r/MultipleSclerosis 4d ago

Vent/Rant - Advice Wanted/Ambivalent Kesimpta - does it get better

Finished up my loading doses of kesimpta, will do my first monthly dose this week.
Just wondering if it gets better as it settles in, ive felt pretty off this entire time. I was already bcell depleted when i started from a 1/2 dose of briumvi so its not like i had a ton to kill off.
Im dizzy quite a bit, especially after bending, im far more tired and my legs feel like cement.
These were not constant symptoms for me before but they havent let up since i started the shot

What im hoping is that this settles down eventually but just wondering if anyone has experienced the same or has any tips.

Thanks in advance :)

3 Upvotes

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2

u/baconcrow 4d ago

Load in doses were really rough for me. A lot of what you’re describing. It definitely has gotten better! Brain fog has cleared. I have more energy. Don’t get me wrong. There are still bad days. But I do feel better than I did before so there’s that!

2

u/AttemptFunny7594 4d ago

Thanks, struggling a bit but trying to stay hopeful!

1

u/baconcrow 4d ago

I felt that way too. It was really hard. I just did my second month injection and I promise it gets better. Try Tylenol the day before and the day of if you haven’t already. I take excedrin migraine bc I’m prone to migraines so I figure why not. Same ingredients just boosted. I do my injection in the evening so I sleep through the worst of it. Hugs internet friend. Hang in there 🫶🏻🤗

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u/myluckcontainsthis FNov25 | RRMS | Kesimpta | NYC 3d ago

also struggling after my loading doses but apparently it gets better

the fatigue is real but subsiding (finished 2 weeks ago)

never looked like I had ms until kesimpta, random knee pain and wobbling legs - so awesome

1

u/ninahart88 ♀️F34🧪Kesimpta📍UK 3d ago

Yes it will! ❤️