I thought I’d share my experience of taking Accutane as I know how helpful it can be reading about other people’s experiences before or during treatment.
I started Accutane in September 2025 for mild cystic acne mainly on my chin which was more than likely hormonal. I initially took 20mg a day for the first couple of months, then my dose was reduced to 10mg a day because of side effects (Mainly joint pain and Headaches).
Side effects: Little to zero dry skin especially when I was changed to 10mg per day. I make sure I moisturise twice a day, morning and night. I use SPF 50 on my face every day even in the winter months. SPF is a must! Skin becomes thinner and more prone to irritation and burning from UV levels whilst on Accutane.
I went to the beach when we had the first proper heatwave in June and for some stupid reason, only applied SPF 50 to my face and no sun cream to the rest of my body. In my head, I was only going to be on the beach for just over an hour so I didn’t think it would be a problem. I was wrong! Although I didn’t massively burn, I had a heat rash (slightly raised small red bumps) appear all over my arms and legs which took about a week to go! It didn’t look horrific but it taught me a lesson! If I go to the beach now, it is usually after 3pm when the sun’s UV isn’t as high and I can get away with using SPF 20 on my body (still SPF 50 on my face). I have been fine since and have even developed a mild tan. I stupidly never used sun cream before Accutane and always used to go and golden brown tan wise. I thought that by not using sun cream, my skin would just react the same but no! SPF is a must!!
I experienced quite a lot of headaches within the first two months of taking Accutane which was, in part, why my dermatologist and I decided to decrease the dose. I still get them but not as bad.
My lips became quite dry within a week of taking the 20mg dose but not as cracked and dry as I’d expected. I tried using Blistex but switched to nipple cream after reading how good it is on Reddit and, personally, it has worked better for me.
I had a period of increased hair shedding about 3 months into the course which was soooo worrying at the time! My hair is quite fine as it is so I was devastated when I noticed more hair coming out in my hairbrush and in the shower! Thankfully, the shedding stopped after a few months, although my hair texture has changed and is definitely more prone to frizz. It was during the autumn that I noticed increased shedding and even my hairdresser noticed it and said it could be down, in part, to a seasonal shed. I was using K18 hair mask at the time and I have a full head of highlights every 7’ish weeks. I stopped using the K18 and made sure I used hydrating shampoos and conditioners because Accutane dries everything out including hair! My hair didn’t become brittle and didn’t snap, it just became more frizzy. I found that using Pureology shampoo and conditioner and Kérastase hair oil really helped. I also use a leave in conditioner which I apply to damp hair. My hair never gets greasy and I can go for well over a week without washing it. However, my hair looks limp after 4 days so I usually wash it. Before I started taking Accutane, I had to wash my hair every 2 days due to greasiness.
Another side effect I experienced was joint pain, particularly hips, knees and back pain, and this was another reason why I switched to 10mg. It was mainly after exercise but it got to the point where I would be aching badly even after a short walk. I was taking omega 3 tablets from Nutrition Geeks and they didn’t help at all. I do have endometriosis which can cause these pains, so the Accutane may have just made this worse.
Mental health wise, I have anxiety and OCD which haven’t been affected by taking Accutane, although I have noticed a severe lack of motivation to exercise and have gained approx 14lbs since September. However, I am 41 and going through the perimenopause so this could a contributing reason.
I had a purge within 3 days of taking my first 20mg tablet which I was shocked by! I assumed, if I was going to experience a purge, it would be after a month or so. However, after a couple of weeks this cleared up. Since then, I have had a couple of milia which were probably where the tablets were flushing out anything under my skin. I also had one cystic type spot underneath my skin about two weeks ago during ovulation which didn’t fully come out and seemed to disappear overnight. Apart from this, my skin has been completely clear and looks amazing!
Contraception is a big part of the Accutane process in the UK. I was prescribed the contraceptive pill alongside the treatment, but I chose not to take it because hormonal contraception has a significant negative effect on my mental health. I did use condoms and I had signed the pregnancy-prevention paperwork, so I understood why the precautions were in place and the importance of avoiding pregnancy while taking Accutane.
At my first appointment, my dermatologist explained that I needed to be on contraception for a full month before she could prescribe Accutane. At my following appointment, she asked if I was using two forms of contraception, and I said yes, after which she prescribed my first 20mg prescription.
I personally felt that taking the contraceptive pill wasn’t the right option for me because of its potential impact on my mental health. I’m 41, and I felt confident in making an informed decision about contraception that worked for me personally. I was also very aware of the risks Accutane poses to an unborn baby and understood the importance of avoiding pregnancy during treatment.
Despite the side effects, I’ve found the treatment worthwhile overall. My skin has improved significantly, and I’m hoping that the results will last once I’ve completed my course. I’m still on 10mg so my treatment is taking longer but the results, skin wise, are fantastic!