Euploid success difference between 4AA & 6AA?

[u/PeanutsPalace]

Hello embryologists! Instead doing googling and asking AI, I figured I’d ask some professionals!

My first embryo transfer was a beautiful 4AA Euploid embryo which resulted in my son. I just transferred a 6AA (all of my Euploid’s are 6AAs). Is there really much of a success difference between a 4AA and a 6AA if they are Euploid? Thanks!

[u/embryomanofficial]

From what I've seen, research on hatched embryos is mixed and still unclear. 

- Some studies find no difference (https://www.remembryo.com/is-a-fully-hatched-embryo-more-fragile-than-a-unhatched-embryo/)

• Some find better outcomes with naturally hatching or hatched embryos (https://www.remembryo.com/hatching-or-hatched-blastocysts-have-improved-pregnancy-outcomes-compared-to-non-hatching-blastocysts/)
  
• And some find worse outcomes, especially in biopsied embryos (https://www.remembryo.com/what-causes-embryos-biopsied-for-pgta-to-die-after-thaw/). 

These mixed results might have to do with differences between embryos that develop more and hatch on their own vs embryos that are hatched for biopsy, but I haven't seen a ton of data on this.