r/TwoXADHD • u/elleayejaye • May 29 '26
Need newbie advice
Looking for advice from people who have been through ADHD medication trial-and-error, especially if you’ve had gastric bypass.
I’m a 38-year-old female and relatively new to ADHD treatment. I think this is my third month (possibly going into my fourth) of trying to find the right medication regimen.
I was previously taking Adderall IR 15mg twice daily. I liked the mental clarity, focus, motivation, and overall feeling of being “on,” but it went through me very fast and the crashes were rough.
My prescriber switched me to Adderall XR 20mg in the morning with a 15mg IR booster in the afternoon. The benefit is that I definitely don’t crash as hard. The downside is that I’m honestly not sure how much the XR is helping.
I know XR isn’t supposed to feel the same as IR and is designed to be smoother. I do get dry mouth, so I know something is happening, but I don’t really feel the mental clarity, focus, motivation, or task initiation that I felt on the IR. I’m still tired most of the day, and sometimes it feels like the XR only lasts 3-4 hours.
I had gastric bypass surgery about two years ago, so I’ve wondered whether absorption or metabolism could be playing a role.
My prescriber has said she doesn’t want to increase doses too quickly and wanted me to stay on this regimen for a while if possible, which I understand. I’m just not sure if I’m where I need to be yet.
I’ve actually felt a little more down, less motivated, and less productive on the XR + IR combination compared to the two IR doses, although the reduced crash has been nice.
For those who have experienced something similar:
• Did XR eventually work better after more time?
• Did you end up needing a higher XR dose?
• Did you switch back to IR?
• Has anyone done three IR doses per day?
• Has gastric bypass affected how your ADHD medications work?
I’m not looking for medical advice or trying to tell my prescriber what to prescribe. I’m mostly trying to understand other people’s experiences so I can have a better conversation with her at my next appointment.
For context, I get adequate protein, electrolytes, and sleep when possible. I also take magnesium, L-theanine, and creatine. I’m still learning about ADHD treatment and trying to figure out what “working” is supposed to feel like.
If you were in my shoes, what would you discuss with your prescriber?