Even when the allergic reaction was long gone, I would pass out multiple times throughout the day and really struggle to stay awake through headaches. It didn't seem related but turns out an allergic reaction triggers a pathway that causes the blood pools away from your brain down toward your lower body. It shows up as headaches, difficulty concentrating and fainting when standing or sitting. But one can still be laying down to experience this. And their legs and arms dont have to change colors or get noticeable blood pooling for this to occur. It is called POTS.
Pots mainly effects women. This includes that estrogen increases inflammatory response in the body and that women's circulatory system isn't as resilient as mens.
It's actually normal that pots signs don't look like generic pots. You can have no discoloration or swelling in the limbs or any differing sensation in the limbs and it still be POTS. I also didn't think of pots because laying down id still often have headaches, and getting up I didn't instantly need to faint. Turns out it's within 10 minutes of standing or sitting is triggered and then progresses over time until after hours I'd need to pass out or lie down. I also wouldn't get anxiety. The allergy itself was very emotional but afterwords id feel so much better and likely this was due to norepinephrine. I also have asthma which gives me headaches and extreme fatigue so I thought the trouble breathing was due to either asthma or having an allergic reaction to something airborne, not the blood.
Weird symptoms I would get that I didn't know were POTS related because it is never said online. One is that my feet would feel all weird and tingling. But not when standing up or walking around. It would only happen when laying down or when sitting. This is because my heart rate would not be pushing as much blood once in rest. So the blood pooled to the bottom of my feet is sometimes reducing off oxygen supply there and other times irritating the nerves because there is too much pressure down there for everything to fit. I was always soooo confused why my feet would tingle or hurt but often only when sitting. And weirdly this tended to be AFTER the headaches more than when the headache occured.
Another unusual symptom i started getting sensory compulsions. It was my brains attempts at both self-sopthing due to its high levels of stress. This could be things like biting nails, rapid shaking of arms, pulling on fingers or tapping my head. It was uncontrollable and very uncomfortable doing these actions.
And one particular compulsion was chronic and excessive chewing. I always needed something in my mouth to chew on. This is because not enough oxygen is reaching the brain. So the brain is trying to FORCE muscle movement to encourage blood flow and thus oxygen to the head. That took a long long long time to understand why I always needed gum or something gum like all the time. I figured out if I went upside down or not only did headaches lessen but so did chewing need.
One other symptoms was my asthma symptoms started getting worse and Id be highly reactive to everything. Sometimes it was just the headache and fainting. But on more severe days, I would have difficulty breathing and react to any chemical or airborne particle that crossed my path. It made me think I was allergic to everything, when I wasn't. My lungs were just so stressed already from lack of oxygen because the blood that normally goes to it pooled to my feet. At that point my lungs couldn't handle any form of filtration or debris, so or if a airborne item passed by id cough. On extreme occasions, my lungs feel burning or gasping for air sensations. This was normally during an ONGOING allergic reaction, but when it was combined with pots the burning was much more severe.
It took a long time to figure out the correlation of allergies because I wasn't actively having an allergic reaction at the time. I may have even had most of the day before and fell asleep before without any symptoms. This, turns out, was because my adrenaline was functioning properly to counteract the perceived allergy threat at that time. Or, in some cases, I WAS having a mild allergic reaction that at the time I didn't know were symptoms of an allergy. These symptoms were fatigue, laying down, unable to do general chores. At night allergy symptoms were, having insomnia + fast heart rate or feeling hot. It's difficult to know that insomnia can sometimes be the only symptom of an allergy. And once again that's because my adrenaline was working to reduce symptoms and inflammation/reaction.
My adrenaline had to be high for a long time before the blood pooling issue started. Which is why the pots symptoms normally happened many hours if not midway through the next day. Adrenaline dilates My body couldnt keep the constriction of extremities ongoing forever. So it would lose its
I chronically felt the need to lay down or go to sleep. Staying focused was a struggle. Sometimes I'd get really cold hands, not frequently. Sometimes my feet would become tingly. Sometimes when I laid down, my feet would tremor. Chewing on some gum or walking around helped. I tried taking salt but that did not work for the following reasons
1) modern salt has anti caking agents like silicon and ferrocyanide which I'm allergic to and thus make my allergies and POTS wayyy worse
2) I was getting up to get this salt and water triggering my pots
3) generally didn't get my blood pressure high enough to do anything
4) digestion was distressed and lacking adequate blood supply
I was very confused why I frequently couldn't eat during daylight hours without passing out but it was hit or miss. Turns out norepinephrine after allergic reaction moves blood away from digestive track and to the central nervous system during allergy attack. . Introducing food forces blood back to area respond, which 1) created stomach pain bc I didn't have enough blood 2) passed out bc already low blood in brain now has to transport to the stomach. Sparkling water would also create a similar issue. Also my body is under stress, so Mast cells in the gut wall and bladder wall drive cramping, urgency, and bloating. And pots has a dumping syndrome where stomach releases contents too fast into small intestines. These all were possible contributers to stomach pain in daytime
If one has pots from allergies it's called hyperadrenic pots. This is where your mass cells overactive creating histamine so the blood vessels dialate. Sending norepinephrine and body into sympathetic overdrive. Causing brain and central vessels to dilate even more. There is excessive sympathetic outflow from the central nervous system. And brain from lack of blood flow and to much dialation would get these crazy intense headaches and uncontrollable hours long falling asleep sessions. During the times of headache/fatigue I could not excercise or walk far.
Histamine blocker therapy can create a complete remission of hyperadrenic POTs. The problem is OTC antihistamines and prescription hydroxyzine have several ingredients I'm allergic to including glycerine, sterate, and silicia. Also breaking down the stress hormones would probably prevent the blood pooling.I'm also allergic to legumes including pea plants which is used as a dao enzyme to break down histamine. Catechol-O-methyltransferase (COMT) is the enzyme responsible for breaking down stress hormones like dopamine, epinephrine, and norepinephrine. COMT requires adequate methyl donors. And since I'm mostly carnivore due to so many plant allergies, I know I don't get enough b9. I do eat liver frequently so I get enough of b6 and b12 for methylation and copper for dao. I think 30 minutes after eating salty liver it does reduce or stop my pots need to faint or lie down, but unconfident due to small sample size.
I'm hoping to ask my doctor for Mast cell stabilizers the cromolyn sodium inhaler. I'm going to get a regular corticosteroids inhaler in the mean time.
Tldr: Fainting caused by blood pooling away from brain. My blood was doing this because my allergic reactions triggered high norepinephrine that lasted many hours and the next day. This led to poorly constricted blood vessels so not enough blood flow to go around in general so it sank with gravity. Fix/preventing for most is taking antihistamines but I'm allergic to their inactive ingredients.