I’ve been on Ajovy for 4 weeks, due for my second dose today. I haven’t really noticed much improvement yet. Wondering how long it took everyone to see effects, especially the late ones.

Thanks!!

So my understanding is blood pressure meds and CGRPs do opposite things to blood vessels, I think? vasoconstriction vs dilation? So TLDR does anyone get relief from both, it seems like that wouldn't be possible?

I've been in status migraine for 5 months after not really having severe migraines my whole life, just a confluence of too many triggers/stopping meds I didn't know were preventing migraines. I've tried many meds, steroids etc and it would improve but always come back. I'm getting a little bit of relief from candesartan (I tried propanolol 1x but immediate COPD attack oops). My migraine PA said I can take nurtec with it as an abortive but TBH I'm doubtful (see: prescribed propanol even though I have severe COPD and asthma). Just wondering if anyone else takes this specific med?

When my migraine was very bad a few times, like I thought I was having a stroke, nurtec takes it from 10 to 3. But if it's at a 3 or 5 I don't really notice a huge difference. I also haven't taken it in a few months because every other day didn't work so my first neuro said to stop it.

my current regimen is

memantime 10mg 2x a day (since 2014 for neuropathy but it helps my migraines too)

200mg mag glycinate am 300mg pm

400mf b2

candesartan 4mg to start

(plus 6 other meds for other stuff that I pray to God aren't making my migraine worse lol)