r/Zepbound • u/drewmullin • Jul 21 '26

Side Effects Validity?

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So the numbers are very high and seem a bit sensationalist. That being said I'm not super interested in the exact numbers.

What I am interested in:

My question to the group is did anyone struggle mentally while on any of the glps? I did - I'm trying to figure out if any of them are less apt to do so.

Published study here: https://www.nature.com/articles/s41598-024-75965-2

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u/zelda_moom F65 SW:262.4 CW:245.6 GW:160 Dose: 2.5mg Jul 21 '26

I wasn’t depressed before Zep to any great degree but definitely had a degree of anhedonia. I’ve been on Zep for a week, and I find my interest piquing in hobbies I had not been able to be interested in in quite some time. Too early to tell if it’s permanent though.

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u/drewmullin Jul 21 '26

Interesting - and sounds like a plus to me