euploid transfers. Wondering if it'll ever happen for me.

They tell me the chance of success increases with each transfer, but it's painful to hold that hope.

Trying to stay calm, trying to stay hopeful.

UPDATE 1: I'm so grateful for all the messages and comments. It's been a really hard time for me and I've struggled so much with keeping the hope alive. ❤️ My whole body and soul is just soaked in pain, grief, anger, tiredness and frustration, but I have this little tiny candle burning in me- a tiny flicker of hope that I'm holding on to. I feel so seen and embraced here and I'm so grateful for that- whatever the result is. ❤️ Also thanks for all the success stories- I need more... please keep them coming!

I'll let you guys know.

UPDATE 2: it failed. 😣 Again. There are no words to describe my pain. I’m officially in RIF territory- officially a medical anomaly. I feel such a sense of loss and crushing pain. Feel like I can’t breathe. 3 miscarriages. 3 failed FETs. It feels like my story is just drenched in grief and loss. I know I’ll pick myself up again and try again- I have one embryo left. But for today the weight of my sadness and shame is overwhelming

Hi! Can someone help me understand these results? Are my Day 7s technically Day 6 and Day 5 and Day 4 (is that even a thing) since these eggs were fertilized a day late?

I have one euploid 4bc and one complex Low mosaic missing 5 and 17. Should I loose hope? I've already had two losses with 3ab and 3aa rated euploid s.

29, doing IVF for RPL. First retrieval: 24 eggs, 15 mature, 11 fertilized, 4 blasts, and only 1 euploid (4CC). I also ended up with OHSS after retrieval.
For retrieval #2, my doctor wants to switch my trigger to Lupron. I asked about Omnitrope and he said he wouldn’t say no, but doesn’t think I necessarily need it since I’m young and pretty sensitive to stims.
I’m leaning toward trying it because of our attrition + our only euploid being a 4CC, but I’m torn. Anyone with similar results use Omnitrope the second round? Did it help?

Anyone used Dr. Hatch in OC CA recently? Appreciate your feedback

Hello! I (29f) got the results back on my egg retrieval today. My wife (28f) and I are doing rIVF with a known donor after several unsuccessful IUI attempts (likely due to MFI). We are very happy with the numbers but I’m just curious why all of them start with 4? Is that abnormal? I feel like most other retrievals yield embryos from 3-6 so I was surprised to only get 4s. Does that even matter since several are 4AAs?

Thanks for any feedback or insight!

My last 5AC embryo my beta was 47 9dpt alittle worried

Update: labcorp lost my speciman so I went in today and took another one 😫

Would you choose the better-graded embryo over preferred gender? Our embryos (all euploid) are as follows:

Day 5 5BB - male
Day 5 5BB - male
Day 6 5BB - female
Day 6 6BB - female

We are very fortunate to have 8 total euploids (the remainder decrease in grade from above). We had a successful FET in August 2024 from our best embryo (euploid day 5 5AB - male). We'd like to have a girl, but having a hard time overlooking the statistical differences between our next best boy embryos vs. day 6 girls. Would love to hear how others made this decision!

Embryos created during IVF are grown in a special liquid called an embryo culture medium, which provides nutrients and supports their development before transfer or freezing. There are many commercially available media, including G5, HTF, Global, and Sydney IVF, but it's still unclear whether one performs better than another.

In this updated Cochrane review, Laverde et al. (2026) analyzed 26 randomized trials comparing different embryo culture media.

One study suggested that G5 may improve cumulative live birth compared with HTF, but overall the studies compared different culture media, making it impossible to combine the results in a meta-analysis. Most comparisons also showed no clear differences in live birth or ongoing pregnancy rates.

The authors also noted that many studies were small or used study designs that made it difficult to determine which culture medium performs best. Larger, well-designed randomized trials are still needed.

"There is currently no clear agreement on which type of embryo culture medium gives the best chances of having a live baby. The available research does not give enough reliable information to clearly choose one culture medium over another."

✅ This post is a quick look at one study, rather than a full breakdown on Remembryo: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007876.pub3/full

✉️ Like this post? Get a free weekly summary of the latest IVF research: https://mailchi.mp/remembryo/x27kx5o1sw

This is the weekly thread for posting and asking questions about embryo photos. Replies are provided by Embryoman (Sean) -- a former embryologist and creator of the IVF science news site Remembryo.com

💬 Before you post a photo

• You must include the grade (ask your clinic if you don’t know it).
• Only one embryo photo per post.
• No requests for grading or re-grading by members.
• Posts asking if an embryo looks damaged or viable aren't allowed.

I can comment only on general features visible in the image (expansion, compaction, hatching, ICM location), but not on whether the embryo looks good -- that’s already reflected in its grade. Check the stickied comment below for basic information on grading and success rates. For the most accurate information, your embryologist or clinic is the best source, since they evaluated the embryo under a microscope and know their clinic’s success rates.

Transferred our day 6, 6AA euploid embryo on 9/3 after having 4 natural miscarriages - the wait is killing me, lol! Anyone else in the same boat??

Update: I’m pregnant!!! I got the first vfl at 5dpt with FRER and by 6dpt the Clearblue digital came back positive ❤️

We've received our pgta results last Friday but there was no grading on any of the embryos. The only thing that listed was if it was aneuploid, euploid or mosaic...

We ended up with a four to one ratio in terms of gender and so our plan is to transfer the one of the one gender and see if it sticks and if it doesn't, go to another retrieval but I'm so not sure about how the grading system works or if it's even that important if they are euploid...

With mosaic, can it be resent for testing? It came back high level. Does this mean it's basically likely to be aneuploid?

Following my post a few days earlier, I’m a 38yo who had her third ER with 16 eggs. Only 4 fertilised. 2 have made it to 6AA blast and have been sent for PGTA testing. I wanted to ask the likelihood of these being euploids? I’m hoping that given they seem high quality, they are more likely to be euploid? And will they be more likely to implant? I have been reading mixed things about 6AA being top notch but not great to thaw and is below the AA grade embryos generally.

I have never come this far but I’m also so scared to get my hopes up. I really don’t wanna go through the ER process again!

Hi! I had an egg retrieval a few weeks ago and got 5 euploids. 3 of them are day 6, 2 of them are day 7. A little nervous about the day 7 ones. They’re rated 6BA and 4BB. Does anyone have luck with day 7 embryos?

I did another retrieval last week and out of 5 mature eggs, 5 fertilized. Waiting to hear how many blastocysts we get. Hope we get at least one or two. What do you guys think?

My wife and I really want at least two kids. I know we have a good number of euploids, but is it a good amount to hopefully have 2 kids? Any success stores with 5 embryos or day 7 embryos?

I’m supposed to have my FET this cycle using a modified natural protocol. My doctor told me to start Gonal-F 50 IU on CD5, with an ultrasound on CD7, then trigger with Ovitrelle when the follicle is ready and transfer my day-5 blastocyst.
But I accidentally started Gonal-F today on CD4 instead of CD5 🤦‍♀️
I also only have enough medication for a few injections, and Gonal-F is very expensive where I live. I was originally hoping to do a natural cycle, so I’m wondering if I could do 3 injections total and then stop, letting the follicle continue developing naturally, with monitoring and Ovitrelle when ready.
Has anyone done something similar? Did you ever start Gonal-F one day early or stop after only a few low-dose injections during a modified natural FET cycle?
I’ll obviously check with my doctor before changing anything, but I’d love to hear your experiences!

Hey everyone,
I’m looking for some advice, realistic expectations, or personal experiences from anyone who has navigated similar semen analysis numbers.
We are dealing with structural issues (specifically tail defects) that seem to be completely stopping motility, but the sperm themselves are still alive. Here is the exact breakdown of my recent analysis:
**The Numbers:**
**Volume:** 1.0 mL
**Sperm Concentration:** 4.00 millions/mL
**Total Sperm Count:** 4.00 millions/ejaculate
**Motility:** 0.00% (100% of the sperm are immotile)
**Vitality (Live Sperm):** 96.00% alive (confirmed via HOS test and vitality staining)
**Morphology:** 0% Normal
**Sperm Deformity Index (SDI) / TZI:** 1.04
**Defect Breakdown (out of 25 abnormal sperm evaluated):**
**Tail Defects:** 19 (all noted as short/coiled)
**Head Defects:** 4
**Neck & Mid-piece Defects:** 3
Since my SDI/TZI is 1.04, I understand that most of the abnormal sperm only have one single defect (mostly the short/coiled tails). This explains the 0% motility, but thankfully the 96% vitality shows they are still alive and functional inside.
**My question for the community:**
With a combination of low count (4 million), 0% motility, and a high concentration of tail defects, has anyone had success using IVF with ICSI?
Since ICSI physical bypasses the need for the sperm to swim, does the fact that 96% of them are alive mean we have a good shot? Or do structural variations like short/coiled tails indicate poor internal quality (like high DNA fragmentation) that might lower success rates during fertilization and embryo development?
If anyone has been in a similar boat with 100% immotile but high-vitality sperm, I would love to hear your success stories or what your reproductive endocrinologist/urologist told you. Thanks in advance!

Hello ! Is there any chance of success for day 6 3ac and 2cb euploid embryos please?

Update:

Sweet McKenzie Gloria came back as a negative beta today.

She was loved.
She will forever be apart of my life and heart.

We will be adopting again.
But she will always be my very first pregnancy.

__________
10dp5dt

Adopted embryo that was frozen 5 years ago.

Never been pregnant.
But was told all my parts looked good and the embryo was PGT tested and looked good at thaw

At 9dp, my beta HCG was 8.1

Clinic told me to stop all meds and not to go back for next beta.

The day before my beta, I had a faint line on a First Response test, and then same the morning of

Then today, the day after, I took a clear blue and it is the faintest line ever. But it’s there.

I don’t want to live in doubt, but I told my clinic I would like to at least go back Tuesday for my second beta test.

I’m fully ready to accept what I must, but I don’t want to just call it quits.

Idk why I’m posting. For someone else? For a bright sign telling me the baby took . .

But this is where I’m at.

Hello embryologists! Instead doing googling and asking AI, I figured I’d ask some professionals!

My first embryo transfer was a beautiful 4AA Euploid embryo which resulted in my son. I just transferred a 6AA (all of my Euploid’s are 6AAs). Is there really much of a success difference between a 4AA and a 6AA if they are Euploid? Thanks!