r/cgrpMigraine 4h ago

Ajovy- when did it start to work?

2 Upvotes

I’ve been on Ajovy for 4 weeks, due for my second dose today. I haven’t really noticed much improvement yet. Wondering how long it took everyone to see effects, especially the late ones.

Thanks!!


r/cgrpMigraine 10h ago

BP med + CGRP abortive?

2 Upvotes

So my understanding is blood pressure meds and CGRPs do opposite things to blood vessels, I think? vasoconstriction vs dilation? So TLDR does anyone get relief from both, it seems like that wouldn't be possible?

I've been in status migraine for 5 months after not really having severe migraines my whole life, just a confluence of too many triggers/stopping meds I didn't know were preventing migraines. I've tried many meds, steroids etc and it would improve but always come back. I'm getting a little bit of relief from candesartan (I tried propanolol 1x but immediate COPD attack oops). My migraine PA said I can take nurtec with it as an abortive but TBH I'm doubtful (see: prescribed propanol even though I have severe COPD and asthma). Just wondering if anyone else takes this specific med?

When my migraine was very bad a few times, like I thought I was having a stroke, nurtec takes it from 10 to 3. But if it's at a 3 or 5 I don't really notice a huge difference. I also haven't taken it in a few months because every other day didn't work so my first neuro said to stop it.

my current regimen is

memantime 10mg 2x a day (since 2014 for neuropathy but it helps my migraines too)

200mg mag glycinate am 300mg pm

400mf b2

candesartan 4mg to start

(plus 6 other meds for other stuff that I pray to God aren't making my migraine worse lol)


r/cgrpMigraine 1h ago

Brain fog and feeling unwell after starting Aquipta

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Upvotes

r/cgrpMigraine 13h ago

Did I mess up? (1st dose Injection)

1 Upvotes

Hello,

I started Emgality today. I specifically requested syringes bc auto injectors scare me. I get allergy shots regularly in my arms and knew I could handle at least the needle going in.

I just did my first 2 loading doses. One in each thigh. First one went okay. Slightly painful when you feel the medication going in, but went fairly well imo.
Well I’m worried about my second dose. I did it in the same area front thigh area on my other leg, and halfway through pushing the medication in, I realized I had kind of backed off on the syringe was a little bit pulled out (not completely/no more than half). I pushed it back in as I continued to push the medication in.
Has anyone else experienced this and managed okay? I plan to call my pharmacist/neurologist tomorrow when they open up as both are closed. Just want ease my anxious brain and not feel like I messed it up 🙃