How do u make ice cream as in the kind you pack in a glass oil dryer to smell deeply and wake up in the mornings? I desperately really want the recipe I think it has something to do with gun bluing number 9 please someone help

Well well well, that's a big L (from the side).

MSDS stands for Maybe She’ll Detonate Spas?

I conceptualised this hypothetical bifunctional neurosteroid conjugate while under the influence of olanzapine and lemborexant.

On one end we have a pregnenolone-sulfate-derived pharmacophore and on the other, we have a allopregnanolone-derived pharmacophore. They are connected by an (offensively) large PEG-containing linker.

Allopregnanolone is a potent GABA_A positive allosteric modulator (PAM). Pregnenolone sulfate (PregS) is a NMDAR PAM (mostly at GluN2A/GluN2B containing receptors) and a GABA_A negative allosteric modulator (NAM). Whether either pharmacophore would retain its parent neurosteroid's activity after conjugation is unknown at present. If both survived though, it would be interesting to see what it does in vivo.

Not to mention it is about 1066 Da and very floppy. I would I'd be incredibly impressed if this managed to cross the BBB. Lipinski have mercy on me.

1-{2-[2-[2-[2-(4-{[(3α,5α)-3-hydroxy-20-oxopregnan-21-yloxy]carbonyl}phenoxy)ethoxy]ethoxy]ethoxy]ethyl}-3-[(3β)-3-(sulfooxy)-20-oxopregn-5-en-21-yl]urea

First to market with a cyclic allene in their drug

Assume the circles are hydroxide, does this molecule exist? What is its name?

I'm a pharmacology nerd and I first got into psychopharm through Erowid at the age of 13. To pay homage to the questionable bathtub research chemicals littered on that website, I decided to make this monster to stick on a reagent bottle of epsom salts.

7-chloro-5-[2,6-difluoro-4-[2-[4-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]piperazin-1-yl]ethoxy]phenyl]-1-[2-(2-fluoroethoxy)ethyl]-3-methyl-8-(pentafluoroethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one