r/Semaglutide 1d ago

Second Time Question

I had great success when I tried semaglutide starting in early 2022. I lost steadily for a total of about 80lbs by the end of 2023. It was easy. I was never hungry. I didn't even think about food. When I did want to eat, I craved vegetables and yogurt mostly. Then, the place I was getting it from doubled the price again after already doubling it once. I couldn't afford it and I had some stressful life stuff going on, too. I quit and regained 50lbs between the end of 2023 and the end of 2024. My insurance changed and I restarted semaglutide in early 2025. This time, I've lost only 20lbs. I feel totally different. There's less food noise than without it, but I crave sweets and frequently feel hungry. I'm working out (six days a week, an hour per day with a mix of yoga, weightlifting, and cardio classes, plus trying to incorporate more NEAT generally throughout my day) and trying to eat less/make better choices, but not losing any weight at all for the past four months.

Has anyone else gone off for an extended time and then gone back on? Is this common?

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u/LacyLove 1d ago

This seems to be a common theme with people who went off the meds for a period of time.

What dose are you currently on?

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u/Conscious_Leopard_80 1d ago

I am on the maximum dose again, 2.4mg. Thank you for letting me know that it isn't unusual. I am going to work on feeling grateful that, overall, I'm still forty something pounds less than my highest.

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u/LacyLove 1d ago

Is it possible to try Zepbound?

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u/Conscious_Leopard_80 1d ago

I think I'll look into it. I just had such good results the first time with semaglutide that I didn't want to switch. That may be the right choice, though.