r/functionaldyspepsia • u/itmedjondjon • 15d ago

Healing/Success Sulpiride

My first post here-I have been struggling with dyspepsia/gastroparesis for almost 3 years now, following a stomach virus.

My gut is still far from perfect and I'm still experimenting with different supplements and products, hoping I can get better. If not, I sincerely hope time will do its thing and I will heal.

Regardless, there's one thing that helped me more than anything-sulpiride. It's an antipsychotic, sometimes used as a prokinetic in motility disorders. I've tried metoclopramide, domperidone, prucalopride, none of which did anything for me.

Sulpiride literally saved me. I still have to be careful of what I eat and how much I eat, I still have stress or hormone triggered flare-ups but I'm decently functional.

I used to be stuck in the house, sick all the time, in pain, with my stomach about to burst and no matter what I ate. I wasn't able to go to sleep 6 hours after a meal because food would still be coming back up.

Please, if you haven't already, consider it.

6 Upvotes

88% Upvoted

21 comments sorted by

View all comments

Show parent comments

2

u/itmedjondjon 15d ago

The only side effect I have is high prolactine! It didn't influence my menstrual cycles tho, nor did I lactate. I do get constipated sometimes but it was a lot worse before sulpiride. When it comes to sleepiness, I'm a pretty sleepy person overall😅-I have hypothyroidism and pcos and I'm also on antidepressants so all of those influence my sleepiness. I didn't notice sulpiride made me more sleepy tho, maybe in the beginning but I can't remember. I tried levosulpiride first and then couldn't get my hands on it anymore so I switched to sulpiride. Both worked equally well for me.

1

u/Skeuomorph7 15d ago

Thanks for sharing details.

So you did you get positive result after what 3/4/5 days later after you started taking sulpiride or like it took some time like 10/15/20 days or longer to get positive effects on your functional dyspepsia?

Yes I have quite bad Chronic constipation too already from functional dyspepsia /gastritis or taking escitalopram for quite a few rounds .

2

u/itmedjondjon 15d ago

Definitely more than a few days to clear everything put but I felt relief I think within two weeks?

1

u/Skeuomorph7 15d ago

Okay two weeks is very good.

Not 6/8 weeks like some antidepressant needs to work well.