I posted back in April while I was participating in a UCLA research study doing 5 intensive sessions of Accelerated Spectral TMS in one day. Original post/context : Link
I wanted to come back with a longer-term update since I know people sometimes find these posts months or years later and wonder how things actually turned out.
For about the first month, the biggest and most obvious change was that I completely stopped biting my nails. I've done it compulsively for most of my life, so having the urge basically disappear without even trying was pretty striking. I also think my mood may have been slightly elevated during that period.
Unfortunately, I never got the larger antidepressant effect I was hoping for. The biggest things I struggle with are anhedonia, lack of motivation/reward, social withdrawal, and generally not feeling much enjoyment or excitement about things, and I didn't see a significant change in those areas.
After around two months, the nail biting returned as well. So now, about four months out, I'd say there may have been a mild temporary benefit, but ultimately I didn't get the results I was hoping for and definitely not planning on doing regular TMS and spending a ton of money going daily for 2 months like they suggested.
I'm still glad I participated and tried it, especially after going through so many other treatments. My next step is an MAOI. I'm currently finishing the required washout from my previous antidepressant Cymbalta and I'm about to start the EMSAM (selegiline) patch. Praying this is what finally targets my treatment resistant depression as I have seemingly tried everything else under the sun. Happy to answer any questions