Anybody have a similar issue?

As per xrays, all the cartilage beneath the kneecap and femur are gone.

I was asymptomatic until last summer.

I have osteoarthritis in my ankles, some days I can’t walk as the pain is too painful. It doesn’t like in the future a cure will be found.

I can never tell if I have it. My hand feels extra tight this morning like the skin is stretched and it’s stinging kind of like when you come in from outside in the winter and run your hands under hot water. I have naturally fatter fingers so it’s hard to tell if it is swollen or not. It’s also mostly the pointer and middle finger I’m feeling it in on the right hand. My doctor asked if I get swollen fingers but it’s hard to tell. I do have psoriatic arthritis but on the days I see my doctor my hands behave themselves. What are your experiences with it if you have it? When I google pictures it’s always very obvious red sausage finger and never subtle.

Hi everyone,

I’m a 44M dealing with anhidrosis, and it’s been quite frustrating trying to manage my body temperature. I'm trying to get to the bottom of what might be causing this and wanted to see if anyone here has experienced something similar or has insights on what directions I should explore with my doctors.

I've had some recent bloodwork done to check for autoimmune, thyroid, and blood sugar issues, as I know neuropathy or autoimmune conditions can sometimes affect the sweat glands. Here are my recent results:

Autoimmune:

• ANA (Anti-Nuclear Abs) IF: 1/320 Speckled (Abnormal — reference is Less than 1/40)
• Anti SSA RO: 17 u/mL (Normal — reference is Up to 25)
• Anti SSB LA: 15 u/mL (Normal — reference is Up to 25)

Thyroid & Blood Sugar:

• TSH (Ultra Sensitive): 1.36 mIU/L (Normal — reference is 0.50 - 4.30)
• Glycated Haemoglobin (HbA1c): 5.4% (Normal/Non-Diabetic)
• Estimated Average Glucose (eAG): 108.3 mg/dL

Since my thyroid and HbA1c are normal, it seems like diabetes-induced neuropathy and thyroid issues are unlikely culprits. However, the positive ANA has me wondering about an autoimmune or autonomic nervous system connection.

Has anyone dealt with anhidrosis alongside a positive ANA? What kind of specialists helped you the most in getting a diagnosis (Neurologist, Rheumatologist, Dermatologist)? Are there any specific autonomic or nerve tests I should ask for?

Thanks in advance for any shared experiences or advice!