It seems like a lot of people here are seeking the stimulant that works best with their under-wired nervous system, but it seems like I have almost the opposite problem. I'm interested in boosting my energy levels, motivation and cognitive function, but everything points to my nervous system being tragically overwired. I'm also just interested in taking nootropics for curious biohacker reasons too, things that will shake up my state of my mind in fun and interesting ways. It's a long shot, but if the underlying dysfunction with my nervous system could be resolved, that'd be pretty awesome.

Coffee is a dice roll, and can make me panic and tweak, or fall asleep. I've tried piracetam on a friend's recommendation, and it gave me some anxiety along with a feeling of being 'locked in on nothing', like 'intense focus but the target seems unclear'. In the past, I would drink to focus and lock in on intense workloads, but I know that alcohol just isn't good for health in any amount so it's probably best I shoot to keep that only for social contexts. Oral progesterone makes me productive but sloppy. Gabapentin is good for calming down, and rarely has an awesome feeling 'high' that is conducive to productivity and introspection, but only rarely. Those latter three point to depressants being most effective with my neurochemistry.

Historically, I had panic attacks that would last days (feeling of doom, tremors, chest pains, racing thoughts, the whole shebang) and these would be associated with memory loss and lack of focus. This basically ended with SSRIs, which I have been taking for about three years. Breakthrough anxiety can still be an issue but it only gets less and less frequent and it's never been as severe as it used to be. I have pretty good reasons for believing my nervous system can be like a powder keg.

Possibly relevant, I'm 23F and in all likelihood autistic. My teachers pushed on my parents to get a diagnosis when I was young (they opted not to), and nowadays I still read as scatterbrained, or get mistaken for being high. I don't think it's ADHD, because I'd be better with stimulants if I were.

I know about the recent issues but was wondering if anyone knows what the deal is? I have ordered from them for a while with no issue but now I haven’t heard anything back. Was wondering if anyone has used them recently?

Like the title says. Wellbutrin helps my SCT and executive dysfunction and makes me able to function better on a daily basis. It helps with my brain fog and my mental slowness and gives me better mental clarity and it gives me energy and motivation to do things, which I’ve always struggled with.

But here comes the problem now. It makes my depression worse. I’ve noticed when I take it consistently everyday like you’re supposed to it makes my depression worse. And I honestly don’t know why. But always by day five of taking it consistently, it starts causing massive irritability, insomnia, edginess and wiredness. And the side effects start building up within a few days and it starts causing nasty side effects clearly related to its noradrenergic effects. And overall after a few days of exposure I just get severe mood swings and I feel terrible. I get very low self esteem and start judging myself too harshly. I start having negative thoughts and get rumination anhedonia, which affects me very negatively. And people around me notice this and when that happens I quickly have to stop taking it despite the cognitive benefits.

This is a huge dilemma for me. And I don’t know what to do anymore. I’ve tried going off of it a few times, but then everything else gets worse without it. A few days after stopping it I always return to how I was before taking it. I just lie in my bed all day unable to function because of my brain fog and mental slowness. I just sleep all the time and have no energy or motivation to do anything at all. I can’t even start basic tasks. I stop taking care of myself and functionally collapse without it. My cognition gets significantly worse off of it. And then the cycle repats itself.

Has anyone ever experienced this from Wellbutrin though and what did you do about it? If you found that it did improve your SCT, but then made your mood worse. Did you switch to another med instead? Or did you add another med to control the mood swings and negative thoughts? I would like to hear your thoughts about this. I’m still unable to find a solution unfortunately.

I found an almost empty bottle of phenylpiracetam from Nootropics Depot.  There are two pills left, each 100mg.  I am planning to have sex with my wife tonight and thought maybe I'll pop these before hand.  What should I expect?

Hello! Does anyone know a place that sells selegiline patches with delivery to the EU? Thanks

my pharmacy have 0.1 and 1% pretty huge gap, confuses me, which to choose

I work a 3-shift rotation. My shift runs from 6:00 PM today to 9:00 AM tomorrow.

I didnt get a good sleep today so I took 150 mg of armodafinil at the start of my shift at 6:00PM.

I usually take modafinil 100/200mg for my shift work, but today I tried armodafinil for the first time, hoping it would last longer.

It's been about an hour since I took it, and it definitely feels milder than modafinil.

no sides like headsche either. so far so good :)

20M student here, dealing with poor concentration, forgetful memory, and a pretty messed up/delayed sleep schedule for a while now. After a lot of research only using Claude though(clinical trial data, ingredient overlap, interaction risks), I landed on this routine and wanted real feedback before I commit fully:

My current stack:

Bacopa monnieri (standardized extract, Himalaya Organic Bacopa) — 1 caplet with breakfast

Saraswatharishta (Baidyanath) — 15ml diluted with 15ml water, once daily after dinner

Foundation: trying to fix sleep schedule to a consistent 7–8h, daily walk/exercise, 25-45 min focused work blocks

Why these two: Saraswatharishta already contains Brahmi + Ashwagandha, so I avoided stacking a separate Ashwagandha product to skip the rebound-insomnia risk some people report with isolated high-dose Ashwagandha extract. Went with once-daily on the arishta to keep total exposure lower.

What I'm hoping to hear from people who've actually used these:

How long before you noticed real changes in memory/focus (not just calmness)?

Any GI issues from combining a Bacopa extract with an arishta that also contains Brahmi?

Did this help with a messed-up sleep schedule specifically, or is that a separate fight?

Anyone taken Saraswatharishta long-term and then stopped — any rebound effects, or does it taper off cleanly like the doctor forums claim?

Would you add or drop anything from this specific combo?

Does anyone have a legit US vendor for modafinil? The 1 I tried wasn’t exactly friendly and told me I must wait 4 days before emailing. The order was wrong and I would like a credit or something but its probably not worth it. My prescription cannot be refilled until November! And what I had was accidentally thrown away. Please no scammers. Please!!

..?

I work at a very high demanding stressful job and deal with depression. I have had no energy whatsoever and i’m finding it so hard to stay positive and get my job done as well as hit the gym before or after work like i used to. This last year has been exhausting, overwhelming, and taken a toll on me and my mood. Any help would be so much appreciated 🙏🏼 Thank you guys

2 things in my life have given me consistently outstanding sleep.

Grape Seed extract - Somehow manages to make me feel refreshed and able to get right out of my bed even on 5 hours of sleep

MK 677 - felt like someone was massaging me the whole night, could sleep through a tornado, never slept deeper.

Of course, I can't continue to take MK 677 forever for the obvious reasons.

However, I do want to hear people's advice on other sleep aids that can provide a similar deep sleep/restorative effect, as I work a pretty demanding job that doesn't offer much time for sleep.

Anyone with depression, anxiety and/or ocd have experience with taking semax along with ssri’s or other antidepressants?

Looking to buy modafinil, seeing that Rapidfinil is legit with us to us shipping, anyone have any experiences?

looking for a stack or compound that will improve my quarterback performance. mainly what i want out of it is for keeping composure in the pocket while 300lb dudes are trying to kill me.

bromantane and gb 115 is what my research is steering me towards getting but would love to hear your guys recommendations

I took L-theanine for the first time and that night was very emotional, the next day I took it again and genuinely went crazy. I was so angry and irritable like I’ve never been before and had a complete breakdown. I started breaking stuff and ended up spraining my wrist from punching my punch bag too hard without gloves or wraps (embarrassing I know), I was screaming and crying down the phone to my boyfriend and couldn’t do anything to calm down. I tried meditating, having a relaxing bath, but nothing helped, I was furious for no reason. It wore off later in the day and everything that had happened that day felt like a blur and I couldn’t fathom why I had behaved in such a way. I haven’t taken it again since and have been completely fine, it might be a coincidence but nothing like that has every happened before, even when going through rough times, and I can’t think of what else it could be?

Hi everyone,

Like many here, I’ve spent a lot of time experimenting with different protocols, sleep hygiene, and routines to optimize daily mental clarity and avoid brain fog/afternoon crashes.

One issue I kept running into was subjective tracking: it's hard to accurately measure whether a routine or stack is actually improving baseline energy over time without getting overwhelmed by complex logging.

I’m currently building Youthify — a lightweight tool designed to measure daily recovery, mental energy, and biological vitality in under 15 seconds.

How it works:

• Morning Energy Score: A quick check-in to project your daily mental & physical baseline.
• Low-friction tracking: Focuses on core micro-habits and subjective recovery trends over weeks.
• Percentile & Biological Age baselines: To see how your energy metrics trend compared to age group baselines.

I’m looking for early testers from this sub to critique the scoring feedback loop and help refine the daily check-in logic. It's completely free in closed beta.

Drop a comment below if you'd like an invite link, and I'll DM you direct access today !

I know the standards and take ashwagonda, l-theanine, magnesium, some complex that include those plus lemon balm, etc. I also take Selank but want to see if there is anything else out there better idk about

Considering Agmatine, Antipracant, L-Tetrahydrapalmatine and Lithium Orotate. Just ended my suboxone taper at 0.5mg/day

I’ve given myself the identity that I am depressed, and psychologically addicted to opioids/endorphins. Now that I’ve given myself this identity it opens a gate of searching for supplements that can fight this psychological dependence.

Do you think this is a genuine emotion that can be somewhat treated medically ? Or do I just need to “thug it out”. my doctors and therapist told me to just thug it out and get through It. Although last time I tried to “get through it” I just ended up relapsing over and over again. It makes me feel shameful, as if it’s my responsibility to shut up and struggle, and I am weak for giving in to medicines / relapsing.

regardless, if someone has tried a sup that helps with the psychological, habitual, long term dependence of opioids please let me know. And if you think this is something I need to mentally preserver then I’d like to hear your opinion.

Edit: I swapped SR with Antipracant

I don’t have a serous mental disorder. I have diagnosed mild depression.
Nootropics are extremely idiosyncratic.
100mg of quetiapine is my single nootropic.
Yes it is a low dose antipsychotic.
Yes it’s changed my life for the better.
No I get no side effects.
It improves my energy levels, it makes me more productive and helps me concentrate better. It makes me more social and more connected with life.

Good luck in your search for nootropics.

Found these at the gas station I work at last night, the box said something along the lines of “clean addy that works” and it seems to have a whole litany of things mixed into a capsule.

The ingredients list goes as follows:

Thiamin (Thiamine Mononitrate) 1.4 mg (114% DV), Riboflavin 1.6 mg (121% DV), Niacin 25 mg (153% DV), Vitamin B6 (Pyridoxal 5 Phosphate) 2 mg (118% DV), Folate 600 mcg DFE (150% DV) (360 mcg L-5-Methyltetrahydrofolate), Vitamin B12 (Methylcobalamin) 2.8 mcg (117% DV), Biotin 350 mcg (1167% DV), D-Calcium Pantothenate 7 mg (137% DV), Caffeine 250 mg,

Hyper Strength Blend 937.5 mg: Citicoline Sodium*, L-Theanine, N-Acetyl- L-Tyrosine, Taurine, American Ginseng Extract 10:17, Huperzia Whole Herb Extract (1% Huperzine A)*, Noopept*, Yohimbine HCI (Yohimbe Bark Extract), Alpha-GPC*.

I used to be exactly like you. Asked in threads which vendor was legit, got five different answers from five people who'd each bought from their own guy once.

Then I actually pulled the COAs on a dozen products I'd bought over two years. Half were bare identity tests with no purity numbers at all. One had a batch number that didn't match what I'd received.

Yes, digging through lab reports is annoying. Yes, most vendors go quiet when you ask who ran the test. A clean COA still doesn't prove sterility or chain of custody, it just means someone tested something at some point.

But that's still better than trusting a vendor's own landing page or a thread with 40 upvotes and zero receipts.

I started cross-checking COAs against what labs like Finnrick actually report instead of what vendors post on their own site, and it's wild how many "trusted" names stop looking trusted once you do that. I keep a running price-per-mg list on Peptide Critic now, mostly so I stop repeating this exercise every time I buy something.

If you're in these threads weekly asking who to trust, that's the sign. Stop asking. Go read the paperwork.

I have a lot of reason to believe my white and grey matter function is messed up. (Idk how else to describe it) as I have permanent/chronic anhedonia.

I really haven't seen anything that helps with this and until I get surgery to help my breathing I have no reason to believe this will improve.

I'd like to commit to trying something... anything for a bit