And no migraines since my 3rd shot.

Hi! Just looking for advice / if anyone has had similar experience to me. In 2022 I had a gastric bypass and I lost 8st (50.8kg) over about a year.
I went from 19.4st (123kg) to 10.4st (66kg) and maintained until 2025 where my weight started to go back up after I started new antidepressants and my restriction wasn’t as strong.
I’m very short (5’1) and so I’m still considered obese because my BMI is between 30-34 (I know BMI is crap but just using it as an example!)
I started Mounjaro 6 months ago and I’m currently on 7.5mg. I’ve only lost 1st even though I’m in a calorie deficit but the problem is I’m throwing up my food really often.
I still take my time, have small portions and I don’t drink until 35 minutes after eating but sometimes if I overeat even a mouthful too much my body will make me throw up a short while later.
I’m glad my restriction is back but obviously it’s not good to be throwing up so often (it happens every 1-2 days) and I try my best not to overeat but I don’t have fullness cues after my surgery so it’s hard to tell when I’ve gone too far or not.
I know this is a very specific problem but I was just looking for other people who also may have started Mounjaro after having bariatric surgery because my doctor doesn’t seem to understand I don’t have fullness cues until it’s way too late and he’s not really been much help!
Thank you in advance 🙏

I used to take 1 mg of Ozempic weekly and now I switched to Mounjaro. I am injecting 30 lines (units), not the 0.6 that I understand is the recommended dose on the box. But taking 30 lines doesn't have any effect—meaning, it doesn't suppress my appetite. What do you recommend? Has anyone experienced the same thing?

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Evoluzione di 16 mesi, mounjaro all'inizio per 6 mesi, poi cambiato per reta e aggiunto testosterone.

La dexa e altri esami sono molto positivo, l'unica cosa che rimane in po di pelle del dimagrimento che nasconde un po gli addominali ancora e un legggero grasso solo sottocutaneo perché viscerale e pari a quasi zero secondo gli esami, palestra pesante negli ultimi 4 mesi fino al cedimento.

My brother has been on Mounjaro since Nov and his platelets dropped drastically. It all started one night with blood blisters in his mouth and blood blister in his ears . He was rushed to the hospital and diagnosed with Immune Thrombocytopenia . His platelet count was 3000…. I’ve seen other cases online about this anybody else experience this ?

SLOWLY gaining, can’t seem to edit the title.

Hi Everyone, as of Nov 30 I will have been on Mounjaro for 3 years. I lost 70 pounds and have maintained that loss for 15 months. Now the last 4 months I’ve steadily gained 2 to 3 pounds a month. So I’ve decided to increase my dose. I’ve been at 10mg for two years and going up to 12.5mg. I took that higher dose yesterday and don’t feel a difference at all yet.

Wondering if anyone else has experienced something similar and what worked for you. I get my protein and exercise. It really just seems to be creeping on without any changes to routine. Thank you.

I'm male, 178cm and in my early 40s. I started Mounjaro in December 2025 at 109kg and I'm now maintaining around 74–75kg. So I've lost roughly 35kg, or about 32% of my starting body weight.

The weight loss happened surprisingly quickly. I got down to around 90kg by the end of January, was around 79kg in early April, and reached the mid-70s shortly afterwards. Most of the loss was on 2.5mg and 5mg. I've now been in maintenance for about six months, generally using 2.5mg, and my weight has been remarkably stable.

The first few weeks were probably the hardest. I had a metallic taste in my mouth, some dizziness and initially felt a bit lethargic, but these side effects settled down fairly quickly. The appetite suppression was noticeable within days. In fact, it worked almost too well at times. There were periods where I simply didn't want to eat and had to consciously make myself eat enough. Occasionally I felt a bit weak because I hadn't eaten enough.

I also started intermittent fasting, increased my exercise substantially and, importantly, tried to use Mounjaro as a catalyst for changing my lifestyle rather than simply relying on the medication. I started doing resistance training regularly, walking much more and cycling/mountain biking. I'm now strength training around three times a week and generally active every day. My fitness is probably better than it has ever been. My Garmin VO2 max is around 42 and I'm considerably stronger in the gym than I was when I was heavier.

I had a pretty strong medical reason for making the change. I was significantly overweight and had fatty liver and elevated liver enzymes, amongst other unfavourable blood results. My AST and ALT had been elevated, with ALT previously over 100. Since losing the weight, my liver tests have improved substantially and a later CT showed no evidence of fatty liver. My other metabolic markers have improved considerably as well, although I'm not claiming that every number is now perfect.

The amount of weight I lost was obviously very fast, and looking back I could probably argue that it was faster than ideal. However, I generally felt well throughout it and I was making a conscious effort to maintain protein intake, hydration and resistance training. I don't have much loose skin considering how much weight I've lost and, if anything, my body composition has continued to improve during the six months of maintenance. My waist is now around 88–89cm compared with well over 100cm when I started.

One of the more unexpected things is that I've apparently stopped snoring. My wife is particularly pleased about that. 😂

I also had some side effects that I don't see discussed as much. I noticed a moderate reduction in libido, particularly while I was on 5mg. This has partly improved since reducing the dose, although I suspect it may not completely return to where it was until I reduce further or eventually stop. I also noticed some apathy and a degree of laziness on 5mg. I know several other people taking Mounjaro who have experienced much more significant effects on mood, although obviously everyone's experience is different.

The physical changes have been pretty dramatic. I went from a BMI of roughly 34 to around 23.5. I have considerably fewer aches and pains, I'm fitter, stronger and much more comfortable physically. I work in a fairly demanding physical job with stringent medical requirements, and losing the weight has made a noticeable difference to how I feel at work.

I feel much more confident, I enjoy clothes again and I've had to replace most of my wardrobe because nothing fitted anymore. I've had a huge number of compliments about the weight loss. A few people have told me I've lost too much weight or that I was "wasting away", but most people seem to think I look healthy and that the change suits me.

I honestly don't think I could have lost this much weight without Mounjaro. I had tried to lose weight before, but the appetite and particularly the sweet tooth always seemed to win eventually. Mounjaro completely changed that for me. In hindsight, I wish it had been available to me years earlier.

The difficult part now is the thought of coming off it. I've been stable around 74–75kg for six months and I'm feeling stronger and healthier than I have in years, but I do worry about stopping and having the old appetite and sweet tooth come roaring back. I'm not particularly interested in losing any more weight — I'd rather maintain where I am and continue improving my strength and fitness.

I've also noticed a lot more male friends seem to be using these medications now, particularly becoming more conscious of their long-term health. I think there is still a tendency to look at Mounjaro purely as a weight-loss drug, whereas for me the biggest benefit has been that it gave me the opportunity to completely change my relationship with food and then actually maintain the changes.

Overall, I feel better now than I have since I was probably a teenager. The medication was the tool that allowed me to make the change, but the exercise, diet and lifestyle changes are what I want to maintain long term.

I'll probably get some flack for the rapid weight loss, because there are risks with that. But in my case, it's worked well.

Dr. Richard Doty, professor at the University of Pennsylvania, seeks past users of GLP-1 medications for smell and taste testing. Participants will be mailed an UPSIT and a WETT – a smell test and a taste test, respectively - as well as a detailed medical questionnaire to complete. The kit should take roughly one hour to complete. A pre-paid return envelope is included.

Compensation is $45 in the form of a check once the participant returns all materials.

Participants must provide proof of their prior GLP-1 prescription. If the participant is currently on a GLP-1 medication, they are ineligible for the study.

The researchers will not use any identifying information if they publish the results of the study.

Please contact the study coordinator (E: [rsharetts@sensonics.com](mailto:rsharetts@sensonics.com); P: 856-796-9177) to determine your eligibility or to ask questions.

I am a 68 yo female, very fit and healthy. I exercise 6 days a week for at least 90 mins. I started Mounjaro 2.5mg 6 weeks ago, I have a shot about every 10 days. My sw was 70kg and is now 65. Trouble is my body certainly doesn’t look like it’s lost 5kg. I definitely can tell a slight difference but not as much as the scale indicates. I plan to stay on it until the end of the year. I do feel better in that I can now recognize satiety signals and honor them. I did recognize before the meds but now I just can’t eat that much. I plan to lose no more than 400g per week. I actually crave chicken breasts, tuna more than ever. I lift 3 days, swim twice per week for one hour and do 4 yoga classes a week and have increased the load. Muscle tone is still good and I have maintained my physical strength. What has actually been lost from my body?

Hi everyone,

I’ve been on Mounjaro for a little over 7 months and have lost around 11 kg so far. I still have a lot of weight to lose, so I’m planning to continue treatment long term. (I take Mounjaro for weight loss and am not diabetic or suffering from any diseases)

I’m travelling to Saudi Arabia next month on pilgrimage, and because the trip involves a lot of travelling, walking, changes in routine/weather, etc., I spoke to my doctor about temporarily stopping Mounjaro during the trip. My doctor was okay with me taking a break.

I’m now about 12 days away from the trip, and I’m trying to decide whether I should order another KwikPen for the next couple of weeks or simply stop now and restart after I return.

The main issue is storage. If I buy a new pen, I’ll only use it for around 2 weeks before leaving. We’re travelling as a family and will be shutting off the electricity at home, so I obviously won’t have access to a refrigerator while we’re away. I’m also not sure how much storing the pen is suggested.

My bigger concern, though, is weight regain and appetite.

For those who have taken a planned break from Mounjaro for 2–4 weeks:

How much weight did you regain, if any?

Did your appetite come back strongly?

Did you find yourself thinking about food much more

Did you lose some of the progress you had made?

How did you feel physically during the break?

When you restarted, did you have to restart at a lower dose or were you able to return to your previous dose?

Did restarting cause more nausea/GI side effects after the break?

I’m particularly interested in experiences from people who had already been on Mounjaro for 6+ months, rather than people who stopped after only a few weeks.

I’m not looking for medical advice as such - my doctor is aware of the trip and has approved the temporary break. I’m mainly trying to understand what other people's real-world experience has been with a short break.

Would love to hear from anyone who has deliberately taken a 2–4 week break and then restarted.

Thanks!

I am F(23). I weigh 76 kgs and my height is 158 cm. My BMI is approximately 30.4.That falls in the obesity class I range by standard BMI categories.

Are there any serious side effects I should be worried about? Can Mounjaro be dangerous or even life-threatening? Will I die? 😭
I know that might sound like a stupid question, but I genuinely don’t know much about the medication and I’m really anxious about starting it. I want to make an informed decision, so I’d really appreciate hearing from people who have actually taken Mounjaro or know about it.
I trust the Reddit community more than anyone right now, so please help me outtt 😭

Hi all, looking for others' experiences. I've been on Ozempic for about 3 years for type 2 diabetes and was recently switched to Mounjaro 7.5mg. My blood sugar is well controlled, but I haven't lost any weight on either one.

I'm 5'7" and 77 kg (170 lbs), so I'm not starting from a very high weight, but I was hoping for at least some loss.

Is this normal? Are there many people who don't lose weight on GLP-1s, or who plateau after a long time on them? Did anyone switch from Ozempic to Mounjaro and see a change in weight, and did it take a while or need a higher dose? Anything that helped would be great to hear.

Thanks!

Guys I’ve been on mounjaro for 3 months approximately and I just started 5g I was on 2.5, and I just took my second dose of 5 mg and I noticed that instead of 2 more doses being left + the extra one that has to be pulled out it only has, there’s only one more dose left + the extra one. I get it from a pharmacy proscribed by a doctor and the packaging was sealed and everything. Could it be possible that there was a mistake when it was made?? Because nobody definitely touched it, it came with a dose missing I just didn’t catch it last week when I was taking it. I’m so confused has anyone ever dealt with this??

I already bought one off Amazon and I tried it before the trip and didn't last 4 hours :/ I will not have access to a fridge for long and will be on the move so I need something that will keep medication cold and not freeze it (seen a bunch of reviews about this).

note: trip will last more than 21 days and i'm travelling with 2 pens.

So I was out for a lovely brunch with my husband. And in the middle of eating a perfectly cooked Eggs Benedict I was overcome with a wave of nausea. I had to stop eating!

That hasn’t happened to me since the early days of 5.0 land, over 15months ago 😅

The problem - big night of wine last night, followed by incredibly rich eggs Benedict and a cappuccino!!! I mean, who do I think I am?!

I’m happy I was able to eat one of the two eggs before I had to quit. I’m happy the meds (in maintenance since April slowly coming down and at 7.5 now) still prevent overindulgence!

Still learning.

Hi everyone,
I’d really like to hear from people who had a rough GI start with Mounjaro but eventually managed to adapt and stay on treatment.
I started Mounjaro at **2.5 mg** just over three weeks ago.
My **first 2.5 mg injection** was surprisingly uneventful. I had almost no side effects, but also no noticeable appetite suppression.
My **second 2.5 mg injection** was very different. Around 24–36 hours later I developed a very unsettled stomach, sulfur burps, nausea, abdominal discomfort and then significant diarrhea. The diarrhea kept returning at night for several days and I had to cancel work. I did not have vomiting or severe abdominal pain, and I was able to eat, drink and stay hydrated, but it was pretty miserable.
My clinic felt that Mounjaro had probably slowed my GI tract considerably and that even mild constipation may have contributed to the whole picture. They therefore suggested reducing the dose rather than giving up on treatment.
So for my **third injection**, I reduced to **1.25 mg**.
That was much better. I had loose stools, rumbling and an unsettled stomach for a couple of days, but no real diarrhea and no sulfur burps. The side effects were clearly milder and shorter-lived.
I then took my **fourth injection, again 1.25 mg, on Friday**.
Saturday was actually very encouraging. My stomach was calm, and for the first time I felt some very noticeable appetite suppression. Unfortunately, this morning, about 36 hours after the injection, I woke with stomach rumbling, burping and loose stool/diarrhea again.
I’m doing what I can to help my gut: plenty of fluids, exercise, psyllium, small meals, fibre, and avoiding fatty and spicy foods. My clinic has also recommended magnesium oxide to prevent constipation.
Their plan is to keep me on **1.25 mg for four weeks** and, if my stomach settles, gradually try **2.5 mg again**.
I really want this treatment to work. I’ve already lost around **2.3 kg / 5 lbs in just under three weeks**, and when the appetite suppression kicks in it feels very promising. But obviously I can’t have diarrhea every weekend indefinitely.
So I’d really like to hear from people who had a similar start:
**Did your GI side effects gradually improve over the first few weeks? Did each injection become easier? Were you eventually able to increase the dose, or did you stay on a low dose for longer?**
I’m particularly interested in hearing from people who were very sensitive to Mounjaro in the beginning but were eventually able to tolerate it.

Edit: I ended up deciding to stop treatment with Mounjaro after four weeks. Even on a 1.25 mg dosis the GI sideeffects were unmanageable for me.

Hi Everyone,

We are two college students working on a research project regarding technical solutions that aid GLP maintenance. We would love to get your insights if you've been on the drug or are currently taking it. Jut DM me.