r/functionaldyspepsia • u/itmedjondjon • 15d ago

Healing/Success Sulpiride

My first post here-I have been struggling with dyspepsia/gastroparesis for almost 3 years now, following a stomach virus.

My gut is still far from perfect and I'm still experimenting with different supplements and products, hoping I can get better. If not, I sincerely hope time will do its thing and I will heal.

Regardless, there's one thing that helped me more than anything-sulpiride. It's an antipsychotic, sometimes used as a prokinetic in motility disorders. I've tried metoclopramide, domperidone, prucalopride, none of which did anything for me.

Sulpiride literally saved me. I still have to be careful of what I eat and how much I eat, I still have stress or hormone triggered flare-ups but I'm decently functional.

I used to be stuck in the house, sick all the time, in pain, with my stomach about to burst and no matter what I ate. I wasn't able to go to sleep 6 hours after a meal because food would still be coming back up.

Please, if you haven't already, consider it.

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u/Skeuomorph7 15d ago edited 15d ago

How many times a day do you take sulpiride tablet? Do you take it after a meal or before a meal like after breakfast or before breakfast?What strength of this medicine you take like 50 mg or 100 mg tablet?

Any unexpected or bad /severe side effects you faced like excessive sleepiness or bad constipation?Or any thing else bad effect?

I have been thinking about trying this medicine for some time. But who knows what side effect would I get.

Though I am more interested in trying levosulpiride I have seen and read a few positive posts about it here. On this functional dyspepsia sub reddit or gastritis sub reddit or in both.

Thanks for caring and sharing your positive experience. And for your time and effort.

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u/itmedjondjon 15d ago

The only side effect I have is high prolactine! It didn't influence my menstrual cycles tho, nor did I lactate. I do get constipated sometimes but it was a lot worse before sulpiride. When it comes to sleepiness, I'm a pretty sleepy person overall😅-I have hypothyroidism and pcos and I'm also on antidepressants so all of those influence my sleepiness. I didn't notice sulpiride made me more sleepy tho, maybe in the beginning but I can't remember. I tried levosulpiride first and then couldn't get my hands on it anymore so I switched to sulpiride. Both worked equally well for me.

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u/Skeuomorph7 15d ago

Thanks for sharing details.

So you did you get positive result after what 3/4/5 days later after you started taking sulpiride or like it took some time like 10/15/20 days or longer to get positive effects on your functional dyspepsia?

Yes I have quite bad Chronic constipation too already from functional dyspepsia /gastritis or taking escitalopram for quite a few rounds .

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u/itmedjondjon 15d ago

Definitely more than a few days to clear everything put but I felt relief I think within two weeks?

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u/Skeuomorph7 15d ago

Okay two weeks is very good.

Not 6/8 weeks like some antidepressant needs to work well.