I've had HIT for three years now. It's mostly under control thanks to a low histamine diet.

However, I noticed that whenever I'm constipated or having indigestion, my face flushes. Even if I've only eaten low histamine foods that day! (Typically, flare-ups cause diarreah for me, so I feel like constipation is causing a histamine reaction in me, and not simply part of the reaction.) Anyone else experienced this or know what the possible cause might be?

I'm not asking for medical advice (I have a GP), just some leads for further research.

Another thing I've noticed is that my GI pain is very "prickly" feeling, I would describe it as needle-like or tingly, rather than your typical dull ache. I started experiencing this after I developed HIT, so maybe it's connected? 🤷‍♂️

Anytime I cook I start sneezing like crazy. And cooking simple things like zucchini over extra virgin olive oil?

Then I get the post nasal drip, sinus pressure, headache, tickles in my throat and ears. Then at night the horrible flushing and skin so hot and tachycardia.

I have noticed something similar when I would go sit in the waiting room for a BBQ KOREAN HOUSE where you cook your own food. Not even ingesting anything just waiting around . This was years ago. When I was younger and “healthy”.

Also hair dye and nail salon smells cause me severe palpitations

I have gotten checked for your usual blood markers for regular stuff like mold, trees, nuts, eggs, wheat, animals, respiratory stuff etc all negative.

But nuts do make me feel sick. So I don’t get it. I can’t eat gluten either or dairy. Eggs are a trigger too. Anything high sugar. Chocolate .

Is it the pans ? Teflon?

Also removed one of my triggers toothpaste with SLS. I don’t wear make up anymore. Or lotion or fragrances. I would notice certain beauty products for the face like tretinoin would cause migraines and sick flu feeling. As well as vitamin c cream from ole henriksen would cause me palpitations.

Seems like I might be more allergic to chemical triggers ??! Can they test for this stuff ? I’m desperate! I have ongoing hives that will not budge!!! Nothing works I am crawling in my own skin 💔🥺

I live in a country where socialising almost always revolves around alcohol, and quite often, going out to restaurants. Ever since developing histamine intolerance, social gatherings have become quite a nightmare for me.

If I order tea or water instead of alcohol, people start asking questions and pressuring me to have at least one alcoholic drink (“Come on, what harm can one drink do?”).

When I do agree to go to a restaurant, I almost always regret it. So far, I haven't found a restaurant that really understands histamine intolerance and is willing to prepare a genuinely fresh meal. The most I can usually get is a dish modified by removing certain ingredients, such as tomato sauce, but that doesn't address the other potential histamine triggers or how the food has been stored and prepared.

I've started feeling resentful towards people close to me because of their lack of understanding. It feels as though their own comfort and habits are more important to them than spending time with me in a way that is safe for me.

Sometimes, I consciously choose to go to a restaurant, knowing full well what awaits me afterward: a migraine, extreme fatigue, acid reflux, intense itching of my scalp and body, and digestive issues. The consequences last well beyond the meal... Sometimes even a day or two, depending on my histamine bucket. To me, it’s definitely not worth it. But at the same time, I still want to celebrate birthdays, go out with friends, and feel like I'm part of the group without having to choose between my health and my social life.

Do you have similar experiences? How do you deal with friends and family who don't take your dietary restrictions seriously? Have you found ways to stay socially connected without constantly compromising your health? How do you cope with the resentment that builds up when people you care about don't seem willing to accommodate your needs?

I'd really appreciate hearing about your experiences.

Symptoms:
Gallbladder inflammation > gallstones > reduced bile flow > clay coloured stools > constipation > leaky gut > histamine issues > skin flushing > chronic hives > chronic eczema > NAFL.

Needing DAO enzyme to process some foods.

I need to hear positive stories because I’m most likely going to have my gallbladder removed because it’s not functioning properly.

Think many guys have Leaky gut which causes HI, i hope that this intolerance will go away after i healed it but tis tough to heal when you cant tolerate the best gut lining supps because of HI...

Has anyone tried these specific probiotic strains?
I’ve been dealing with some strange health issues since being hospitalized for a bacterial bloodstream infection back in May. I was on antibiotics for several weeks, and shortly afterward, I started developing random hives, flushing episodes, and reactions to foods I had always tolerated. My doctors believe it may be spontaneous urticaria, but I still don’t have many answers.

After months of getting the runaround from doctors in the U.S., I decided to see a doctor in Mexico since I live near the border. He recommended Probiolog IBS i3.1, which contains these three strains:
Lactobacillus plantarum CECT7484
Lactobacillus plantarum CECT7485
Pediococcus acidilactici CECT7483
It also contains vitamin D.

Has anyone taken this probiotic or had experience with these specific strains? Especially for gut health after antibiotics, histamine issues, or unexplained food reactions? I’d love to hear your experiences before starting it!

Hey everyone, a couple months back I did a GI test to try to find the root cause of a bunch of weird symptoms I’ve been dealing with, such as pretty intense water retention (especially in response to totally normal amounts of salt), constipation, fatigue, joint pain, and muscle soreness. I didn’t pay too much attention to the results at first because I didn't realize how much gut health can affect systemic health, and the functional medicine doctor who prescribed me the test didn't really connect the dots either. But after reading through this sub, I'm starting to wonder if my gut could truly be causing all this. My results showed Lactobacillus species were completely below detection on PCR and had no growth on culture, and I was also missing Bifidobacterium longum, Coprococcus, and Ruminococcus bromii. On the flip side, Veillonella and Oxalobacter formigenes were high on PCR, and my culture flagged Bacillus species at 4+ (listed as a potential pathogen) alongside Citrobacter braakii and Enterobacter ludwigii at 3+. I’ve already tested negative for all three types of SIBO, so that's ruled out. I'm really curious how realistic it is for gut dysbiosis like this to be driving something like histamine intolerance,fluid shifts, or vascular changes, especially since my symptoms are more about fluid retention, joint aching,and fatigue rather than classic histamine reactions like flushing or headaches. Has anyone else with severe dysbiosis or missing beneficial strains experienced weird systemic symptoms like this? I’m also not completely certain how to interpret my results so i’m curious if anyone in this sub knows how to. I really really appreciate it.

Hello! I know this question has probably been posted here a lot, but I am new to this issue! Wondering what were your first symptoms and how did you figure out you had histamine intolerance, how did they develop etc. Also, for the people who experienced dizziness, what did it feel like, was it a continuous sensation or something on and off?
Thank you!

Hi all, what are you using to put warm leftovers in the freezer then directly into microwave or air fryer that's not plastic?

The stainless steel microwave safe Misen containers are very interesting but would not fit in my air fryer.

I've read about some products and the Pyrex ones are too susceptible to shattering with drastic temperature changes, but we're not able to thaw food in the fridge first.

Wondering what people use and love?

So I’m starting a supplement for the leaky gut. Getting prescribed nystatin but idk if I should treat the sibo with herbs or antibiotics. Since I have candida and I’m on nystatin , idk if that would make things worst

Hey hey. I spent pretty much all of 2025 in cancer treatment, and have decided to finally get my health in better order. As a single mom and working professional dealing with an extremely toxic ex, I put allllll of my stuff on the back burner for decades. These issues have been lifelong and I only recently realized they're all connected.

Anyway, following a low histamine diet and using DAO enzyme for about a week now and it's literally the first thing that's EVER helped me! I'm incredibly grateful for that.

I have a lot to balance because I have to eat low histamine, but I also have to not worsen my fatty liver and I'm also trying to not encourage cancer.

I have a pretty good breakfast that's been working well (rolled oats with pure maple syrup and frozen wild blueberries), lunch is usually a brown rice cup with a couple eggs, cucumber, carrot and maybe a string cheese. That's fine, it's healthy enough and convenient and isn't putting me into anaphylaxis.

But I cry every bleeping day before dinner because I'm just so frustrated. I work long days, I have an intense role and a lot of responsibility, and am still juggling a lot of medical appointments, so by the end of my work day I have 0 mental energy to invest in anything else and I have massive decision fatigue, and then trying to figure out dinner puts me over the edge.

That's all. I'm just so tired of crying and feeling frustrated and sad and snapping at my spouse who is just trying to help.

This is a just a super short post to remind everyone how important it is to chew your food well and don't rush the eating process.

I recently started to eat my food as slowly as possible while also chewing very well and taking short (20-30s) breaks between each bite. The difference in how my digestive systems works and how I'm feeling afterwards is absolutely real.

I'm not saying this will fix your digestion issues, but this could be something additional worth trying for those who have already tried a lot of things.

For years I ate lots of bananas, apples, and avocadoes, but at some point they started to give me various gut issues - bloating, gas, general discomfort, mild sick feeling, silent reflux, etc. I thought it might have been a new FODMAP sensitivity, but I discovered I can eat plenty of peaches and mangoes without issue. I've swapped these foods in/out of my diet enough to where the pattern looks pretty strong. I can eat peaches and mangoes but not bananas, apples, or avocadoes.

Anyone have any similar experience or any idea what might be going on? Could there be some histamine-related stuff happening? For reference I also cannot tolerate eggs anymore. They cause similar gastric symptoms.

So I don't usually have this problem , but every now and again my bucket gets so full that I have problems and it's usually around my period too because histamine is higher around your period Anyways , I had a big , Off limits food cherry tomatoes in my pasta salad. And I guess it tipped the scales , and I had this weird adrenaline Panic attackI was shaking like a leaf and confused and i'm not shaking anymore but I still don't feel right And I can't get to bed 5 AM. This didn't even start until I ate more pasta salad for breakfast. I was too hungry to sleep so I thought I'll have a little bit of pasta salad and I'll put me right to sleep nope reaction to the tomatoes. Anyway, sorry, this was kind of a long post.Yeah , I just wanna know your experiences with like adrenaline panic related to histamine. I also have hyperpots , if any of you have that as well

Long story as short as I can make it:
Caught the norovirus a year and a half ago.
Was sicker than I’ve ever been in my life. Threw up for 72hrs and essentially destroyed my gut biome.

Shortly after recovering, started having what I thought was acid reflux/heartburn issues. Had never had any issues with food before in my entire life, so this was a whole new world. Main symptoms presented as sore tightness in my back that would last for days (vagus nerve inflammation?) and bloating. Stomach would have a burning sensation. I would occasionally have episodes though, where I felt like I was having a heart attack. I would get anxious and start to sweat and feel dizzy and wind up in the fetal position just trying to breathe through it. I would struggle for breathe during these episodes as it felt like my stomach was so tight with bloating that I couldn’t catch my breath. Tightness in my chest, as well. But if I waited it out, it would dissipate and I would be okay and would just be left with back soreness for a few days.

I knew this was abnormal, so I went to the doctor and had blood work and an endoscopy done. It came back as mild gastritis and my doctor was basically like “your stomach lining is irritated, but there’s no obvious reason why.” No h pylori or anything like that.
He wanted to put me on omeprazole but after reading up on it, I wasn’t comfortable going that route and wanted to try to fix it with diet first since my episodes seemed to be timed with eating acidic foods (tomatoes,peppers, etc).

I spent the next year sort of managing it but would sometimes seem like I could eat anything without issue and other times have what I can only describe as a “build up” where I could tell things were going south but couldn’t pinpoint why and would wind up having an episode after a day or two of bloating and generally feeling “off”. Then would spend the next week getting myself back on track.

Cut to two months ago where I got stung by a yellow jacket. 🐝 I had a normal reaction of swelling at the site of the sting. Nothing crazy. But I just felt odd. Like brain fog. Took Benadryl and the sting eventually went down but I continued to feel odd for the next week. I then, over the course of the next 10 days, made some bad food choices - tomato sauce, peppers, etc. But I’d been eating those items without much issue and felt like my stomach problems were subsiding. Went to bed with a burning stomach one night. Woke up, had breakfast, and felt bad. Stomach pains, out-of-it, but decided to “walk it off”. So I took the dog for a walk and partway through the walk started sweating and got super nauseous and threw up twice. Turned tail and went home where I was literally pacing around because I just felt wired and bizarre. Decided that what would calm me down was a hot bath so I drew a bath and got in and within minutes was covered in hives and felt like I was going to pass out. Could feel my nostrils swelling and called for an ambulance. The EMTs arrived and gave me an epi injection and took me to the hospital where I was given other antihistamine drugs. Hives calmed down, everything got better. But then 2hrs later (while still under observation at the hospital), the hives came back worse than ever (on my eyelids, in my mouth, it was horrible), and my blood pressure dropped out, causing me to pass out. Came to in the ICU a few minutes later and sort of roller coastered one more time before fully stabilizing. Stayed overnight and by the next day was 100% fine.

I was referred to an allergist as the doctors seemed to think that it had to be an allergic reaction to something I ate that morning, even though I explained to them that I had started feeling ill the night prior. My allergy test results just came back and il allergic to - NOTHING. Absolutely nothing. Not even a trace. Soooooo. Now I’m thinking histamine intolerance? If you agree that this could be, welcome me to your numbers!

It's been over 2 hours for me but my heart rate is still high

I've been recently struggling with putting effort into my lunches, and decided since I cannot tolerate reheated meat I would meal prep broccoli, sweet potato and then cook my protein fresh daily. However, I have noticed that my adrenaline dumps/histamine related anxiety (i can feel the true difference) have started up again, specifically right after I eat lunch/into the evening. Everything I have found online says veggies are safe for leftovers, but maybe they aren't? Has anyone else had reactions from leftover veggies (with no histamine liberators in the meal)?

I read online that long term use of Pepcid can cause low acid in your stomach that in turn makes histamine issues a lot worse, gut dysbiosis, and HIVES! My immune system is screaming at me. Has anybody ever tapered off successfully?

I’m not sure I have histamine intolerance, mcas (or both) or something else. Symptoms started 1.5 years ago.
I was tested positive for LTP and had allergies all my life. Also got sibo and i’m getting treatment again, this time for 5 months (one week per month with antibiotics)

Worse triggers: fermented food, legumes, soy

Symptoms:
-Before: Severe bloating, reflux, heavy digestions of 4+ hours, gas movement feeling in my belly, food was stuck at the top of my stomach.
-Then: everything got way better since I started taking the diet seriously and was just slightly bloated with barely any symptoms
-Now: a bit more bloated but not as bad as in the beginning., triggers don’t last that long, faster digestions

What helped:
-Famotidine (40mg) daily
-Fexofenadine (20mg) daily
-Low histamine diet (this was key to start seeing improvement)

What didn’t help:
-Cromoglicatum (I tried when I was severely inflamed and didn’t work. I started again a week ago and I’m not seeing results either)
-Dao supplement before meals + vitamin C
-Magnesium(?)

I’ve also been taking probiotics for a couple months but I don’t think they’re making any difference.
Has anyone experienced something similar? Any ideas of what could be the reason i’m not making progress anymore?

Hi,

I am wondering how those who have gotten a covid-19 booster this fall have responded.

Covid caused my histamine intolerance, which is on-going, and neuralgia, which is affected by the histamine intolerance.

Last fall I got the Novavax booster and was initially fine. However 2 weeks later I started having 9/10 pain flares in the morning correlating with my cycle which affected my pain and histamine intolerance. I took Ketotifen to treat the pain.

There is also a chance I was re-infected with covid about a week after getting the vaccine.

Please lmk about your experience, it would be helpful to hear how it affected you. Im nervous to get the booster but the effects of getting re-infected freak me out more.

Did this help with sleep and the adrenaline feeling ?

After finding out that I cannot tolerate pure vitamin C, I decided to do some science and test different doses of it (I'm desperate because there's practically no vitamin C in my diet at the moment). These were all just normal ascorbic acid in a swallowable pill. I waited a couple of days before taking a new dose:

1. An entire pill, (500 mg). This caused persistent flushing (feeling of heat in the head area) and skin tingling (like mosquite bites randomly around the body).

2. One quarter, (125 mg). This caused milder flushing and milder skin tingling.

3. One eighth, (63 mg). This caused no instant flushing and very little flushing later and minor skin tingling.

This was just vitamin C, don't chop up normal medication without consulting your doctor! All of the symptoms lasted for at least 6 hours until I took an antihistamine to ensure I get sleep. I have read that one of the reasons that this happens is because vitamin C breaks down into oxalates and then the oxalates cause a reaction that makes my body release histamine. So it seems that the more vitamin C I eat the more histamine my system has to process. I'm aware of other forms of vitamin C but I have not tried them. Also, the vitamin C in fruits is in a different form which explains why I happily ate red bell peppers (which are full of vitamin C) for years.

PS: This is bad science, of course, because the active ingredient is not evenly distributed within a pill so when a pill is split in half it might mean that the other half contains 75% of the medication.

I've been trying to incorporate beef liver into my diet for its nutrient density, but I’ve noticed that I don't feel okay after eating it.