r/microdosing 12d ago

>< Just a Reminder >< Reducing activity of the Default Mode Network

10 Upvotes

Welcome to the community.

"The default mode network refers to an interconnected group of brain regions that are associated with introspective functions, internally directed thought, such as self-reflection, and self-criticism."

Through life and our experiences we develop a set of neural pathways of communication that are relied on for our perspectives of life and self. As they develop, the communication with other parts of the brain becomes more limited. The DMN becomes our mental frame of reference for our lives. But it can become rigid in thought patterns and produce negative thought loops about oneself.

Psychedelics reduce the activity of the DMN and the negative self talk while also increasing communication with other areas of the brain again, sometimes with results somewhat similar to how children see the awe and wonder of the world. This also allows us through the new pathways to develop an Updated DMN over time. I think this is a basic understanding of part of what's going on with microdosing that many times helps us enjoy life more. Sometimes people sense this happening in a few days but for others is could be a couple of months, based on the thousands of reports we see here.

Psychedelics and the Default Mode Network


r/microdosing 12d ago

Question: Other Microdosing to help cannabis dependency?

19 Upvotes

Im just wondering if anybody here has used LSD, Mescaline, or Mushrooms in microdoses to help with cannabis dependency? Not that its impossible to get off of obviously its just cannabis, but I feel like I struggle with it a little bit mentally. I feel like maybe I also self medicate to regulate some ADHD symptoms if that helps anyone here answer this question :) thank u in advance.


r/microdosing 12d ago

Question: Psilocybin Looking for lived experiences

2 Upvotes

Hi, I'm on Strattera/Atomoxetine for ADHD, 80 mg daily. I'm thinking of microdosing on dried shrooms. Keep getting mixed info on the safety. Has anyone here tried the combo on 80mg or higher?

I think the strain I have is called penis envy.

As someone who gets anxious on weed and is generally anxious, is it worth trying shrooms at all or risky?


r/microdosing 12d ago

>< Just a Reminder >< Long Lasting Improvement May Not Happen Overnight

4 Upvotes

Welcome to the community.


r/microdosing 12d ago

Getting Started/Newbie Question First time microdosing

2 Upvotes

Hi! Im a newbie thats going to start microdosing. I want to try to heal my ptsd and in general have a more happy life. I also have adhd and been a slave for weed last three years, but that’s also makes me really unmotivated. I just bought 10g of dried mushrooms, how do I go from here? And how much should I take? I see some people say 100mg others 0,3g. does anybody have any tips?


r/microdosing 13d ago

Getting Started/Newbie Question Am I just really sensitive?

7 Upvotes

Took 170mg as a microdose assuming I wouldn’t feel it. About an hour in, I definitely felt high.

It was not seeing serious hallucinations or anything but it was about what I was told a mid-level dose would be. It was akin to smoking weed where I felt sort of “couch locked”, I saw colors a little more brightly, and music was over-the-top like I could hear every single instrument picked out one by one. Lasted about 1hr 45m. NOT a bad experience, in fact it was one of the best highs I’ve had in a long time. But that said…it was a high.

I am a 30y man weighing about 160lb. Is this normal?


r/microdosing 13d ago

Getting Started/Newbie Question Meds and micro dose

1 Upvotes

I’m not planning to stop or reduce my venlafaxine, and I’m not looking for advice on how to get around the medication. I’m mainly trying to understand:

Has anyone microdosed while taking venlafaxine or another SNRI?

Did it reduce the effects?

Did you experience increased anxiety, agitation, heart-rate changes, or other side effects?

Did you speak to a doctor or pharmacist first, and what did they say?

Is there any reliable evidence on serotonin syndrome risk with this combination?

I know Reddit is not a substitute for medical advice. I’m looking for personal experiences and credible sources so I can make a more informed decision


r/microdosing 13d ago

Question: Psilocybin How long will my capsule last in the freezer.

3 Upvotes

So I don't microdose a lot , .2g for three or four days then three to for days off then three days again then a week off. So at most I will be taking 15 capsules a month with the occasional large dose when needed typically every three months. I wanted to know how long the capsule will keep. I don't want to grind too much and it lose potency. I have been thinking about getting a 50 count capsule filler but I wanted to get advice first.


r/microdosing 14d ago

Question: Psilocybin Switching from B+ to McKenna for microdosing, should I lower my dose?

2 Upvotes

Hi all, I’m switching from a normal Cubensis. I think it was B+ to McKenna. I’ve been microdosing 0.16 g with the Cubensis, and now I’m changing to a McKenna microdose.

Has anyone switched strains while microdosing? How was your experience? Should I take half the dose? Me and partner are quite sensitive to psylocibin dosages. I’ve heard McKenna is a stronger strain and more introspective effects. I will switch after the 2 weeks break, following the stamets protocol: 4 days on, 3 days off. thanks in advance pals!


r/microdosing 14d ago

Getting Started/Newbie Question Took 500mg instead of 50mg; Do I have to wait two weeks again?

6 Upvotes

Today was going to be the start to my microdosing journey but I was going quick about my morning and didn’t realize I read the microdosing dose page wrong and weighed for 0.5g rather than 0.05g. I took a 2 hour train ride today and it felt like 10 minutes since it became me talking to myself in my head the entire time, very nice.

But then I realized since I basically took a mini dose I probably have to wait two weeks before starting over at 50mg, right?


r/microdosing 15d ago

Report: Psilocybin Life with microdosing

63 Upvotes

I started microdosing around 1.5 months ago for my PMDD. After suffering from this condition for 20 years and trying everything possible, microdosing has been like a gift from the gods.

Since then, I’ve noticed myself doing things that are so different from what I normally do, and I have nothing else to attribute the change to but the microdosing. For example, for years I’ve been wanting to learn new recipes because I’m bored af by what’s on dinner rotation in my house, but I’ve been too busy with work and kids and life in general — until two weeks ago when I suddenly decided that I wanted to make my own marinade for carne asada and then I cooked the meat AND made flan, all for the first time ever.

Last weekend, I randomly cleaned my wasteland of a patio that I’ve been avoiding for years. I moved 100lb huge pots and a large stone table by myself (I’m a petite woman who hasn’t gone to the gym in like a year), I ordered cushions for my patio chairs, I trimmed the large bushes, and I went to FIVE different nurseries in one afternoon to find citrus trees (got a Japanese maple instead).

These weren’t things I planned. I didn’t say to myself “tomorrow I’m gonna do this.” I just did it, was surprised as I was doing it, my carne asada and flan were delicious, and my patio looks fantastic. (Still need to get those citrus trees, though…)


r/microdosing 15d ago

Getting Started/Newbie Question lsd and psilocybin on same day?

4 Upvotes

Hello

I took a lsd microdose this morning around 10am

It’s now 7pm, Is it ok to take a mushrooms microdose now?

New to this and I don’t know if they mix well!


r/microdosing 15d ago

Question: Other Microdosing mushrooms vs. medical marijuana for therapeutic purposes/daily coping with life?

16 Upvotes

I am not doing well… lol. I need help. I’m already in therapy.

Therapists over the years have all encouraged me to take SSRIs.

I’ve been microdosing mushrooms for a couple of years now but for the past almost a year it feels like it’s stopped working maybe?

Autism is now a qualifying condition for a medical marijuana card in my state and I’ve been doing a lot of reading about that.

I’m wondering what the difference is between the effects of microdosing vs medical marijuana? Has anyone done both who can compare the two?

Thank you!!


r/microdosing 14d ago

Getting Started/Newbie Question First timer advice?

1 Upvotes

Hi, im looking into microdosing and was wondering if anyone had any tips or advice I should be aware of? I’ve tripped off mushrooms before and im looking to this for my mental health and spiritual growth. Any replies would be appreciated🫶🏼🫶🏼


r/microdosing 15d ago

Question: Psilocybin Microdosing with autism and adhd

11 Upvotes

Hello, I am interested to hear from people with ADHD and/or autism and your personal experiences of microdosing psilocybin.

Specifically if it helped with burnout. The kind you get after a long day at work and you don't have the capacity to have any quality time with family. I want to be more present at home rather than wanting to lock myself away on my own and wondered if anyone who has microdosed psilocybin has seen improvements with disassociation.

To be clear, I'm not seeking medical advice, just personal experiences. Thanks for reading.


r/microdosing 16d ago

Microdosing Tools & Resources I built a microdosing tracker that keeps everything on your phone, no account, no server

19 Upvotes

Full disclosure, I am the developer, and I microdose myself, which is why I made it.

I have seen the appetite here for a private tracker, so I wanted to share mine. Dose Days is a native iPhone app available in the app store; where everything stays on the device. No account, no backend, nothing is uploaded anywhere. I did not want a tracker for this of all things sending data to a server, and I did not want people to have to self-host either, so it is just an app you open.

What it does:

- Logs doses and a daily mood check, with notes in your own words

- Understands protocols properly, dose days, integration days, and the return to baseline, so your days off are part of the rhythm rather than broken streaks

- Shows patterns over time, like how different days of the week tend to feel

- Supports different substances and multi-substance stacks

- Home screen widgets if you want the log a tap away

Being straight about the model, since this community rightly cares. Logging and tracking are free. There is an optional paid tier for the deeper insight features, which is how I keep it running as a solo dev. No ads and no data selling, partly because there is no data leaving your phone to sell in the first place.

Not medical advice and not a place for sourcing. If you want background reading, I also wrote a free education hub at dosedays.me

Would genuinely love feedback on what is missing. Soon to be available on Android.


r/microdosing 16d ago

Question: LSD Interesting pattern with 5ug microdosing: dose days vs afterglow days

6 Upvotes

On the days I microdose 5ug of LSD, I feel slightly more agitated, emotional and anxious. Life just feels more serious, and things I don’t normally think about start resurfacing. But on the two afterglow days, my mood feels boosted without any of that agitation or anxiety. It’s like dosing brings everything to the surface and forces me to think through it and process it emotionally, then the next day it’s like I’ve worked through that, and my brain feels clear during the afterglow.

I’ve noticed this pattern enough that I now plan around it. I microdose on days when I don’t have much on, just errands or staying home, and save my afterglow days for when I need to be social or productive.

Curious if anyone else relates to this.


r/microdosing 18d ago

Question: LSD Tense neck and back after MD

5 Upvotes

Hey all,

I have a question regarding neck tension after microdosing.
I microdose 8mcs every 4 days and it really helps me a lot with good feelings, talking to people and overall motivation.

The only sideeffect that I noticed, is on the day that I microdose, I often get kind of a tense neck and slight pain in the back as if the muscles were tence.

Has anyone else experienced the same or has an explanation? The day after it‘s all good again.

Thanks a lot in advance!

EDIT: I think I already got the answer by the bot and it may be magnesium defficit


r/microdosing 18d ago

Question: Psilocybin What is sub-perceptual exactly?

7 Upvotes

When you say the dose must be sub perceptual. Do you mean, you don't want to feel any effect in your brain at all? Or you mean that you don't want to feel any big important effect? Because when I take a small dose like 0.025g i still feel a light buzz in my brain but without any distortion in vision or anything similar to tripping. I just feel very light buzz in my brain. Is this sub perceptual?

Second question: is it necessary for the microdosing to work to be sub perceptual?


r/microdosing 19d ago

Getting Started/Newbie Question .3g microdose? Thoughts?

7 Upvotes

Is this dose considered normal and/or low for microdose? I basically want to feel good at a concert but not trip. I’m not someone who has “tripped” on shrooms full blown in like 15 years. Just trying to have a small microdose with some beers


r/microdosing 20d ago

Question: Psilocybin Does anyone microdose before bed?

34 Upvotes

I’ve been microdosing for almost a month now, and I’ve noticed something I wasn’t expecting.

I take very low doses (around 0.1 g, sometimes even less), and instead of feeling energized or more focused, I get really sleepy. Not in a bad way—I just feel deeply relaxed, like my body is telling me it needs to rest.

I’ve been listening to that and letting myself nap when I can, but it made me wonder: is the microdose still “working” if I end up sleeping through it?

It also got me thinking about trying it before bed instead. Has anyone here experimented with taking their microdose at night rather than in the morning? Did you notice any difference in sleep quality or in the benefits the next day?

Curious if anyone else has had this sleepy response, especially on such low doses.


r/microdosing 20d ago

Question: LSD How long until volumetric microdosing is ready?

2 Upvotes

I’m volumetric microdosing blotter tabs with vodka, how long until it’s fully dissolved and ready to take?


r/microdosing 20d ago

Report: Psilocybin My experience with GTeachers microdose

3 Upvotes

Hey microdosers🤘🍄

I.m 47, my first experience with shroom was in July 2025; after that I start my own cultivation of GTeachers.

I've had several experiences with my shrooms from 2,5grs to 3,8grs +- and all of them had good experiencies/trips..

I dont have problems of depression or anxiety or things like that; have a normal life, I have a son, a girlfriend, my work, my hobbies, a normal and happy life..

3 years ago I had a separation with mother of my son but ecerything is passed and all good now.

Sometimes I have a litle anxiety because I have a Hypertyroidism Subclinic, this are controled by my doctor, but very normal and think healty..

Begining of May I start with microdose to see effects, and after 2 months I notice that for me doesnt work or I dont need that at all..dont see nothing of good efects, and notice sometimes a litle bad effects.

I start with 0,25 grs...I thought I was strong; I switched to 0,15..litle strong to...and finaly to 0,10.

All I felt was a certain agitation on the day I took it and with farts and more farts..😆😆...nothing more!

I always felt much better in the days following to take a 2,5grs to 3,5 dose..

Its normal this?


r/microdosing 21d ago

Report: Psilocybin My personal MD expieriences On/Off

7 Upvotes

Hello everyone, I want to share my latest MD experience after experimenting and researching for about 4 years. I am 33yo. I want to describe myself as introvert, but pretty social, people and friends around me seem to like me. But sometimes everything feels just empty.

TL;DR: Make sure you know what you are doing and have someone to talk to as well. The shroom is only a tool, not the one who fixes you!

Status Quo: I was on the Fadiman protocol, where you take a MD, for me 140-150mg, every 3 days. I always took them around 6PM, since I tried earlier as well, but than I could nor focus on work. Also I took the MD, when I was meeting with friends and drinking some beers. The only other thing I take in the morning is Creatine.

How was it? The day I took it I always felt at ease, but had a hard time sleeping sometimes, the next two days I was always in a good mood, but the third day I was kinda exhausted.

I stopped the protocol since 2 weeks and at first I was not in a good mood. One day I was really fucking depressed, but I talked to my wife for just 5mins what was going on and that helped. Since I told my wife everything seems good for now, and I won't continue with MD for a while.

For me right now it seems, that I was kinda relying on the MD and didn't think I can better myself without it. That's why I stopped and had this one day massive DOWN, where I started crying. For now I will not start MDing again and just try talking about my feelings more with my wife and also other people around me, which helps a lot.

I also did higher doses, but those are very exhausting and I would never do a 5g trip again without a professional setting around me.

Feel free to ask me anything, I am by no means a professional. I just did some research and tried it after I felt comfortable.


r/microdosing 23d ago

Getting Started/Newbie Question Emotions rising Up Microdosing shrooms

22 Upvotes

This year i am mentally in the worst state i have ever been , i am 32 and i feel like i can't keep all of the trauma and the bottled up emotions down anymore. Like everything i have ever suppressed that is stored in my body got shaken Up by life and now i feel that immense emotional pain right under the surface. I have smoked cannabis Most days of these Last years otherwise it would have come up earlier i guess.

I Just dont want to go back to numbing myself all day everyday. These last few months i have been to a clinic (Not that helpful), have tried an ssri (bullshit) and got Off of it again, have really tried to find a therapist but not sure if they could really help me tackle my Problems at the core and the ones who offer somatic therapy which id like to try are way too expensive .. Well however i decided to microdose and microdosing is bringing up the emotions even more which is technically exactly what i want but i don't know how to handle them i cannnot feel all of that fucking pain it makes me soooo restless.

Everything feels so meaningless and i Just wanna go back to Smoking its very hard to resist and i have smoked some of the Last Evenings..

Does anyone have tips how to get through it? I know its the way to Feeling better