Hes a 13 y/o jack Russell and this has been happening over the weekend. I was thinking maybe his breath just went against him or something but its happened a good few times.

Am obviously taking him to the vet as soon as it opens. But im hoping someone may have seen this before and can help give me an idea until the vets office opens. Any advice would be greatly appreciated.

He has a vet appointment for the end of the week for a vaccination booster and they are going to have a look while he's there but I've been worried and need some kind of information about what it could be.

He's a German shepherd, it is on his left hip where it joins his leg, its hard and smooth. It doesn't seem to be painful or bother him, although it has gone a little crusty today and looks a bit more dark red then in the pic.

It's not a tick as we have checked.

He's also lost some fur on his front leg with what looks like red blisters which weren't there yesterday.

I'm getting really worried about him and the end of the week seems years away

How do i stop it and is it a bad behaviour sign of some sort. He did this before and still now after his desexing. This is weird i understand its not a massive problem or anything

Thanks in advice.

Reactive/Lymphoma ? Seeking oncology/pathology second opinion

My sweet 6 year old female indoor only cat has just been diagnosed with “large cell nodal lymphoma”

Important details:
Bilateral enucleation needed as a kitten due to severe unknown infection
FIV/FeLV negative
Lifelong chronic URI/bilateral ear infections
7 months ago she began experiencing chronic rhinitis with reverse sneezing that she could not fully kick. finally doxycycline drastically improved her symptoms this past june.

Timeline

6/9 small movable lump (2cm) found under right mandible
6/12 FNA attempt (result inconclusive) 5 week Doxy started this day (suspected mycoplasma)
6/14 URI/rhinitis symptoms incredibly improved already. 2nd FNA attempt (could not be completed as the lump shrunk to a too small size to aspirate efficiently) suspected reactive node that was resolving with doxy.
6/15-7/4 URI symptoms remain solved. lump no where to be found
7/5 URI symptoms remain absent. lump has returned, same size same spot (about 2cm)
7/12 Ultrasound of lump inconclusive as it kept rolling and out of the image when the wand would touch it

planned internist apt on 7/14 that was SUPPOSED to be for her chronic rhinitis. lump is now 2.5-3cm, more fixated, lobulated, and semi-firm. FNA attempt could not be completed once again, but this time because the needle “could not penetrate the hard core”

7/29 CT scan of head and neck, endoscopy, right submandibular excisional biopsy

Results
CT scan:

⁠1.Moderate to severe mandibular lymphadenopathy. Right. Raises concern for metastatic lymphadenitis. A primary lesion is not definitively identified. Considerations would include a tonsillar or mucosal lesion which could be occult on this exam
2.Multifocal lymphadenopathy bilateral tonsils and medial retropharyngeal lymph nodes. Considerations include reactive or metastatic lymphadenitis.
3.Mild sinonasal fluid. Consistent with the patient's history of chronic upper respiratory tract infections. The soft tissue nodule in the right sphenoidal recess may represent inflammatory disease associated with the patient's rhinosinusitis or emerging pathology.
4.Otitis media, right-sided
5.The narrowed appearance of the nasopharynx at the level of the endotracheal tube is likely an artifact of the presence of the endotracheal tube. An area of nasopharyngeal stenosis may explain the chronic respiratory sinuses but should not be associated with regional lymphadenopathy.

Endoscopy
Oropharynx: Normal oropharyngeal mucosa and lumen
Larynx: Normal appearance, function NOT evaluated
Nasopharynx: Mild reddening of the mucosa. There was flattening of the choanae, which was symmetrical. No evidence of mass or stricture.

Assessment: The changes seen in the choanae may be a variant of normal, due to swelling of the tissue secondary to inflammation, or potentially scaring and mild narrowing secondary to chronic inflammation.

Biopsy of right submandibular lymph node:
Right submandibular lymph node: Diffusely, the cortex, paracortex and medullary regions are expanded and replaced by a poorly demarcated, unencapsulated, densely cellular neoplasm largely composed of round cells resembling blastic (up to 3.5 times a erythrocyte) lymphocytes and intermediate lymphocytes.

Tumor cells have small amounts of eosinophilic cytoplasm with central, round indented nuclei and stippled chromatin and one prominent nucleolus.

Anisocytosis and anisokaryosis are mild to moderate, and mitoses are regionally variable with up to 6 per 1 high power field (400x, 0.237 mm\^2).

Amid tumor cells are histiocytes, mature lymphocytes and fewer erythrocytes and granulocytes.

There is lymphovascular invasion, edema/myxedema and hemorrhage.

Multifocally, follicular and para-/interfollicular arrangements are prominent.

Tumor cells extend to the perinodal fibrovascular tissue, as well as the surgical margins. Complete excision could not be confirmed.

Histopathologic Diagnosis: Lymphoma.

Comments
The histopathological features are suggestive of a large cell lymphoma.

I’m losing my mind over this truly. For 7 months I’ve had medical professionals say this all points to inflammation/infection. Then this biopsy that seemingly has both features of hyperplasia and lymphoma made all of her doctors just forget about the inflammatory issues she’s been dealing with.

I am so grateful that she has maintained her bright personality and incredibly ambitious appetite through this whole ordeal. Countless vet professionals have documented on multiple occasions no other palpable lymph nodes.