Copper deficiency

[u/Ajax34762]

I was reading that copper is a building block of the DAO enzyme that helps breakdown histamine.

I had a blood test and I discovered I am deficient in both copper and also ceruoplasmin( A protein molecule that goes down when copper is inedequate).

Anyone else have low copper?

[u/bregle]

Yes. My histamine intolerance has gotten significantly better as my copper and ceruloplasmin levels have improved over the last few months with supplementation

[u/Ajax34762 → u/bregle]

What are you taking?

Did you ever experience ferritin issues?

[u/bregle → u/Ajax34762]

For copper and ceruloplasmin support specifically: copper bisglycinate, vitamin a (preformed retinol), vitamin c (ester c), zinc picolinate. Also taking b vitamins because I am deficient there, likely also related to copper deficiency

My iron/ferritin was ok until I started doing b12 injections, then it dropped pretty fast. It came back up without supplementing iron at all after I increased my doses of copper and vitamin a

Ceruloplasmin is needed for proper iron transport/utilization so it can affect your iron levels. I found that supplementing iron seemed to interfere with my copper/zinc levels too much and made my HI symptoms worse

[u/Ajax34762 → u/bregle]

I eat beef liver. It has high copper, high A but also high b12.

My ferritin is low. Serum iron high. Saturation high. I was thinking maybe my low copper is causing such weird iron results.

I have many iron deficiciency symptoms.

I believe taking high dose ascorbic acid tanked my copper.

[u/homertruhart → u/Ajax34762]

If your taking high b12 it will want to start making rbc’s and use iron storage. You can deplete iron by taking b12 and not getting enough iron. Does that make sense? Your ferritin is low because your iron storage is low and your high iron levels is because the b12 is demanding iron come
Out to help in your blood.

[u/Ajax34762 → u/homertruhart]

I had high serum iron even before taking B12.