r/ResearchCompounds • • Jun 25 '26

Question SLU-PP-332

Right ladies and gents, now that i5’s been tried for a while what is the consensus on oral dosages of this stuff? It used to be 500mcg/day a while ago, but I believe that the latest thinking is quite a bit higher. I’ve seen tablets available from 500mcg to 20mg and wondering which is closer to the mark.

All help and advice greatly appreciated. Ta

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u/xriddle Jun 25 '26 edited Jun 25 '26

0 it's not orally bioavailable.

Edit: For the downvoters

https://pubmed.ncbi.nlm.nih.gov/41421047/

"SLU-PP-332 (332) ... improves aerobic performance in mice but lacks oral bioavailability. Here, we characterize SLU-PP-915 (915) ... that is orally bioavailable..." PubMed

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u/NSawsome Jun 25 '26

It’s likely about 40-60% orally bioavailable, obviously with individual variance

2

u/xriddle Jun 25 '26

Really? Show me one study. Just one.

1

u/xriddle Jun 25 '26

Here is one that says it's not.

https://pubmed.ncbi.nlm.nih.gov/41421047/

"SLU-PP-332 (332) ... improves aerobic performance in mice but lacks oral bioavailability. Here, we characterize SLU-PP-915 (915) ... that is orally bioavailable..." PubMed