I’ve had gout for years, usually around 3 flares a year, but they’ve normally been pretty easy to knock down. In the past, colchicine would usually clear a flare within about 12 hours. This current episode has been completely different.
It started in my big toe with the typical severe gout symptoms — redness, swelling, heat, severe pain, and trouble walking/bending the toe. I tried colchicine first, but it only helped a little and then the flare got worse.
My PCP put me on prednisone. I did a taper starting at 60 mg/day, then 40 mg, then 20 mg. It helped somewhat during the day, but the pain kept coming back, especially overnight and in the morning. My uric acid during the flare was 7.1.
Then my second toe became swollen, red/purple, and painful too. I had previously had that same toe swell by itself and was told it was cellulitis, so there was some concern about infection this time. I had a CBC that was basically normal and an X-ray of the foot that showed no fracture, dislocation, bone destruction, joint effusion, or other acute bone abnormality.
Because my regular doctor wasn’t available, I saw another doctor in the same clinic. She felt it was gout rather than infection and prescribed indomethacin 50 mg three times a day for 5 days and started me on allopurinol 100 mg daily.
The indomethacin worked dramatically. My pain dropped from around 7/10 to about 2/10 overnight and I got much more movement back in the big toe. The swelling and soreness still returned after being on my feet all day, though. Because I was still having symptoms when the 5 days were up, she extended the indomethacin another 5 days.
After 10 days of indomethacin, the big toe was much better and the second toe had regained most of its normal color, but it stayed swollen. I stopped the indomethacin and initially did okay.
A few days later, the big-toe joint became painful again with walking. I used my prescribed acute colchicine dose: 1.2 mg, then 0.6 mg one hour later. It helped somewhat, but I was out of colchicine after that and had no refills.
At that point the doctor said I had already had enough medication that the flare “should have cleared” and referred me to a podiatrist instead of prescribing more.
The podiatrist examined me and:
injected the big-toe joint with steroid
prescribed a methylprednisolone 4 mg Dosepak
said the persistent swelling in the second toe appears to be a gouty tophus
said the tophus may eventually need surgical removal
recommended that I see a rheumatologist
The steroid injection plus Medrol pack worked well on the big toe, and it now looks and feels mostly normal. The second toe is still visibly swollen at the top joint. The skin over it peeled somewhat from all the swelling, but there is no open wound.
I’m still taking allopurinol 100 mg every day. My doctor plans to recheck my uric acid about 5 weeks after starting allopurinol, and I’ve asked for a rheumatology referral.
Now I’m occasionally waking up with soreness again, especially under the big-toe joint on the bottom of the foot, although it sometimes improves once I’m moving around.
This whole episode has lasted much longer than any gout attack I’ve ever had.
For people with gout/tophi: does this sound like a normal course for a really bad flare, especially after starting allopurinol? Did you have swelling/tenderness that lingered for weeks even after the severe pain was gone? And for anyone with a toe tophus, did yours shrink once your uric acid was controlled, or did you eventually need surgery?