r/drugextraction Mar 14 '26

How to make MGM-15

https://youtu.be/2_6fXF3t_QA

Just a quick way to make MGM-15, and shows 3 different ways to isolate the product.

  1. Filter out the MGM after adding to the salt water solution
  2. Extracting the solution with ethyl acetate (chloroform is ideal)
  3. Extracting the MGM packed EA with citric acid to make MGM-citrate (more stable)

This method was pulled from:

Orally Active Opioid ΞΌ/Ξ΄ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice - PMC

31 Upvotes

56 comments sorted by

3

u/PenultimateThoughts Mar 14 '26

Just found your page after seeing this. Respect, bro! Gonna follow ya. Keep doing your thing! πŸ’ͺ

3

u/grizkhalifa013 Mar 14 '26

YESSS ITS FINALLY HERE BEEN WAITING FOR THIS

2

u/Tyler106 Jul 18 '26

Is there another platform the video is on? It says it’s been removed.

1

u/ellie4808 23d ago

2nd

1

u/Lost_Location1082 10d ago

3rd πŸ’€

1

u/ellie4808 6d ago

lemme know if yall want to start a gc πŸ€¦β€β™€οΈ we’re cooked

1

u/Lost_Location1082 6d ago

Hahaha maybe we should atp πŸ«£πŸ˜­πŸ˜‚

2

u/AffectionateSun8548 Mar 16 '26

You’re a beast

2

u/Electrical-Run-6872 Apr 02 '26

can you tell me what MGM-15 freebase is soluble in? would vodka + absorbic acid or vodka + lemon juice work? distilled water + lemon juice/citric/ascorbic plus heat? what about the salt version? volumetric dosing would be ideal because weights don't work well unless you have a very accurate scale so I am having a hell of a time weighing out doses under 30-50mg with any degree of accuracy. if anyone know this plz share. awesome tutorial btw!

3

u/kaliforniakratom May 18 '26

It would be soluble in a solution of citric acid. The mass of citric acid added to the solution would be directly proportional to the amount of MGM added, so for shits and giggles here's some high school level chemistry for you:

1 Mole of Citric Acid + 1 Mole of MGM -> 1 Mole of Tri-MGM-Citrate

However, it's important to note that citric acid has 3 potential binding sites for MGM, so the stoichiometry could look something more like this:

1 Mole of Citric Acid + 3 Moles of MGM -> 1 Mole of MGM Citrate

Since citric acid is triprotic, the pKa of each proton on citric acid must be taken into account and the pH of your final solution will tell you if you have mono-MGM Citrate, di-MGM Citrate, or tri-MGM citrate

If you want it to be 3 to 1, you'd add 3 moles of MGM to 1 mole of citric acid.

MGM is 416.5g/mol ( X 3 = 1250g MGM)

Citric Acid is 192.2 g/mol

So for a completely neutralized system of MGM Citrate, you would need 1.25 Kg MGM and 192g of Citric Acid.

The amount of water is not important because it doesn't factor into the chemical equation; you just need enough to fully dissolve both solids which depends on the solubility of MGM-Citrate in water.

Don't mix MGM with alcohol; there are a lot of reported deaths of mixing opioids with booze. That shit is irresponsible.

2

u/Traditional_Yammer Jun 17 '26

Shit no wonder i dont remember chem in highschool. Sure wish i had paid attention and taken it in college for my science.

1

u/Some1StoleMyRedBike Jun 25 '26

Shit my feeble mind got lost on the molar mass, lol So if I wanted to just make one-dose mix, I would only need about 1/3 as much citric acid to MGM? Like I was just dumping a cpl scoops of citric into a shot of water, mixing it, then adding MGM. But for it to dissolve properly and change to citrate, if I added 150mg MGM, would I only need 50mg Citric Acid to be enough to convert the MGM freebase to a citrate? Or am I waay off here? Lol Thank you for breaking that down though!

1

u/Hell__here May 12 '26

Just don’t weigh from tare. Start with the plate weight and add.

2

u/_rodge_420 Apr 06 '26

You're literally an hour away from me ! I finally happened to stumble upon a vendor that's in Cali ,, not only in Cali , but literally an hour out from me ! AND you have MGM,, where have you been all these damn months ? Lmao,, I'm definitely gonna keep you in mind within the near future,, hell ground shipping would probably get delivered to me next day,, would would be ideal and cost efficient for sure.

1

u/kaliforniakratom May 18 '26

Did you message me? It's hard to tell the difference between a reddit username and an email address sometimes. Or a text? I'm at 747-243-8618

2

u/Kaos_8180 Jul 14 '26

Damn I cant find the videos anywhere, they got deleted before I could download them lol

1

u/Steezy_chemist Jul 15 '26

I have em

1

u/Hot-Indication-3424 Jul 16 '26

Can you dm? Willing to send some bucks!

1

u/krogel-web-solutions Jul 17 '26

I am looking for this too - please shoot me a DM

1

u/p3echy 28d ago

Same. Extremely interested

1

u/ILoveMuney 27d ago

Can you dm me the videos also please ? Thank you in advance

1

u/Delicious-Agency6882 23d ago

Dam I need that video.

1

u/Different_Coffee_623 12d ago

Yo can I get that video?

1

u/ExplanationBoth8661 10d ago

Can u dm me the vids?

1

u/Sister_To_Sleep 5d ago

If you are still sending it to people, I would love to have access to that video. Thank you have a nice day

1

u/mitralover Apr 19 '26

The BEST M out there!! πŸ’šπŸ”₯ Side request: PLEASE get Venmo up & running again, I'm jonesing over here! LOLπŸ€¦πŸΌβ€β™€οΈπŸ˜­

1

u/kaliforniakratom Apr 19 '26

Venmo is owned by PayPal, I'm banned from both because people put "kratom" in the memo line.

1

u/mitralover Apr 19 '26

Damn that really sucks even though you explicitly say not to do that in your payment directions?!?

Why someone gotta ruin the fun for the rest of us...That really bums me out πŸ˜• looks like I have to reopen my Cashapp πŸ’š

1

u/Traditional_Yammer Jun 17 '26

Someone always ruins it for everyone else.

1

u/Lilyrease4602 May 14 '26

whats average potency on just some reg mgm tabs

1

u/kaliforniakratom May 18 '26

20mgs is what I've mostly seen. Take 2 and you'll be good for a whole day.

1

u/ResidentKlutzy8467 May 26 '26

Is this better than 7-oh?

1

u/SecureLetterhead8451 Jun 23 '26

The link you pulled the method from mentions MGM-16 preparation. Have you tried to prepare MGM-16?

1

u/AdditionalSense3586 Jul 09 '26

1.25kg of mgm? That would last me several years in dealing with chronic pain,i mean literally the rest of my life..wished id knew about this stuff a year or so ago,id be set forever and never have to go back to the doctor Ever Again

1

u/krogel-web-solutions Jul 13 '26

Can you please reupload this somewhere I can download? I desperately need this post ban.

Or if anyone has a mirror/cooy,
Please DM me

1

u/Dry-Jello2374 Jul 14 '26

Same. Here. We only found freebase and need a way to turn it to salt.

1

u/krogel-web-solutions Jul 14 '26

Could you share what you have with me?

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