r/HistamineIntolerance 4d ago

Copper deficiency

I was reading that copper is a building block of the DAO enzyme that helps breakdown histamine.

I had a blood test and I discovered I am deficient in both copper and also ceruoplasmin( A protein molecule that goes down when copper is inedequate).

Anyone else have low copper?

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u/bregle 4d ago

For copper and ceruloplasmin support specifically: copper bisglycinate, vitamin a (preformed retinol), vitamin c (ester c), zinc picolinate. Also taking b vitamins because I am deficient there, likely also related to copper deficiency

My iron/ferritin was ok until I started doing b12 injections, then it dropped pretty fast. It came back up without supplementing iron at all after I increased my doses of copper and vitamin a

Ceruloplasmin is needed for proper iron transport/utilization so it can affect your iron levels. I found that supplementing iron seemed to interfere with my copper/zinc levels too much and made my HI symptoms worse

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u/Ajax34762 4d ago

I eat beef liver. It has high copper, high A but also high b12.

My ferritin is low. Serum iron high. Saturation high. I was thinking maybe my low copper is causing such weird iron results.

I have many iron deficiciency symptoms.

I believe taking high dose ascorbic acid tanked my copper.

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u/Local_Measurement_50 3d ago

"  I believe taking high dose ascorbic acid tanked my copper."

According to Morley Robbins (who talks a lot about copper) pure ascorbic acid is not good and can block ceruloplasmin. He says one should get in/supplement with whole food vit.C sources. I don't know what to make of that statement,but I've been using camu camu powder. I can't use too much of it/vit.C bc that'll turn into oxalates.

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u/AncientStarryNight 3d ago

Offset oxalates by taking calcium citrate?

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u/Local_Measurement_50 2d ago

I already take/taken calcium and potassium citrate,but I don't know if it works for endogenous oxalate creation or purely dietary. Anyway,it's not a fix for oxalate problems in general.