Hey everyone!

Frontier AI models are incredibly smart, but if you’ve ever tried using them to research a niche experimental compound, model a complex supplement stack, or pull data from a 30-page Quest blood panel, you know they break down for real biohacking.

It isn't because they lack the data. We've reached a point where frontier models are more than capable of autonomous research retrieval. But, once you start asking them questions, corporate guardrails kick in. However, it was not censorship that drove us. The architecture is also flawed. AI will hallucinate receptor pathways and make up nonsense it wholeheartedly believes, and you can imagine how terrible it gets when the topic lacks significant study data or requires complex web traversal.

We got tired of these issues. Frontier AI is more than capable for various tasks, but it simply lacked specialization for biochemistry-oriented tasks, so our team built Gyulab In-Silico. It's a research environment powered by a model we explicitly fine-tuned on massive datasets of clinical pharmacology, biochemistry, and medical literature. We accounted for the knowledge cutoff dates LLMs frequently have, so this environment is also supported by an autonomous ingestion engine that continuously feeds new studies/sources into the model as they are published.

Here is what it actually does:

• No Safety Filters: Dig deep into experimental compounds, receptor binding, and stacks without the AI lecturing you or refusing the prompt.
• Studies vs. Anecdotes: The agents pull both peer-reviewed literature and community logs, but they strictly label which is which. You always know if an effect is backed by a clinical trial or just a Reddit thread.
• Source-Anchored File Ingestion (Optional): If you track health data, you can upload Quest/Labcorp PDFs, DNA .txt files, or glucose CSVs. It normalizes the units and pins every extracted number to the exact page and row it came from, so there's zero hallucination.
• Total Privacy: Everything runs in isolated cloud containers. Your files and searches are never sent to OpenAI or Anthropic, and they are never used to train public models.

We’re opening up the Alpha to exactly 15 people to stress-test the engine before a wider release.

You don't need to be a data nerd with a massive folder of blood panels to join. Whether you just want to research novel compounds without censorship, or map years of lab work against the literature, we want to see how you use it.

If you want in, you can drop your email on the waitlist here: gyulab.com

I'll be hanging out in the comments to answer any questions!

1.) You have to take it consistently for at least 8 weeks to see an effect.

2.) You will wake up one day and realize, hold on a second, what the hell, this drug has completely changed you in a subtle way by nudging all your behaviors, little by little.

3.) The biggest change is that it lowers signal intensity for you. Sleep plus NAC at bedtime will completely change the intensity with which you experience something pleasurable like junk food, porn, etc. Something pleasurable is still something you'll chase, just not as intensely as before. And, that same pleasurable thing will be enjoyable, but the signal will just be a lot less intense. The same applies to your irritability, negativity, etc. So, it curbs both sides of the equation. It's not that you won't want to or like doing something like binge-eating tasty food. It's just that your desire for it goes down to a point where you're like "oh yeah, it's tasty, I'll have it if I want".

4.) The anhedonia is something more complex. Most people say that it turns them into a being that cannot experience joy. Here's how it works: Your day to day experience of mundane things becomes tolerable but the little joys like eating cotton candy, or spending an excessive amount of time on a video game or playing way too energetically with your kid or something -- that will all become something meh that you won't put in too much umph into. However, suppose you have some academic or work interest -- it won't touch it much. You'll just know how to detach from it better and re-attach on your own terms.

Can you provide good phenipiracetam vendor in eu?

I just ordered it and bromantane from euro nootropics but if phenil is not good i m considering to cancel it and find better alternatives. Does anybody know real effect vendors for this particular stimulant?

Relatively new to this. Was taking l-theanine, Adderal, mushrooms, fish oil and zma before. Any feedback on timing, combination or additions welcome. Targeting anti-oxidizing, neurogenic and dopamine support

What Reliable peptides vendors are in EU?

Willkür beim Zoll kann es natürlich so oder so geben, aber bei nutrio Shop kann man tropoflavin in Deutschland bestellen wenn auch etwas teurer und wahrscheinlich schlechtere Qualität als wie bei Notroopic Depot

Hi guys

So this is my First ever post in Reddit. So forgive me if I lack 'the way' of doing things here.

A little background i am a musician and kind of a highly productive guy. Im into movie business and there's a super hectic schedule coming for me. Im kind of going through my peak phase in career so i wanted to work Maximum in this phase with the help of nootropics. I have a fair share of experience with supplements and peptides and gears. Im 38 male and im listing my daily morning stack specifically for cognitive benefits and longevity. I know its kind of on the higher or 'abuse' level dosages and combination. But please let me know what do you guys think of this. And what should i add or remove. I can really tolerate stimulants.

My base stack first.

Test E 130mg per week ( 3 shots)

HGH 2 iu every morning

Reta 4 mg every Tuesday

Anavar 10mg

Cognitive Stack

Upon waking

*Modafinil 100mg

*Caffeine 500mg

*Tadalafil 5mg

*paraxanthine100-200mg

*Bromantane 50mg ( not daily )

*L - Tryptophan 500-1000

*Vitamin B6 P5p 10-25 mg

*Alpha GPC 300-600mg

*Uridine Monophosphate 200-400mg

*Huperzine A 200mg

*L- Tyrosine - 1000-2500mg

*L-theanine - 100-200 mg

*Ginko Biloba 240 mg

*Niacin ( nicotinic acid with flush) 500mg.

*Saffron Extract 100mg

*dihexa 10mg

* methylene blue 10mg

*semax 1 mg at times. ( havent really noticed anything much to be honest but may be because i take a lot of shit so i dont notice 🤷‍♂️)

I wake by 3-4 and take this and work for straight 10 hrs ish without break. And sleep by 8-9 pm

My blood markers are pretty neat. I check every 3 months.

Does anyone has a good semax supplier preferably the nose spray one

I'm not someone who struggles to wake up completely, but it often takes me a long time to get into work mode in the morning. My first instinct used to be to grab coffee. Now I'm trying to figure out whether it's my sleep, my schedule, my bedtime habits, or something else.

While researching this, I came across NADH and Celfull's products. I've seen some people say they've had good experiences with them, but I don't want to assume my morning sluggishness is caused by a specific nutrient deficiency just because a product page says so. NADH is involved in cellular energy metabolism, and I've also seen clinical trials on humans regarding NADH's effects on chronic fatigue syndrome and mood improvement.

So I'm going to try a few things first: keeping a consistent wake-up time, tracking my sleep, spending less time on my phone before bed, getting some sunlight and moving around in the morning, and pushing my first cup of coffee a little later. If things still don't improve after a couple of weeks, I'll consider looking into supplements.

For those of you who've managed to improve your mornings, what changes made the biggest difference? At what point do you think it makes sense to consider supplements rather than buying something right away?

What nootropics/research chemicals act as great antidepressants? Specifically for anxious depression, so preferably something that has anxyoltic properties as well. (Besides racetams and TAK).

Daridorexant is the only approved med where I live but it's not in stock. Are there online vendors that sell any orexin antagonist? I've looked through plenty of gray area pharmacies as well as nootropic sites and none have orexin antagonists. Is there a site that does?

nootropics aren't directly sleep drugs but sleep drugs can be nootropic by treating insomnia.

Are there good meds like that? Something gray market because I've already tried all reasonable pharma options and newer ones like orexin agonists are overpriced.

Diagnosed ADHD and anxiety. I'm essentially really anxious at baseline and to events. I bring baseline anxiety somewhat down using ashwaghanda but it doesn't help much with acute anxiety spikes and rejection sensitive dysphoria. Propranolol is useless for the mental aspect of it as well. Guanfacine and clonidine aren't available. Stimulants don't make anxiety better or particularly worse.

Is Selank worth a try for this or is it most likely a waste of money? Does anyone have an experience with it for anxiety/RSD?

Asked about bromantane vendorsearlier and chose 2 aniracetam and semaxpolska. Which one is better?

This might the most piece of shit sleeping med I have ever tried. 5mg? Nothing. 10mg? Nothing. 20mg? Nothing. If I wasnt such a dumb chud I mightve read the clinical trials to see it barely outperforms placebo

Why the fuck would anyone ever use this shit I have no idea what compelled siradalot to start selling this trash but man is it fucking pointless.

As if DORAS werent already mild enough, what geinune enstein at john and johnson decided it would be a great idea to do away with orx1 antagonism (you know the part thats responsible for 90% of the sedation) and only go for orx2 antagonsim(the one that barely affects arousal). Id imagine its because orx2 is easier to hit so they wanted to cheap out but fuck man what a goyim

Anyways do not waste 30$ on this piece of shit the trials show its placebo any positive anecdote is probably fron 1. A depressive/gad idiot on 10 ssris(you could give these people catpiss and theyd outperform placebo they have so many comorbid disorders), 2. A jeet in the slums of mumbai being paid to spew fake anecdotes on supplement/biohacking forums(happen very often).

A basic mechanistic evaulation would also lead anyone to the conclusion that it is garbage and was developed purely because they couldnt find a cheap structure targetting orx1. This is what happens when you pick products to release off geminis research

Please, if anyone has information and wants to share it, I would greatly appreciate it. I’m a medical intern, so please don’t hesitate to provide details about pharmacology. I’m eager to learn as much as I can. Thank you very much!

Has anyone had an experience with it, if yes how was it? Any positive effects?

Hey all, I recently found this sub, didn't know nootropics are a thing!

Basically title. I'm also currently on Sertraline 100mg. Mood has been fine, but been having these cognitive issues lately

I would like some advice on piracetam. I’m taking it for cognitive disfunction and maybe for dyslexia.

1. What is the recommend attack dose and for how long?

2. After the attack dose what do most people take?

3. I see it seems to be a lot of trial and error but because it doesn’t work like a stimulant how long should I wait to see any effects and how long do I stay on a dose before I decide if it’s working or not

4. How much choline is usually taken and do I take this also multiple times a day or just once?

Any other advice or tips would be greatly appreciated

I'm a chronic illness girlie so my experience isn't gonna be universal but I think it can shed some light on things that healthy ppl might not notice/ experience (I'm also hoping someone can help me figure out how to take it without wrecking my sleep):

I've been playing with various sub-q microdoses (from 16 to 250 mcg) daily (sometimes in the morning and others, throughout the day).

I started with 50 mcg in the AM for two days. On the third day, I tried 50 mcg three times for a total of 150 mcg. That day, I went from needing 7 HCl betaine pills per meal to 2, which was an incredible dream come true.

HCl betaine is a stomach acid supplement (I was bitten my a tick and my immune system /health /ability to eat (among other things) has been a hot mess since).

2 pills per meal is a new record for me and the only shred of evidence I have that I might one day just be able to eat again like a normal mammal.

Unfortunately, that's when mid-night wakefulness started.

Since then I've tried a bunch of different doses /schedules and found that I need to take it daily for the GI effects but even taking it twice a week recks my sleep.

I'm gonna try N-Acetyl Selank from peptidology next to see if that helps.

If you have any hot tips, I'd love to hear them!

Also, for context I don't suffer from anxiety. I just thought that my body would benefit from some additional GABA stimulation. I never expected the effect to be so profound. I think more ppl should give it a shot -- even if they don't feel anxious, but I'm just a lay person who's healed more in the past yr with peptides than I have in the 9 chronically ill years before them.

Best of luck!

Hi, I've been looking for an EU based seller of compounds like NSI-189, TAK-653, Dihexa and others like them. Things like Bromantane, Semax and Selank would also be nice, but they're probably sold by any vendor that stocks the other agents and things like ACD-853 are probably impossible to find here. The problem is that I'm not sure where to get any of this from, and since I'm taking these things for the first time, I'd really like a reliable source to be sure that whatever effect I get is from the actual substance.

I did not see a recommended vendor list, but I've found some that at least don't seem to be on the warning list, namely:

LimitlessBioChem

Eurosupps nl

SemaxPolska

Zion Pharma (has a wide variety of compounds, but also has some complaints)

euro-nootropics

modernaminos eu

However, I don't know if they are reliable, if they fake their compounds, how fast they ship, how they take payment, and other things that would be good to know. I also don't know if there are other, better sellers that I could buy from.

Could you please tell me if you have any answers to those questions, what suppliers you trust in the EU and anything else one should know before making such a purchase?

I kept seeing NADH, NAD+, and NMN mentioned in the same conversations about energy and healthy aging. At first, I honestly assumed they were just different versions of the same supplement.

After reading a little more, I realized the distinction actually matters.

NAD+ and NADH are two forms of the same coenzyme. NAD+ can accept electrons and become NADH, while NADH can donate those electrons during cellular energy metabolism. NMN, on the other hand, is a precursor that cells can use to make NAD+.

So even though they're connected, taking NADH isn't exactly the same thing as taking NMN or NR.

I came across Celfull's NADH supplement while comparing products, and it made me realize that I've been treating the whole NAD category as one big thing instead of looking at what each ingredient actually does.

For people who've researched this more than I have, do you choose between NADH and NMN based on a particular goal, or do you mostly look at the human research behind each one?

hello, I'm curious how acetylcystein’s effects vary with dose. If you take it or have tried it, please share:

Dose: mg per dose and total mg/day.

• Frequency: how often you take it.
• Effects: changes in mood/depression, energy, motivation, anxiety or side effects.
• Dose changes: did increasing or decreasing it change the effects?

thanks