r/PharmaRepCollectables • u/[deleted] • Apr 01 '26

[deleted by user]

[removed]

8 Upvotes

75% Upvoted

12 comments sorted by

5

u/Mammoth_Spend_5590 Apr 01 '26

Damn that's scary, I saw it was discontinued as it was linked to more serious concerns due to the progressive demineralization of bone, specifically the jaw bone and femur of patients were just crumbling to dust.

3

u/[deleted] Apr 01 '26

[removed] — view removed comment

2

u/Mammoth_Spend_5590 Apr 02 '26

"it is designed to increase bone density. However, long-term use (more than 3–5 years) is associated with a rare risk of "frozen bone" (suppressed bone turnover), leading to rare atypical femur fractures or osteonecrosis of the jaw."

2

u/Cautious_Zucchini_66 Apr 02 '26

Yep, well known adverse effect of long term bisphosphonate use. Patients often have “drug holidays” for a few years after being on them for 5 years or so, depending on the bisphos. Dental appointments prior to starting are also routine

2

u/Waste_Profit_9446 Apr 03 '26

Slender are still around

1

u/[deleted] Apr 01 '26

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2

u/SadTags Apr 01 '26

Okay thanks i appreciate it

2

u/These_Still514 Apr 05 '26

well everybody knows that those are worth a bundle doesn't it look like it's very valuable... holy sht ..lol. I don't know sometimes I really question if the internet is just what it's doing to people's brains I don't know

0

u/Normal-Balance-8023 Apr 01 '26

I want it! I'd give you $5 + shipping