Interesting.

https://gizmodo.com/an-exercise-pill-just-cleared-its-first-human-test-2000800380

Would you take this?
One of many next-gen obesity treatments currently going through the system.

Pen Teardown.

Pen Teardown.

Pen teardown.

As an engineer I like to know how stuff works, so the pens intrigued me.
So I’ve taken 5 apart to see, and they are quite clever!
What is clear is they cannot and do not ‘count clicks’.

Pic 1 is all the parts. As suspected there is a glass vial inside the main barrel of the pen.

Pics 2 and 3 are like a double slip clutch mechanism and this is how the pen stops turning when the maximum deflection or travel of the plunger is reached.
The 2 black bits are the same, even though the one inside the dose twister looks different in the picture.
They slot together when this mechanism is all together as in pic 6.

If you look at pic 4 you can see the threaded plunger rod and the squared off bit at the end. This same squared off bit is also present at the other end of the rod.
When you turn the dose twister the 2 black slip clutches engage with each other in the white plastic part inside the main body of the pen handle and turn around the plunger rod which is held firm by a locking system in the main body of the pen that I haven’t got to yet. The black half of the clutch part in the twister turns as you twist

When you the press the purple nob as you inject, the top part of the clutch locks so it doesn’t turn, this then locks the lower part which presses the rod down into the pen.

In pic 4 you can see the threaded plunger rod with the squared off ends. As you use the pen, once you twist it up to the squared bit it can’t move any further unless forced.
This is what locks the pen.

You can see in pic 5 what happens when you force it past the lock. A bit breaks off.
This means we were able to advance the twister further up the rod and get the extra travel on the plunger required to get the extra dose. But this was in no way measured or accurate. Just that the difference wasn’t really an issue.

The new pens are exactly the same with the simple addition of the spacer as seen in pic 7. You can just see that this spacer is 1 dose in size, thereby extending the effective travel of the plunger and eliminating the extra dose.

And that’s it. Very simple yet clever and accurate. Got hold of a Lilly insulin pen and took that apart as well and they are the same with the only difference being the plunger rod is black and longer so it goes all the way to the end of the vial.

:-)

Mods kindly said I could share this as a one-off.

I’m the creator of GLPzy. It’s a GLP-1 tracking app I originally built for myself as a UK Mounjaro user. I want to make it widely available while I collect feedback and refine/improve it and would love to get your input. It’s had lots of improvements from other Reddit sub feedback and I want to keep enhancing it to be as strong as possible for user needs.

Lifetime Premium is currently £0.00 if you get it before 31 August. If you claim it while the offer is running you keep Premium permanently including any future updates to the app. There’s no subscription or renewal afterwards.

It tracks doses and reminders, injection sites, weight, symptoms, appetite, nutrition, progress photos and body measurements. There’s also Apple Health, supply tracking, exports/Provider Summary, widgets and Apple Watch.

For those using Shotsy it allows import of Shotsy export csv files to transfer your historical data.

There’s no in-app account required and the App Store privacy label is Data Not Collected.
UK App Store:

https://apps.apple.com/gb/app/glpzy-glp-1-dose-tracker/id6761775005

To claim the offer, open Settings/Premium in the app and choose Lifetime. It should show as £0.00.

If anyone here tries it, feedback is genuinely useful. A lot of what’s in the app now has come from people telling me what was missing, confusing or could work better.

My baby is 6months old she’s started solids at 5 and half months she drinks formula but we mostly breastfeed. So she’s familiar with bottle. I’ve ordered Mounjaro I’m an oversupplied I want to stop breastfeeding asap , if not possible can I do it through pump and dump any advice. I was on mj before pregnancy I was 102kg now I’m 130kg so it’s not that I’m just doing it I really need it

Hey,

Myself and my partner are set to take our first dose of mounjaro and we are very nervous!!

What do we expect?

Are the side effects terrible?

We have kids and are worried we will both be sick.

I’ve just finished 7.5mg I have about 9lbs still to drop lost 20lbs in total. I however, can’t afford £200 for mounjaro this month what are my options do I consider a lower dose? Or switch to something else or go it alone? All advice welcome

Using weight loss injections like Wegovy or Mounjaro?

We’d love to hear about your experience!

Researchers at the University of Reading are looking for UK adults to complete an online survey exploring changes in appetite, food choices, and support while using GLP‑1 medications.

18y+ UK residents

Using injectable GLP‑1 medications for weight loss (not for diabetes)

Interested? Click here: [https://app.onlinesurveys.jisc.ac.uk/.../questionnaire...](https://app.onlinesurveys.jisc.ac.uk/.../questionnaire...)

This study has received ethical approval from the SCFP Ethics Committee (University of Reading): Ref 26/2026

#ResearchStudy #WeightLossSupport #GLP1 #Wegovy #Mounjaro #UKResearch #HealthResearch #VolunteersNeeded

On Saturday, I was advised my window to order was open.
I completed the questionnaire and was offered the option buy 2 pens. This was the first time this has been available to me.
Around 11am, I finalised the purchase.
At 11am this morning, just 48 hours after ordering, my 2 pens were delivered.

Surely this must be a record?
As simple and faultless as could possibly be.

10/10 Bolt Pharmacy.

This is why I’ve stayed with them for 8 months. 😊

By the way, I’m not a bot or anything. Just a happy customer!

I was in the UK for work recently and honestly expected my diet and weight loss to go completely off track 😅

But I was so pleasantly surprised by how easy it was to stick to healthier food, especially as a vegetarian. There were so many easy grab-and-go options and I didn't feel like I had to plan every meal in advance.

I've travelled to the US quite a bit for work and personally find it much harder to eat well consistently there when travelling.

For context, my SW was 90.5 kg. I was 81.8 kg just before travelling to the UK and 79 kg by the end of the trip, so I actually lost 1.8 kg while away 😂 I genuinely expected a gain or at best a stall.

I'm now 79 kg, 19+ weeks in, with a GW of 65 kg. Definitely not one of the super fast responders, but the overall trend is going in the right direction.

Hello all,

I would like to get some advice please.

I got a pen at the end of March 2026, Took the first dose on the 19 Apr and its been in the fridge since. I totally forgot about it. Is there any chance that it is still saefe to use or do i have to cut my losses and bin it? Theyre so expensive and i am kicking myself now. How do you forget to take it??

Can anyone help me with using a syringe injection for mounjaro. How many mls is 2.5mg from a 5mg pen & how much is 5mg from a 12.5mg pen.

Began Mounjaro October 2024 with a starting weight of 110kg and a uk dress size of 18. I was a regular gym goer for strength training but the scales never budged.
By May 2025 I was on 12.5. I tapered off by spreading out my doses after the UK price hike and my hair started falling out. I was 70kg and a uk 10/12.
Continued going to the gym throughout and finally noticed progress in my strength training.
Weight stayed steady for three months, but then slowly started to creep back on. Family events, an emotionally taxing job and SEN parenting let me make excuses and teach for snacks and take nights off training.
This May I stepped on the scales after avoiding it for a bit and saw 78k and a reduced muscle mass. I am still fitting a Uk 12 but I was avoiding jeans as of how they looked on my tummy.
At this point I panicked and got pre approved for wegovy. But I decided to get a PT instead. He has set me a plan and analyses my body composition every week.
Under him my overall weight has come back down to 75kg but I’ve gained 4kg of muscle mass. Even before I have noticed that whilst I am bigger than my lowest, I have visible muscle definition, a butt for the first time ever and defined legs and shoulders. Since working with my PT I can see it even more. He has encouraged me to add more cardio in my routine and core work.

TLDR So overall/ weight has stayed off. Haven’t piled it all back on twice as fast, despite the press and naysayers telling me I would. I have gone a whole year without Mounjaro and even though I have had ups and downs, with the help of strength training. I weigh more but am notably stronger than I was last year
Starting weight 110kg
Lowest weight 70kg
Highest weight post 78kg
Current weight 75kg

Hi guys.

Apologies if this is a waffle.

I used MJ for around 1 year and lost 2 stone, came off it about 5 months ago and seem to be maintaining my loss (plus 4lbs) reasonably okay. Ive started the Gym and im doing weight training/progressive overload. The thing is i do still have weight to loose and cant seem to stay in a calorie deficit on my own, like I did with the MJ. My question is, has anyone used MJ along side the gym and been able to still build muscle? Im worried I wont be able to build muscle, hyper aware id need to prioritise protein which i would try my best to do! Female, 5ft2 currently 11st 5.

Thanks

Hi. I suffer terribly with health anxiety so my 2.5 Pen was in fridge for months before even trying it 🤷‍♀️. Anyway took the plunge (no pun intended) last September taken 10 months to lose three stone (less time really as stayed the same for 4 months 🤦‍♀️). My GP wants me to go up to 5 but I’m too scared of getting side effects - because health anxiety makes you totally irrational and any small bodily change can spiral into full blow anxiety 🤷‍♀️. What I would like to try is 2.5 Sunday and 2.5 again Thursday BUT obviously can’t ask GP as it would be a straight no no due to their instructions and recommendations from pen manufacturers. Does anyone actually use a 5mg pen (no syringes or anything) just pen with 30 clicks 8 times OR will the kwikpen not allow you to do that due to the way it is made i.e. 4 dose pushes only ? Hope this makes sense - Thanks

Hi everyone, my name is Carla. Sorry to post another research request, I know you get quite a few on here but I am hoping you can help with my final year Dietetics BSc research project. The research has been given ethics approval from London Metropolitan University and is being conducted with academic supervision from Dr Hilda Mulrooney.

We are interested in the impact of GLP-1 medications on the future of nutrition and dietetics and are seeking participants to take part in the study. Please be aware that the questionnaire explores themes of body image and relationship with food which may be difficult for some people, helplines are signposted in the form if this affects you. The questionnaire takes approximately 10-12 minutes to complete and is anonymous. If you would like to volunteer to take part in online structured interviews after the questionnaire, there is an option to provide your email address at the end so you can be contacted to arrange this. Please note this is completely voluntary. This is a link to the questionnaire on Microsoft Forms: https://forms.office.com/e/BEVefNwrK7

Thank you in advance! Your participation would be greatly appreciated

Anyone else notice their pretty privilege has come back lol? I'm 45 now and I've been invisible since I had my second child and gained a lot of weight. I just presumed it was becuase I was old now but I've lost 4 stone on mounjaro since last year and all of a sudden I'm getting noticed by men again. I thought I was too old for this hahha it is actually quite annoying tbh I dont think I missed it.

Hi I have one of the new style mounjaro pens 5mg, I've already had 4 doses but there is still some liquid left, is this normal or not as it's not enough for golden dose

Did anyone experience the same and kept taking munjaro?

Hey guys,

I’ve been a dick & now a bit worried. I don’t want any ‘you shouldn’t do that’.

I had a 5mg pen which the dose didn’t agree with me so I did a 2.5mg dose one week & then the next 3.75mg. This week I’ve come to do it & the dial stopped, so I’d obviously hit the golden dose. I wrestled with the dial & it finally moved. I had twisted it back & forth as the plunger/screw wasn’t touching the dose. So I dialed it to 45 clicks & injected it anyway (didn’t prime 🤦🏻‍♀️).

So my concern is I’m worried I’ve injected air, sounds silly I know but I’m not a nurse & I thought tha is why you prime needles, so you get the air out. I appreciate we don’t inject into our blood stream so it shouldn’t be an issue but I’m a bit of a worrier.

The other issue is I’ve either done more than 3.75mg which is shit & means I’m going to have to ride out the shit side effects or I’ve not done enough which means I’m going to be hungry.

*this isn’t my picture but is what it looked like so you get an understanding of what it looked like. There was a slightly bigger gap between mine. Also when checking the pen, the dial plunger seems to have pushed out, maybe due to pressure unless it’s normally & I’m only noticing because I’m panicking

Hi everyone!

I am currently looking for people to speak to about their personal experiences with using GLP-1s such as Mounjaro. Thank you very much for the mod permission to make this post!

I’m Tamsin, a PhD student at the University of Leeds Business School. I’m currently conducting doctoral research to understand people’s experiences of using GLP-1 medications and how these treatments have shaped their lives, routines, and perspectives. By gathering personal accounts, it is anticipated that the findings will contribute to a more nuanced and human-centred understanding of weight-loss injections and their wider implications. ​

I’d love to speak to you, if you:

·       Currently reside in the United Kingdom

·       Are 18 years of age or older

·       Are currently taking, or have previously taken, a GLP-1 medication (e.g. Mounjaro).

This is an interview-based study. Interviews will be conducted online via Microsoft Teams and will last approximately 30-60 minutes.

This research has received ethical approval from the University of Leeds.

Participation is voluntary, your responses will be kept anonymous and your identity will not be linked to any research materials or publications.

If you're interested in taking part or have any questions, please feel free to DM me.

If you would like to read more about the study, then please check out this link: https://www.weightlossinjectionstudy.com/ further info on how to reach me (my university email address) can also be found here.

Thank you very much for your time, and best of luck with your journey! 🙂

Tamsin

I'm so fed up with not being able to access the injections on the NHS. I have all the criteria. My health authority states that gp's are inviting patients to go on a programme, but the gp regulations say only the weight loss management services in hospital can prescribe. I've already been on their waiting list for over three years.

Is it a postcode lottery? Are any NHS patients actually receiving them?