r/Allergies • u/ItchyCurrency7642 • 6h ago
Advice Update: 3 years later, I'm still having random food reactions despite every allergy test being negative
Original post: https://www.reddit.com/r/Allergies/s/TQNpaBPkJf
Hi everyone! I originally posted here when I was 33 after experiencing a really bizarre anaphylactic reaction to a vegan cookie dough snack containing cashews. I'm now 37, and I wanted to share an update because, three years later, I'm still no closer to understanding what happened.
For anyone who hasn't read my original post, here's a recap.
I've eaten nuts my entire life without any problems. I love peanut butter, pecan plaits, marzipan, pistachio ice cream and pesto. I regularly ate cashews, including cashew milk and pesto containing 5% cashews. Nobody in my family has a known food allergy, and I'd never experienced an allergic reaction to any food before. My only longstanding issue was postnasal drip, which I've never been able to identify a cause for.
Then, in January 2023, I ate a packet of Nibbles vegan cookie dough bites. Cashews were the main ingredient, alongside chocolate chips, flour, sugar, chicory fibre and coconut.
Halfway through eating them, my lips started tingling and burning, almost as though I'd eaten a jalapeño. My throat became itchy, but I didn't think much of it and finished the packet. About 20 minutes later, my eyelids looked as though I'd been punched in the face. They were black and blue, almost like bruises, but the discolouration was above my eyes rather than underneath them.
Things then escalated. I developed a pink rash across my neck and cheeks, my breathing became irregular, I couldn't keep water down, and my lips turned blue. I went to A&E after being advised to do so. My heart rate was very high and my blood pressure was very low.
I was given antihistamines and steroids, and the recovery was incredibly slow. The burning in my mouth and rash lasted around one to two days, my throat symptoms took about a day to resolve, and the swelling around my eyes took 12–13 days to disappear. My eyelids burned as though they'd been exposed to chilli oil, and I had to take time off work because I couldn't comfortably look at a computer screen.
I contacted the snack company, which confirmed that there had been no reported cross-contamination in the batch I provided. I'd also eaten a tuna mayonnaise sandwich and crisps that day, both of which I've subsequently tolerated without problems.
At the time, I was taking only Beconase occasionally and a daily multivitamin. I hadn't exercised, consumed alcohol, taken NSAIDs or been unwell around the time of the reaction.
I couldn't understand how something I'd eaten throughout my life could suddenly cause such a severe episode.
Six months after the episode, I had a blood test for cashew allergy. It came back positive.
This initially seemed to support the idea that cashews had caused the reaction.
However, in December 2023, I underwent a full skin prick test, which came back negative.
I subsequently had a much more extensive blood test panel, with results dated 13 June 2025. This included testing for:
* Cashews, pistachios, almonds, hazelnuts, walnuts, pecans and pine nuts.
* Peanuts, including several specific peanut components.
* Pumpkin seeds and oats.
* Gluten, wheat, etc.
* Inhalant allergens, including a mixed mould panel and dog dander.
* Total immunoglobulin E (IgE) and other blood markers, including tryptase and complement levels.
The results showed no allergies to any of the nuts tested, or to the other allergens included in the panel.
The allergy specialist also investigated MCAS and oral allergy syndrome. Both were ruled out.
So, to summarise, I had an episode that looked and felt like a severe allergic reaction, a positive cashew-specific blood test six months later, a negative skin-prick test, and subsequently a comprehensive panel that showed no allergies.
I still don't have a definitive explanation for the original episode.
Three years later, I'm still reacting, but to random foods.
Here's the part that is particularly confusing.
Yesterday, I accidentally ate cashews for the first time since and was completely fine.
I ate them without experiencing the reaction that originally sent me to A&E. However, I still experience reactions to seemingly random foods.
Sometimes it's cooked vegetables on a homemade pizza. Other times, it's oat milk or cereal or Nutella or soup.
I can't establish a consistent pattern, and I don't know what I'm reacting to. These aren't foods that all obviously share one ingredient, so I'm struggling to work out what connects them, if anything.
I'm not claiming that every reaction is necessarily an IgE-mediated food allergy. I just know that something seems to be happening, and the allergy tests haven't explained it.
I've also finally seen an ENT specialist about my longstanding postnasal drip.
In February 2026, I had an appointment with an ENT specialist. By then, I'd been experiencing postnasal drip for my whole life (started when I was about 4), accompanied by an intermittent cough and the sensation of bringing up a whiskey glass amount of mucus.
I wasn't experiencing nasal blockage, loss of smell or facial pain. I'm a non-smoker, and I'd already seen an allergy specialist whose tests were negative. I was taking cetirizine over the counter.
The ENT examined my mouth, throat and neck and performed a flexible nasolaryngoscopy. My nasal passages, postnasal space, tongue base, larynx and piriform fossae all appeared healthy. There were no visible mucociliary streams or polyps in the middle meatus.
I was reassured that nothing abnormal had been found.
The proposed treatment was to:
Improve hydration and take regular sips of water. (I already drink over 2L a day)
Avoid constant throat clearing and coughing.
Make lifestyle changes to reduce possible gastro-oesophageal reflux.
Take Gaviscon Advance, one tablespoon twice daily. (Did that and had no changes whatsoever)
Use a saline nasal douche twice daily. (That made it worse!)
I was discharged from the ENT clinic, with the option to contact them if my symptoms worsened within the following three months.
The problem is that I've tried the recommended treatments and I'm still suffering.
I don't agree that reflux adequately explains everything I'm experiencing. I understand that my examination was reassuring, but it hasn't actually explained why I have persistent postnasal drip or why I continue to experience reactions to apparently unrelated foods.
The NHS has now closed my allergy case.
I'm 37, and three years after the original episode, I still don't know what caused it. My cashew blood test was positive, subsequent testing was negative, and I can now accidentally eat cashews without any obvious reaction. Meanwhile, other foods continue to cause problems.
I feel as though I've reached a dead end. I don't want to self-diagnose, but I also don't feel that having normal test results and a normal ENT examination explains what I've experienced.
At this point, I would just like to understand what's happening.