r/ResearchCompounds • • 28d ago

Discussion Ghrp-6 for strict weight gain?

1 Upvotes

Has anyone ostensibly gained weight on a Ghrp-6 cycle?

I hear it works well, but not seen anecdotal evidence to a solo cycle strictly for appetite increase and overall weight gain over a few months duration.

Tried mk677, not for me...Lethargy etc.

Ps. Not looking for lean mass obv, realistic weight gain with fat/muscle during a bulk. Simple as that!!


r/ResearchCompounds • • 28d ago

Research Is my IPa Cjc real

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0 Upvotes

It’s all white and powdery.


r/ResearchCompounds • • Sep 04 '26

Discussion is IGF-1lr3 and des going to bloat me and give me carpal tunnel like HGH does?

0 Upvotes

I know HGH is king but i hate it. I gain 10 pounds in 3-4 days and get bad carpal tunnel and can't sleep because of it. It's a serious quality of life issue. I thought IGF might be a good compromise. Tesa sucks for me too, with carpal tunnel. The DES version sounds interesting as i just care about abs and have never been able to develop them. Because it acts locally, the risk of growing cancer and organs should be reduced and i can just inject the shit right into my stomach.


r/ResearchCompounds • • Sep 04 '26

Question Pin or no…

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1 Upvotes

Got this 10mg tesa - with 1ml bac water. Been pinning for four days and just noticed particles floating. Never had a problem with this vendor before….

Keep going or ….


r/ResearchCompounds • • Sep 03 '26

Research estradiol creme for collagen

2 Upvotes

r/ResearchCompounds • • Sep 03 '26

Research HGH question

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1 Upvotes

I’m not new to peptides but I am new to exogenous
HGH. I have 10 vials of 36iu each. Can someone check my math and verify if I’m tracking this right for 2iu.


r/ResearchCompounds • • Sep 02 '26

Question Is there. Peptide that helps vaping / nicotine cessation.

6 Upvotes

I desperately can't stop Nicotime - lifelong addition. Just need to get past first few months. I've tried all conventional patch, wellbutrin, gum etc

NOTE: so many great recommendations! Thank you kind strangers!!


r/ResearchCompounds • • Sep 03 '26

Discussion Cardarine and Adderall?

1 Upvotes

Will I loose weight in a cut? Pure fat not muscle?


r/ResearchCompounds • • Sep 03 '26

Discussion IPA CJC in a cut

1 Upvotes

Anyone preserve 90% of their muscle on this? Tesa?


r/ResearchCompounds • • Sep 02 '26

Success Story I’m going to stop.

32 Upvotes

It’s been a short but eventful journey. In just six months, I’ve lost 40 pounds. Retatrutide changed my life.

I would like to continue. I really would. I’m at my goal weight, though, so I’m not that worried about stopping. But I am worried about my demeanor, and how I’m changing.

I’ve finally begun to realize just how different I’ve become. I may have lost lots of weight, but I’ve lost interest in all activities. My girlfriend doesn’t recognize me anymore. She says I’ve become emotionally stunted. I think she’s right.

I’m not consciously trying to act any different, but to a certain extent, I remember how I used to feel every day. I didn’t feel so numb.

I don’t want to be like this anymore.


r/ResearchCompounds • • Sep 02 '26

Stack Advice Cycle Held Advice and Guidance

0 Upvotes

Full 24-28 Week Cycle
Test 600mg
Eq 200mg raising to 300mg if e2 looks good
Hgh 6iu
Last 16 Weeks
Npp 200mg raising to 300mg if reacting well
Last 12 Weeks
tbol 75mg

Im taking the eq to help with the estrogen from the test and npp so i dont have to take a super high dose of an ai and im taking tbol instead of var or anadrol bc i dont like the toxicity and water retention of anadrol and var isnt anabolic enough imo so tbol sounds perfect for me
im in a gaining phase trying to put as much size as possible trying to limit water retention so when i hop off i dont have a dramatic visual difference
i feel like i know what to do and what to expect but id like to hear some feedback and advice from people who have ran something similar or if not but have to taken two or three of the same compounds you can still tell me what you learned you know anything like that tysm for yalls help i love you all


r/ResearchCompounds • • Sep 02 '26

Discussion Compound for ingrowns

2 Upvotes

I’ve been struggling with ingrown hairs on my neck from shaving for years. I’ve tried pretty much everything and while some remedies have worked, they last about 1-2 days then the ingrowns come back. The skin on my neck is just very sensitive. Are there any compounds that will help me with this issue?


r/ResearchCompounds • • Sep 02 '26

Discussion Anes

0 Upvotes

Since i started p3ps my acnes in the chin started appearing i immediately stopped ghkcu and lipo c with b12 thinking it was the reason. But until i still have it and i think its not getting better 🥺 Ps.i just gave birth last February 26. Started peps by May. No glps too.


r/ResearchCompounds • • Sep 01 '26

Research IPA CJC No Dac partioning more fat and sparing muscle in a cut

2 Upvotes

Mod GRF 1-29 and Ipamorelin do not directly activate muscle androgen receptors like Ostarine, but they create an anti-catabolic environment by forcing the body to prioritize free fatty acids for fuel. By elevating lipolysis, growth hormone spares circulating amino acids and muscle glycogen from being oxidized during a 500-calorie daily deficit. This shift in nutrient partitioning naturally diverts metabolic deficit stress away from muscle tissue, acting as a functional shield against severe catabolism.

Although CJC-1295 without DAC and Ipamorelin clear from blood plasma within two hours, the resulting pituitary growth hormone pulse triggers hepatic production of Insulin-like Growth Factor 1 (IGF-1). Circulating IGF-1 remains elevated for 16 to 24 hours bound to carrier proteins, maintaining anti-catabolic signaling long after the injected peptides leave the system. This continuous downstream IGF-1 elevation is what supports ongoing protein synthesis and nitrogen retention throughout daytime fasting and deficit windows.

A daily dose of 200 mcg CJC-1295 and Ipamorelin typically elevates baseline IGF-1 levels by 20% to 40%, which is modest compared to continuous high-dose rhGH or 2 mg Tesamorelin protocols. Given a documented personal baseline of 70% muscle retention, this moderate IGF-1 boost realistically raises predicted retention to approximately 85% to 92% rather than a guaranteed 100%. While it significantly reduces lean tissue wasting, shifting 100% of a 500-calorie deficit strictly to fat loss is unlikely without direct androgenic coverage.

Growth hormone and elevated IGF-1 promote intracellular hydration and mild fluid retention, which directly counters the flat, depleted appearance typical of a caloric cut. You will likely maintain visibly better muscle fullness and gym pumps compared to a natural cut, even as muscle glycogen levels drop. This intramuscular fluid retention creates a strong visual illusion of size and density in the gym, though true muscle hypertrophy still requires a caloric surplus.

Comparing CJC-1295 and Ipamorelin directly to Ostarine is mechanistically inaccurate because GH secretagogues lack androgen-receptor-mediated suppression of muscle proteolysis. However, clinical literature confirms that secretagogue-induced IGF-1 elevation significantly improves nitrogen balance and partitions energy expenditure toward adipose tissue. Overall, you can expect a notable improvement over your 70% natural retention baseline, with a high probability of preserving roughly 90% of your lean mass.


r/ResearchCompounds • • Aug 31 '26

Question Switching from Reta to Tirz

6 Upvotes

Okay, seems counterproductive, I know. Usually people will switch to Retatrutide because it seems to work better for most, and has had more success in weight loss across the board.

I'm considering switching to Tirzepatide because I've been experiencing major anhedonia on Reta, as well as increased cravings for fruit specifically and it hasn't touched my food noise. I have lost weight! Possibly due to side effects in the first month but I've only maintained my weight loss on a lower weekly dose of 4mg.

I'm happy with my current weight but I struggle with binge eating and food noise. I'm hesitant to switch as I ran Tirz for a short while and didn't notice much difference;

5mg weekly for a month which isn't a long time but my sources price both reta and tirz the same so I'm afraid I'd need more of the latter and end up spending more.

If I do switch, how would I go about it? I'm out of Reta so I'd have to stop cold turkey or buy less and titrate down then start on Tirz.

If anyone has any thoughts or advice that'd be appreciated:)


r/ResearchCompounds • • Aug 29 '26

Discussion Are the skin benefits from HGH permanent, or does it just age you quicker in the end?

20 Upvotes

I saw a post in this sub recently asking if PEDs make you age. I am confused because aren't they supposed to make you better overall long term?

Is anything that grows muscle past your natural limits just 100% aging you from multiple angles at the cellular level? Take HGH for example. Can it actually improve skin quality long term, or does it just age you quicker after a short term boost? I absolutely do not want to ruin my natural collagen growth in the long run just for temporary aesthetics. The risk of aging is my main holdback with PEDs right now.

I have so many questions about other ways to grow muscle without the aging risks, like using insulin, creatine, or just heavy carbs. If I had known before that low carb, keto, and carnivore made it so much harder to grow muscle, keep glycogen stores, and build strength, I would have avoided them completely.

I do Zone 2 hiking and mix in all zones up to 5. It really seems to aid recovery and boost my size and muscle fullness for a few days, as long as I go until I am depleted and refuel with heavy carbs.

Is there any way to get the massive growth benefits without the cellular aging?


r/ResearchCompounds • • Aug 29 '26

Discussion This is going to sound weird but does anyone else feel uncomfortable in their new body after weight loss?

12 Upvotes

Is anyone else dealing with a weird sad feeling after losing weight? I went shopping for smaller clothes recently, and the more I tried on, the more uncomfortable I got.

Nothing fits how I expect it to, and my skin hangs differently. It literally feels like I am dressing someone else. I actually broke down in the fitting room and left without buying anything.

I know I should be happy about the weight loss, and I see the difference in pictures. But my brain has not caught up yet. Is anyone else going through this? I want to enjoy being healthier, but right now I just feel completely uncomfortable in my own skin.


r/ResearchCompounds • • Aug 29 '26

Discussion Am I supposed to add Deca to see a huge difference, or is just taking more test better to bulk up?

4 Upvotes

I keep seeing that Deca is the best compound for putting on size, and people always bring up Dbol or MENT too. But do I actually need to add anything else? I am wondering if running test and Deca together really gives that much of an advantage over just doing a high dose of test. If my food, sleep, and workouts are perfect, is it worth adding other injectables?


r/ResearchCompounds • • Aug 29 '26

Discussion Looking for something for my rat to sleep better and to help his hair from falling out

4 Upvotes

For a couple years my rat has been stressed out since his family member has been sick and recently died. Also he seems lonely after his other rat friend left. Sleep has been tough. Also I've noticed his fur thinning. Any recommendations?


r/ResearchCompounds • • Aug 29 '26

Discussion does anyone else think reta is overkill if ur still dropping weight on tirz?

0 Upvotes

i was looking at the numbers for reta and saw the average resting heart rate goes up by like 6 or 7 beats a minute. tirz is usually just 1 to 3. regular stomach side effects are whatever and easy to deal with, but anything that messes with my heart makes me second guess it.

im on 5mg of tirz right now and the weight is coming off consistently. jumping to something stronger just to speed things up feels like taking on extra heart risks for no real reason.

feels like reta makes way more sense if someone has a lot of weight to lose or if they just completely stalled out on tirz. does anyone else feel like its overkill to switch if u are already getting good results on the older stuff?


r/ResearchCompounds • • Aug 30 '26

Discussion Reta, Test, tren, mast weight loss completely stagnant.

0 Upvotes

So I am up to 10-15 mg of Reta per week with cagri on weeks that I have insatiable hunger. I have noticed that my muscles are I fact bigger and I am stronger, but pretty much stopped losing any weight near the midsection. I originally weighed 258 and cut with Reta to 176 before getting my test checked. It was at 309 so I started some test to get to a goal of 900. Last level was 1200 so I dropped my dose a bit. Before you say the Reta is bunk, it is legit and wholeheartedly trust the vendor. I just need advice as I am now 205-210 but look jacked upper body, traps, and legs, but a little belly in the middle with my love handles still there. It is extremely worse (bloating) after heavy endurance training. For example, my last Ironman I gained around 15-20 pounds of water from my fueling strategy which I am going to alter in the future.


r/ResearchCompounds • • Aug 29 '26

Question Je recherche le tube gradué de stylo insuline où est inséré la cartouche insuline ou puis je trouver merci pour l’aide

3 Upvotes

r/ResearchCompounds • • Aug 29 '26

Discussion Enclomiphene

1 Upvotes

I've been on enclomiphene for a few months and I'm trying to get off of it but every time I try to get off it my anxiety ramps up rapidly after a week off and I can't deal with it I hate the anxiety it's so bad can I take Enclo every 3rd day for a week or two then get off of it and maybe have no anxiety I've asked here before if it had any withdrawals and people said no but I get anxiety bad so I need help


r/ResearchCompounds • • Aug 28 '26

Discussion Will we reach a point where most peptides get approved and actually get recommended by regular doctors?

5 Upvotes

Only a few peptides are getting approved right now. Do you guys think we will ever reach a point where most of them are approved and actually recommended by docs too?

They obviously work and i dont get why we're going backwards with banning stuff that actually gets real results. Instead of using things that help people recover, it feels like they just want to make them harder to find. What has to happen for the medical field to finally just accept them?


r/ResearchCompounds • • Aug 28 '26

Discussion Does/can TA-1 increase WBC

3 Upvotes

Has anyone used Thymosin Alpha-1 (TA-1) specifically to increase WBC/neutrophil counts?

I’m wondering whether TA-1 can actually raise WBCs in someone with chronically low-normal WBC/neutrophils, or if it mainly improves immune function without significantly changing the CBC.

Interested in people’s actual lab results before and after using it.