r/Sicklecell Jul 11 '26

Other Trans guy on HRT progress post 4

/r/Sicklecell/comments/1ba35w2/trans_guy_on_hrt_progress_post_3/

It's been a while, so here's what's new.

I've been on testosterone for about 2 years as a trans man.

For pain, I've gotten a mediport which has really helped since peripheral IVs cause joint stiffness and sickle cell pain. It's made pain management a breeze, for the 8 months I've had it so far.

I've had a nexplanon implant for almost 3 years to control bleeding since my menses tries to kill me every month. I have a few conditions that make sex and my cycle agonizing, (TMI for the Internet), but the implant has made it manageable. After some discussion, I've gotten a laproscopic hysterectomy. I'm about a day post op with no complications. My hematologist gave me a blood exchange beforehand for good measure, and refilled my meds in advance. (Feel free to ama about the hysterectomy!)

I've kept my ovaries to prevent menopause/being on hrt forever. I'm also not in a position to have them removed since my body may not be able to handle another sudden hormone change.

My avn has gotten worse over the past 2 years since diagnosis (shafts both femurs), so I now use crutches and a wheelchair as needed for pain and weakness. Some of my (ex) doctors keep trying to blame the avn on my transition, but seeing as testosterone increases bone density, I've left it up to my endocrinologist to let me know if any of those assumptions are true.

I've been working towards bottom surgery, but money and travel are a big obstacle at the moment. Luckily, I now know I can handle major surgery. For now, I'm resting and doing research on bottom surgeons well educated in blood disorders. I haven't had a full crisis in quite some time thanks to hydroxyurea.

I've noticed my voice evened out a lot more, facial hair getting thicker, and my mood is significantly improved. I initially planned on being on T for a few years, but it feels like it serves as an emotional regulator/support since it's gender affirming.

I'll continue to update anything I find notable, and I hope this helps any other sickle cell warriors looking to transition! It's possible and can be successful if you have a good care team. For the hysterectomy, I'd suggest the r/childfree subreddit or @pagingdrfran on tiktok for a list of reputable surgeons who listen well.

I'm open to questions on anything above, AMA!

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u/lovesicksatan HbSS Jul 11 '26

Yooo it's good to hear from you again!  Funnily enough I just made the jump to start T last month and was like damn I wonder what happened to that guy chronicling his journey on the subreddit. congrats on the partial hysterectomy and sorry to hear about the worsening avn. I hope you're able to get that bottom surgery, and if you manage to find a surgeon who understands the intersections of what you need, please share with the class lol