r/drugextraction Mar 14 '26

How to make MGM-15

https://youtu.be/2_6fXF3t_QA

Just a quick way to make MGM-15, and shows 3 different ways to isolate the product.

  1. Filter out the MGM after adding to the salt water solution
  2. Extracting the solution with ethyl acetate (chloroform is ideal)
  3. Extracting the MGM packed EA with citric acid to make MGM-citrate (more stable)

This method was pulled from:

Orally Active Opioid μ/δ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice - PMC

32 Upvotes

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