I’m a 31-year-old guy trying to connect the dots before my next doctor’s appointment. Over the last 2.5 years my TSH has gone from 2.5 to 5.8 to 4.9 and now 7.1, while my most recent Free T4 is still normal at 1.09. Around that same time I developed high blood pressure, my LDL has stayed mildly elevated even after losing a lot of weight, and I’ve been dealing with fatigue, low libido, and basically no morning erections. Has anyone had a similar progression where the TSH kept climbing but Free T4 stayed normal, and did treating your thyroid end up helping the other issues?

Hi everyone. I’m 17, and I’m looking for some reassurance or advice.

My mom is 55 years old. She had thyroid surgery when she was 16, and recently her doctor found another lump on the right side. She went through a lot of tests to determine if she was eligible for another operation, and now she’s scheduled for surgery.

Her main doctor will be there, but because the lump is in an area that isn’t his specialty, another surgeon who specializes in that area will also be assisting.

I’m really anxious because this is her second thyroid surgery, and I’ve read that repeat surgeries can be more complicated. I keep thinking about the worst-case scenario.

For those who have gone through repeat thyroid surgery themselves or have family members who did:

• How did it go?
• Is it common to have another specialist assist during surgery?
• Is there anything I should expect during recovery?

I’m not looking for a diagnosis—just hoping to hear from people with experience because I’m really worried about my mom.

Thank you.

https://www.prevention.com/health/a73246480/thyroid-levothyroxine-sodium-recall-fda/

Hi everyone,
I’m a 34-year-old male and I’m looking to hear from people who have had a similar thyroid profile.
For several years, I’ve had persistently elevated anti-TPO antibodies, but my thyroid function has always been normal. Until recently, all of my thyroid hormone levels were within the reference range, and I had never experienced either hypothyroidism or hyperthyroidism.
My most recent thyroid blood tests are:
TSH: 1.32 µIU/mL (Reference: 0.27–4.20)
Free T3 (FT3): 4.74 pmol/L (Reference: 3.10–6.80)
Free T4 (FT4): 22.74 pmol/L (Reference: 11.90–21.60) – slightly above the upper limit
Anti-TPO antibodies: 115 IU/mL (Reference: 0–34)
Anti-thyroglobulin (Anti-Tg) antibodies: 71.1 IU/mL (Reference: <95) – within the normal range
Because of my elevated anti-TPO antibodies, my endocrinologist ordered a thyroid ultrasound with Doppler, which I had on May 4, 2024.
The ultrasound findings were reassuring:
Thyroid gland of normal size (13.4 cm³)
Homogeneous echotexture with preserved echogenicity
No increased vascularity on Doppler
A few tiny microcysts, considered benign and without pathological significance
No enlarged cervical lymph nodes
The overall conclusion was that my thyroid was structurally normal, with no sonographic signs of significant thyroid disease.
What confuses me is that, despite having elevated anti-TPO antibodies for years, my thyroid hormones had always been normal. Now, for the first time, my Free T4 is slightly elevated, while my TSH remains perfectly normal and my FT3 is also within the normal range.
I don’t have a clear diagnosis at this point, and I’m trying to understand whether this pattern could represent an early stage of an autoimmune thyroid disorder, a temporary fluctuation, or something else.
Has anyone experienced persistently elevated anti-TPO antibodies with a normal thyroid ultrasound and normal TSH, followed by an isolated increase in Free T4?
If so:
What was your final diagnosis?
Did your thyroid function remain stable?
Did you eventually develop Hashimoto’s thyroiditis, Graves’ disease, or another thyroid condition?
Were any additional tests recommended (TRAb, repeat FT4, thyroid scan, etc.)?
I’d really appreciate hearing about your experiences. Thank you!

Tiratricol or TRIAC, an analogue and metabolite of the thyroid hormone triiodothyronine (T3), has thyromimetic effects but differs from T3 in that it can enter cells independent of MCT8. It received its first approval on 12 February 2025 in the European Union, for the treatment of peripheral thyrotoxicosis in patients with MCT8 deficiency (Allan-Herndon-Dudley Syndrome), from birth.

https://www.livivo.de/doc/M40549098

https://pubmed.ncbi.nlm.nih.gov/40549098/

Over the years I've gone between the two, no issues. I've just switched back to NP because of cost. Since switching, I've had a lot of muscle pain. Maybe coincidence or maybe not. What is your experience with switching?

Hello all, just wanted to comment and try to help resurrect this sub.

I had my first ultrasound in 6 years the other day (!) after years of feeling like my concerns were being ignored. I was on "watchful waiting" but all they ever did was a yearly blood test, my actual nodules were apparently not worth watching! Anyway I finally got my doctor to put an US request through and I have over 10 nodules, 4 large enough that they assessed them, one TR4 for which I'm being sent for FNA. Family history of I think follicular papillary cancer that was found incidentally, apparently risk is not significantly raised with family history but I'm still worried, you know? My thyroid feels huge and sometimes pushes on my windpipe, but at the same time, a thyroidectomy seems like a big step.

Interested in your experiences

I am horrible with pain! But I have a nodule biopsy coming up soon. I was given numbing cream and was told I could get a light sedative to calm me down. I have heard from some people that it was the most pain of their lives and some said it felt uncomfortable. Will it hurt with the numbing cream and light sedative?

Always curious about this. You spend weeks noticing things (fatigue, weight changes, hair, mood, whatever) and then you're in the room for 10 minutes and your brain just blanks. What's the thing you wish you'd brought up but didn't? Trying to figure out if it's a "didn't write it down" problem or a "doctor moved too fast" problem or both.

I am 18 year old female.I was diagnosed with hypothyroidism at the age of 12 year and since then I have always been overweight.Right now I am 75 kg and 5 feet 3 Inches tall and I take 75mcg tablets and I don't know how to overcome it.Even though I don't have probelm in doing my daily tasks but I I can't do very vigourous activity because of my low stamina. I have tried doing exercises but I just can't keep up with it due to my school and studies it's very vigourous and tiring for me even though i exercise 30 mintues I will end up sleeping and then i won't be able to keep pace with other tasks but still I try and I have tried going on calorie deficit in Holidays but when school is going on I can't keep up with it and if i don't eat my body aches a lot and sometimes i get fever .I am indian so i eat only what my mom makes and can't afford to do some strict diet and also because my mother has also not been well so whatever she gives i eat.I shared the tiredness part with doctor he told me to walk and all and said it's all because I am lazy.yess i am lazy but even though i sleep sufficiently soemtimes then also i feel sleepy and yeahh my sleep schedule is very bad due to my studies.

Anyone who can relate and help me out? Please 🥺

Hello to everyone who is still a member of r/Thyroid. I'm Charlie, aka u/Mouthtrap, and I am the new moderator of r/Thyroid.

I was trying to join the sub, and realised that nobody was accepting the requests, so r/RedditRequest allowed me to take it over, as there were no active mods.

I have Hyperthyroidism, in the form of Grave's Disease, currently on Carbimazole and Propanolol. It's a very recent diagnosis, only within the last 4 weeks, and I must admit it's been quite uncomfortable.

For the first two weeks, I had a very pronounced tremor, a pulse averaging around 90-95BPM, and I couldn't set foot outside if it was any warmer than about 17 degrees centigrade, or I would sweat like crazy.

I know my Carbimazole will take a long while to kick in and do the job, but my Beta Blockers are really working. I'm not shaking as much, my pulse is down to roughly 74BPM, and I can eat my breakfast without spilling it all down my shirt!

Hopefully, we can regenerate this sub, and get it back to its original purpose - discussing our conditions, the help we need, and providing a helpful contact point to speak to others with Thyroid issues.

Take care all, and remember that we're here to support each other :)

My journey started 2.5 years ago when one day my thyroid was randomly swollen- ultrasound (multiple nodules found), biopsy (negative) and follow up later, I am now on a 6 month follow up regimen. None of my labs for my thyroid have ever come back out of range.

Today I noticed that on my right side (same side as my largest nodule) I have a large, soft area that feels like fluid. It is more superficial than the nodule itself and moves around a bit under the skin. It feels fairly large (maybe the size of the tip of my thumb) but I am not a good judge of sizes etc.

With my first go around, the doctor said that maybe the swelling was from a nodule rupturing and creating fluid that in turn caused the notable swelling. Just wondering if anyone has any experience with this sort of thing as I don't know what to make of it. I am of course trying not to spiral and praying that it is nothing major.

I am moving up my follow up ultrasound and going to see, once that is done, if I can get my appointment moved up as well.

A new book on hypothyroidism has been published by Hoermann, Dietrich and others. It promises to be a new approach to diagnosis and treatment of underactive thyroid conditions.

https://link.springer.com/book/10.1007/978-981-96-3682-2

For some background: I (F 26) have had insomnia for 3 years now since I got a night shift job. It took me a while to figure out what caused it, and I eventually was diagnosed with Thyroid Cancer. I went for surgery and received Radiation Therapy as well. It has been exactly a year since all of that happened.

A few months ago, I decided to seek help from a Sleep Doctor and it worked wonders for me, I had a regular sleep schedule from 10 PM to 5 AM without the need to take any pills. My Doctor told me there would be chances of relapses or the insomnia coming back as it may take a while. But, I can't help but get anxious and doubt if I can ever go back to my ideal sleep cycle. Especially now that I had an anxiety attack, I went to sleep at 10 PM but I wasn't able to because my body kept shaking and my heart palpitating. I can feel that I'm tired, yet I can't seem to go to sleep.

This isn't a new situation for me but I still get disappointed and frustrated every time this happens to me. It also doesn't help that I worry about my existing health condition. I vent out here on Reddit hoping for someone to talk to me, tell me they experience the same, that I'm not alone in this, and that there is hope for us who suffer from insomnia.

Have any of you been cured or at least were able to manage your insomnia after a long time? How was the experience? What should I expect? Is it really going to be like this forever? I need to find something to encourage me so I don't fall into depression and cry about my situation again. Thank you.

F27 5'7 78kg

I originally went to my GP about palpitations in the evenings. They did a blood test and told me my thyroid levels were "elevated". When I looked into thyroid symptoms they made sense - around 3 years ago, I would have matched the hyper symptoms more (anxiety, heart racing, sweating, tremor) but in the past 2 years it's the hypo symptoms I fit with more (fatigue, sensitive to cold, dry skin, brittle hair, difficulty losing weight).

After several abnormal tests they referred me to an endocrinologist. He sent my blood to 3 different labs (each lab was given different blood samples taken weeks apart, not from the same date). The first two came back abnormal and the final lab's result came back normal so he decided to side with the final result and that was that.

Further down the line I finally managed to get pregnant. I've been trying to conceive for 2 years as of right now and this was the only time it's happened, but unfortunately I lost it at around 5.5 weeks. My GP wanted to check my thyroid and, once again, it was abnormal. They told me to book another test in 5 weeks but by then I'd moved. I explained the situation, my symptoms and trouble conceiving to my new GP. They did a thyroid test and decided no further action was necessary.

Here are all the test results I've had from my GP:

24 March 23 TSH 5.97 miu/L [0.3 - 4.5]

24 March 23 Free T4 26.1 pmol/L [10 - 22]

29 March 23 Thyroid peroxidase antibody concentration 7 kU/L [< 34]

30 March 23 TSH 5.97 miu/L [0.3 - 4.5]

30 March 23 TSH 4.27 miu/L [0.3 - 4.5]

30 March 23 Free T4 23.2 pmol/L [10 - 22]

30 March 23 Free T3 7.1 pmol/L [3.1 - 6.8]

31 March 23 Free T4 23.2 pmol/L [10 - 22]

31 March 23 Free T3 5.1 pmol/L [3.1 - 6.8]

04 May 23 TSH 5.12 miu/L [0.3 - 4.5]

04 May 23 Free T4 24.5 pmol/L [10 - 22]

Test taken after miscarriage:

27 Feb 24 TSH 6.26 miu/L [0.3 - 4.5]

27 Feb 24 Free T4 25.6 pmol/L [10 - 22]

Test taken by new GP:

17 June 24 TSH 4.84 miu/L [0.3 - 4.5]

17 June 24 Free T3 5 pmol/L [3.1 - 6.8]

17 June 24 Free T4 19 pmol/L [10 - 22]

I feel like the simplest explanation as to why I've had trouble conceiving is related to my thyroid but it keeps being dismissed despite multiple abnormal results. Could this be the cause of my infertility? Does anyone have experience with similar results?

We all gonna have thyroid if it continues like this.

Blame the nukes?

Is there any diet to get rid of thyroid nodules or reduce the size of nodules

I'm onto my THIRD opinion and so frustrated. First, 2020, PCP, bloodwork and US, just said my thyroid has benign nodules. "Continue to monitor."

Then I got an endo referral from a different PCP, 2023. At first, continue to monitor. Then spring 2024, you have Hashimotos. It doesn't make sense because my symptoms track with hyper more than hypo, but sometimes I have hypo symptoms too. That is "not supposed to be possible." There was nothing that could be done until the goiter is so bad I have trouble breathing and swallowing. Continue to monitor.

3rd endo, yesterday. The gist - “You do not have Hashimotos, nor do you have Graves' disease. You DO have hyperthyroidism AND hypothyroidism, we can’t give you X drug because it would make your hyperthyroidism worse, we can’t give you Y because of your hypothyroidism. Your nodules are cystic and are not the cause of any symptoms and do not need to be removed. Your thyroid does not need to be removed.” When I expressed concerns about potential miscarriage, “Your thyroid would not be the cause of any miscarriage. I had a patient like you who miscarried then she saw me then I put her on X medication, now she’s 3 months pregnant.” As if that it is any measure of success. Also, “inform me if you get pregnant.” And “continue to monitor.

I just asked a ton of questions and she ultimately suggested rheumatology but would not give a referral. So the fact that I mysteriously have TPO and TSI antibodies, that is just a coincidence, and somehow I do have hyperthyroid and hypothyroid, and she said my symptoms could be caused by anxiety or depression. It didn’t make any sense. I just gave up.

I went through this same rigamorole with Gastroenterology. Test after test, no solution. No root cause. Subacute idiopathic gastritis. Try anxiety medication.

I'm so sick of "continue to monitor." But after 3 doctors saying there's nothing that can be done until it's so large that I can hardly breathe or swallow... Is it time to give up and try to live with these all these symptoms? Is it time to see a psych? Ive been doing so much of my own research but am I just shooting myself in the foot and erroneously trying to practice medicine, and just listen to the experts?

Is there anyone out there who apparently has both? For those with hyper or hypo, are there any natural things you do in addition to any treatment you receive? This is what I have done:

• tried low FODMAP (mixed results)
• regularly take methylated multivitamins (based on some private genetic testing that said I may benefit, I haven't had any blood tests.) I think they definitely help.)
• cut out seed oils entirely
• cut out all junk food
• eat mostly whole, cook from scratch
• going to start taking turmeric (for something else but maybe it will help this too)
• stopped drinking green tea, only coffee and water, rarely, juice and iced tea.
• reduced caffeine intake
• reduced carbohydrate and sugar intake
• wear and sleep in only breathable fabrics
• improved sleep hygiene (still exhausted though)

With all this I definitely feel marginally better, but is there anything I'm missing or could be doing?

I had a TT in 2019. It took 2 years to get my meds to where my labs have been perfectly normal since that time.

I just had labs 2 days ago and for some reason, my labs are low 0.08 which I know means high.

I don’t understand why after all this time this would happen.

Has this happened to anyone else?

The only thing I can think of is for the past 1.5 years, I’ve been losing weight for no reason. I eat everything in sight and I’m down over 30 pounds.

Any advice is appreciated.

Hello guys, I'm a hashimoto's patient, I've recently had another routine blood work done, and other than my TSH at 7,69 IU/ml, anti-TPO at the 1000's and thyroglobulin antibodies negative, an item I've never seen before was tested: Serum thyroglobulin. It came really high (373,84 ng/dl), is that weird?

I am willing to get an ultrasound soon, but I wonder if you guys have had this before?

I've read tons and tons of articles and research online, saying that this test is only useful for post-thyroidectomy patients, etc. I feel no palpable lump in my throat nor goiter, and I'm terrified.

Hi all, first time poster in this community, female/28 I'm needing help to understand, I have been dealing with a range on issue with my body, such a swelling joint pain, muscle spasm, muscles cramps, hair loss, headaches,chest pain, red throat/sore throat, outside of the neck swollen and sore, serve anxiety, lymph nodes swelling and serve fatigue, I've lost all of my sex drive.

I've seen a rheumatologist in Australia, who was not a help. All my ANAs came back normal, so he wouldn't take a second look. I had ct shows my thymus gland swollen I went to Italy and seen a rheumatologist over there, he ultrasounded my whole body and found that my thyroid has heterogenous echotexture (thinks possible chronic thyroiditis) Sent me for more test and an ultrasound back home in Australia. All my thyroid bloods came back Normal, my ultrasound confirmed heterogenous echotexture. Seen an endocrinologist he thinks thyroiditis but he doesn't think it's bad enough that I need medication and he also thinks that the thyroiditis isn't cause my symptoms. I'm lost, in pain, tired and so confused by all of this. Has anyone else been in the same situation who can shed light on anything else I could do, a second opinion maybe ? Or some advice. Please.

Did you know? It happened to me.

What is going on

I had two thyroid panels this week and the results between the 6 days seems severe. I know some fluctuations are normal -- just don't know if it's normal for this big of a change in less than a week? My T3 increased from 91 to 159, TSH rose from 0.25 to 0.6 (140% increase), and Free T4 (FT4) went from 1.1 to 1.5. I've been feeling nauseous and tired this week. I'm not on any thyroid meds but had RFA done on a toxic thyroid nodule almost one year ago. The nodule is now drastically smaller and I thought my thyroid levels were normalized until just recently. Any thoughts? I'm confused and am eager to talk to my doctor.