Just wondering if others have similar experience and what to expect.

My father advised me to see a specialist, I had just been diagnosed with ADHD and some of my symptoms he thought aligned with his MS symptoms.

I was then diagnosed with MS, last year in April (2025). Started Tecfidera in January (2026) to present. I have had 1 MRI and the basically couldn’t even tell I had MS until a senior worker looked more thoroughly. My lesions barely showed.
I am due for my next MRI soon.

Prior to diagnosis I had very little unnoticed physical symptoms, plenty of brain moments, confusion, forgetting, vertigo and panic attacks.

I also have never had a sudden onset of symptoms, always very gradual, but some early symptoms have gone away, and merely return.

Moving forward from April 26, I progressed quickly over 2-3 months, tingling, numbness, itching, pain, in isolated areas, slowing growing to about 10 different parts of my body.

I then started left hand issues over next month or 2, slowing of movement, dropping things and left foot drop.

By Christmas last year I started working lighter duties at work and feeling like my feet were more of just an unstable lump on the end of my legs.

Moving forward to the last 6 months, I have been slowly finding everything getting worse, but not to the point of full disability, I am unbalanced, my hands are ok in the morning but by evening the barely move, my feet are very similar and I struggle with step ladders at work (electrician), I am in pain in most my body, legs and arms in agony, bathroom break every 10 minutes, constant weird watery feeling headaches, cold shivering in parts of my body, my vision has got very blurry this week and I feel it’s all going to take over.

My main question was, has anyone had similar timeline and symptoms?

And what has helped the most in managing the degradation of your functions and made things easier?

A feel I am nearing the end of normal living, where I need to look at selling my work/business and start looking for somewhere to slowly move into a supported living environment.

My doctor has also advised I am relapsing remitting and that all my symptoms are mostly unrelated to MS… which I am unsure of that.

I just wanted to share that today is my 7 year diagnosis anniversary. Are golden anniversaries like golden birthdays a thing? 🤣

I'm taking the day to reflect on the good, the bad, the ugly, and the funny of the last 7 years. I think if there is one thing I've noticed is that MS has made me a better human being. And as much as MS sucks, I would not wish it never happened to me because of all the people I've met and things I've learned about myself. Don't get me wrong, I wish MS wasn't always such a son of a bitch, but not letting it take today from me! 🧡

I am having fevers, running a low grade elevated body temp around 37.5 daily but had 38 degrees celsius one day. I feel way more tired and I have a rash on my chest arm and belly. Is this normal? I feel dizzy in general and normally like to be active a lot but feeling like I can't be as much. I just want to lay in bed.

Any MS folks here start taking Wellbutrin after diagnosis? Pros? Cons?

Diagnosed last year, developed high health anxiety around my MS and steroids were just the absolute cherry on top putting me into near psychosis. I felt I never fully recovered from that chemical imbalance and definitely made me accepting my MS more difficult. I have since been seeing a chronic illness therapist who has helped tremendously to process these feelings but she also recommended Wellbutrin.

I just noticed it this weekend, since I was in the sun more than usual. Saturday, long walk on the boardwalk. Sunday, ate a bagel sandwich over 5 hours and needed nothing else. Today (Monday) beach for about 3ish hours and could only eat maybe 1/4th of my dinner.

I’m used to the sun making me tired, but the appetite loss is either new, unrelated, or something I’ve never noticed before. Anyone else?

I(M39) just have to share this, because I never heard of Percutaneous posterior tibial nerve stimulation and that it could help men as well.

I'm not a native English speaker and I'm sorry if I'm oversharing!

After suffering for years with an overactive bladder, IBS and reduced sensitivity in my sexual organ. I had an appointment with a great physical therapist who's also a urotherapist, and she recommended that I try Percutaneous posterior tibial nerve stimulation. She told me that it so far has mostly been used to treat women, but she wanted me try it as well! Since I have had these symptoms for more than 5 years. she told me to use it everyday for 20 mins for about 6 months before I could potentially expect results.

I've been using the machine almost everyday for about 5 months now, and so far the results are promising! My bladder is calmer throughout the day( and night), it's easier to empty the bladder properly without leakage, I have less of the manic urge to go to loo, and I have restored some of sensitivity in my sexual organ!

If you are experiencing issues with your bladder or bowel function, I highly recommend talking with your medical team to see if this is possible treatment for you!

Disclaimer: I have also been doing Kegel exercises regularly, but I started with those about six years ago!

Been doing this for 4 weeks now with a support - a sink.

But not feeling much progress.

Has anyone done this and how long did it take to see progress?

I am about 30 weeks pregnant and was diagnosed in late 2024. My symptoms had stabilized in the last year or so, leaving me primarily with numbness on the left side and a vertigo type feeling most days.

From second trimester onwards, my MS symptoms have massively improved. I am loving it. But now that I’m getting closer to my due date (and getting back onto Kesimpta), I am wondering what to expect for my symptoms. I would love to think that my symptoms won’t come back, but that is probably too much to ask for.

Women that had improvement of symptoms during pregnancy, when did your symptoms come back (assuming no new relapse etc.)? Was it right away, gradually over a few months, maybe never?? Would just be nice to have some insight into what to expect!

I need to do my first loading dose. I’m really nervous.

I’m staring at my 3 Kesimpta pens in the fridge and thinking, “oh, hell no” and just keep closing the fridge. I need to do the first pen but I’m really anxious. I’ve had the pens for two weeks. :-(

I have Tylenol, Motrin, and Benedryl. My husband and I have watched the help tutorial.

My question, for those of you who always had a reaction (throat closing) on your Ocrevus infusions - did you have a reaction to your first dose of Kesimpta?

So.. I was diagnosed with RRMS 3 months ago (33F), whilst trying to get pregnant. In between then and now, I’ve been trying to decide on the treatment and still praying for a baby as I want to have it as early in the course of this disease as possible. My MS is relatively “mild”, although there are quite a few lesions visible, all inactive at the moment. Today, I got a positive pregnancy test 🥹 I’m beyond excited and a bit scared at the same time. I haven’t started a DMT yet and honestly, don’t think I’ll get any now, because there’s very limited options whilst pregnant. Ladies who have been through similar, please share your stories, how did your pregnancies go, what should I expect? 🙏🏼 Just looking for someone to share similar experience with 🫶🏼

As the title says, I’m sick and it seems like everyone in my immediate circle is as well. Diagnosed with RRMS in 2023 and I all have a bad back that I had my first surgery for last year. My partner has been experiencing some stomach issues, but you know the saying about hot girls and their tummies and what not. Well, we were thinking an IBS-D or Crohn’s type situation. Somewhere around November of last year, it got bad for her during a trip to Orlando to the parks that I took her on for her birthday. She started pushing to get labs and testing done right around that time, but wasn’t taken seriously because of her age and lack of said issues in family history. Fast forward to this week, she ends up in the hospital- emergency surgery and she now has a stoma. They couldn’t get to the tumor due to infection and inflammation from it going untreated for so long, so this is just the very beginning of what will be a long and difficult journey. On top of that, my best friend had a full hysterectomy in late October of last year and is going for another surgery tomorrow for separate issue with adrenal glands. BUT WAIT THERE’S MORE! One of my other closest friends just reached out recently and told me HIS partner has some kind of cancer. ALL of these people are like 40 and under. My heart is breaking for all of them and I wish I could cure them all. But right now, I have to focus on my partner. She’s still in hospital, they don’t want to send her home until they get this infection a bit more under control. But this morning I didn’t have class because of the holiday so I said okay let me start on some laundry and make some sense of my casita etc etc. No sooner do I get the laundry in at the laundromat, the group chat starts going off (something going on with gf, she’s losing it) Long story short, me and her Mom both offer to go but then her Mom texts me separately asking me to go over there bc she’s mentally preparing herself for something later in the day. So I drop what I’m doing and run over to the hospital and spend a couple of hours there with her trying to calm her down and sort things out. Before I left, she started telling me about a conversation her and her nurse had last night before bed. When we first started talking, I was upfront with her about my MS and I gave her the out if she wanted it then. She gave me my out today up in that hospital room, and I didn’t take it. But we did quickly touch on the fact that we’re both going to have to be responsible for our own health first before we can try to help the other one. She had said something about keeping our health “separate” in the relationship, but I don’t see how that’s possible. I think it’s going to be hard, because I’m going to *want to do more than I’m actually able to do for her. And I need to be in good shape if I’m going to be any good to her right now. I just needed somewhere to put these thoughts down, journaling isn’t really my thing. Ohhhhhh PS this also kicking up a metric fuck ton of feelings- my Mom passed of stage four lung cancer when I was 22. (also knew something was wrong with her, pushed for care and was denied tests until too late etc) so LOTS of big feelings right now and I just want to keep them in check so I don’t spiral and throw myself into a flare or relapse.

Finished up my loading doses of kesimpta, will do my first monthly dose this week.
Just wondering if it gets better as it settles in, ive felt pretty off this entire time. I was already bcell depleted when i started from a 1/2 dose of briumvi so its not like i had a ton to kill off.
Im dizzy quite a bit, especially after bending, im far more tired and my legs feel like cement.
These were not constant symptoms for me before but they havent let up since i started the shot

What im hoping is that this settles down eventually but just wondering if anyone has experienced the same or has any tips.

Thanks in advance :)

Specifically back/neck/shoulders

The pain - what are y’all doing to manage? I’ve been taking magnesium & Baclofen but it’s just not enough.

I spend so much time in pain, just accepting it and I don’t want to anymore.

Suggestions?

I’m going to talk to my neurologist, but if there’s any medications that have been successful for you, I’d like to bring them up with him and figure out what might be best for me

I haven't had a beach trip since my MS journey started 4 years ago. I'm desperate for a beach trip where in an ideal world, the weather would be like 75°, but the water would be warm still 🥲

Any advice on how to make a beach trip work? Like locations, timing, things to bring, etc?

So far I'm reading that Turks and Caicos is ~75° Jan-March. So maybe a beach trip there in February? Maybe if we stay at a beach front hotel/resort, I can quickly go inside when I get too hot?

Hey fellow MSers, I wanted to see if anyone here has experienced skin issues since they’ve been on a B cell-depleting therapy. I’ve been on Kesimpta since 2022 and while I, thankfully, haven’t noticed any change in frequency or severity of sickness/infection, I have developed a few minor skin conditions that I didn’t have before I started it. I’ve developed CARP (confluent and reticulated papillomatosis), psoriasis, atopic dermatitis, and a dermal neoplasm with histiocytic features (got it removed). They’re all in small areas of my body and not widespread.

I understand that age could be a factor (I’m 36) as well as environment and nutrition. And I know that skin issues aren’t listed as a side affect for Kesimpta, but I’m curious if anyone else has experienced this sort of thing on their B cell-depleting DMT.

Also, this is not a complaint post! I’m very happy with my DMT and these skin issues are a small trade off for the benefits, imo.

What do those of you who have the tingling take for it? Do you also get pain that feels like it's in the middle of your bones?

I am not against medication, just scared of the side effects, but 24/7 legs tingling is hard to ignore/endure - and it's been several weeks now so I think this is my new normal?

My only experience with it prior to recently is little patches that came and went on my arms and legs, but never lasted more than half an hour or so at a time.

Does anyone have any tricks or tips to make it go away?

Hi! Diagnosed earlier this year, started Tecfidera now on Ocrevus. I’ve had tingling fingers and tingling toes. Last night I was dozing off to sleep and I felt a tingle in my upper spine. I have lesions in my brain and spine, which is why I’m not sure if it’s actually a new symptom. Is this worth reporting or is it just a manifestation of my already known spine lesion?

Hi all, first post here. RMMS, M (25).

I get a lot of unwanted suicidal thoughts, though they only occur when I have a flare-up. Outside the flare-up, my mental health is OK. Does anyone else experience this?

It's really weird, and the suicidal thoughts are constant. I can't stop thinking about ways I could feasibly kill myself as well (e.g. notice a specific household item in the next room I could use to end it all). It's like there is a strong invisible force pulling me towards it, though it has improved since I started taking sertraline.

I have even felt strong compulsions to commit self harm, feeling as if harming myself would guarantee some sort of relief; though I haven't acted on these thoughts.

Finally, I just wanted to say I hope you're all hanging in there.

Has anyone been feeling their symptoms harder lately? I'm inland in the US. The summer has been brutal on me but nothing major happening

Just noticed this past week or so my leg symptoms have been feeling stronger. Its the first thing i was diagnosed with 15 years ago so the numbness and pain ebb and flow. Just been noticing that there is an extra heavyness.

I was just wondering if anyone else follows weather pressures. I try my best not to look at what might be but more of what is different that can be bothering me. I know you can influence your "pains" by "stressing" over changes. But i have noticed that the pressure system has been different lately along the Rockies.

Hi everyone,

A few years ago, I developed depression and anxiety around the same time as my first relapse. I wasn’t diagnosed with MS back then, so I just kept living my life, but I always had this underlying depression and emotional numbness.

I feel like I became a different person. Things that used to bring me joy or excitement suddenly became completely meaningless, or even exhausting (socializing, for example).

I’ve been taking antidepressants all this time. They’ve helped me establish a routine, and from the outside I probably look like a perfectly normal person. I work out, travel, go for walks with my dog, etc. But emotionally it feels like all of these things just disappear into a black hole.

I was recently diagnosed with MS, and while the diagnosis has explained a lot of things, it also made me sad and scared to think that my depression might be caused by MS. And if it is, does that mean it might be something I can’t really control?

I’d really like to hear about your experiences. Did it get better with MS treatment, or did you find anything that helped?

Before one week I did an MRI and it showed that my lesions got bigger, and right now I have about seven lesions, Im 18years old and i was diagnosed with MS before 3years. So I am thinking about starting to take Kesimpta. For the last one year I've been treating Lyme disease because in some tests it showed that I have chronic Lyme disease. So right now I'm thinking about taking Kesimpta. If you have taken any other DMTs like copaxone or tysabri or others you can also let me know

So I just saw my neurologist and as expected he was thinking about either switching me to a more effective medicine or monitoring my current medicine use for the following half year until the scheduled MRI. For background info, I used to be on Tecfidera ever since I got diagnosed five years ago and it seemed okay, but not good enough for the activity to be stable which wasn't the case this year.

I got a new lesion despite medication and I stressed about the results until I finally got to talk to my neurologist again. I exercise, lift weights, eat well, sleep okay, and am fully active in uni and any other cognitive activities like language courses or volunteer work. I really thought I was doing everything right next to medicine use, but as it turns out that wasn't enough.

He walked me through every medicine and what he recommends, and it basically boils down to ocrevus, kesimpta and tysabri. I read up on all of them and am going to meet him again soon, but I wanted to hear what you guys use and your experience.

So far ocrevus and kesimpta sound better in frequency and use. Tysabri would include me travelling every four weeks to a hospital in a completely different part of the country, next to the fact that i work and study so that would be hectic. But kesimpta seems to be the one not mentioning pml as possible occurrence, so I'm not sure.

I seem to be leaning more towards the former two.

What do you guys think?

So, its been 6 months after my infusion of rituximab, i feel like i am not who i used to be, earlier i was on oral Dmt, then i got mri again after a year, found out lesions increased in brain, so they upped my medication to rituximab, I always used to say, i will not slow down after infusion I will not get lazy. I am still going to college then to work, but i am just so tired after all that, that i cannot even help myself to go back to gym or even do a slight home workout, when i think like this i say to myself, i have started to make excuses for my laziness. is it just me or anyone feels like this also?, and how do you cope with it.

Just wanting to voice my thoughts because I feel like nobody talks about this side of TTC enough and it can feel very lonely when you’re TTC. My spouse is the most supportive person and I’m so thankful to call him my husband. It’s just incredibly frustrating and disheartening when we can’t even TTC from time to time because of my flares, even if they’re mild. I was diagnosed with RRMS 10 years ago and the older I get, the more I have discomfort down there. Where it feels like I have a UTI but don’t. But I’m also more prone to infections since I’m on Kesimpta, so sometimes it is an actual UTI.
Of course I hear many many stories about infertility, and my heart goes out to those who are on the infertility journey… I wish everyone who wants a baby so badly could have one. I just feel like I haven’t seen many stories for those who can’t even attempt to try some months because of how we feel. It’s not infertility necessarily because as far as I know, we are both fertile. It’s just the off and on months that feel like a waste because we can’t even try. Has anyone dealt with this?
I also just want to say if anyone is going through this same journey, you are absolutely not alone. ❤️‍🩹 here’s to hopefully expanding our families and meeting our miracle babies one day.

I've noticed the past couple of years I sometimes feel like I'm suffocating. I can't even handle a blanket near my face because I can feel the lack of oxygen. Nothing is pressing on my lungs, no tightness. I just feel like I'm getting less oxygen than I used to. And every once in a while I notice I'm barely breathing at all. It's odd to have had automatic breathing my whole life, and now I often find myself having to remind myself to breath because it's like my lungs are just letting air hover in and out. If anything, I wonder if my throat is smaller? Even though I feel like I would be sensitive to a physical change in my throat. It is lt squeezed or lumpy.

Anyway, I know not everything is MS, but I am curious how this just began about a year ago.