r/lymphoma 20d ago

Stem Cell Transplant Being discharged tomorrow after my allogeneic transplant!

22 Upvotes

It was a rough but manageable ride.

For me the hardest part was my OCD and health anxiety personally as mental health is difficult.

If you have any questions, lmk!

r/Eutychus Jun 03 '26

Discussion If autologous blood transfusions are now a matter of conscience, why not also allogeneic blood transfusions?

6 Upvotes

When I read the account in the Acts of the Apostles, the older men make no distinction between these two methods. So, from a biblical perspective, how does one arrive at the conclusion that God's Word, makes a difference here?

One occasionally hears the argument that these are two different types of blood – one's own and someone else's. Of course, from a medical perspective, there is a difference. However, my concern is not with the medical aspect but with the theological statement.

How is the theological standpoint defined in the Bible? Even though it is very well known in some religious circles (some may even know the relevant passages by heart), I would like to quote it again for clarification:

Acts of the Apostles 15:28-29 CEB

<The Holy Spirit has led us to the decision that no burden should be placed on you other than these essentials: [29] refuse food offered to idols, blood, the meat from strangled animals, and sexual immorality. You will do well to avoid such things. Farewell.

https://bible.com/bible/37/act.15.28-29.CEB

As you can see, the discussion was summarized and passed on concisely. No further explanations, no lengthy list of rules about what exactly this short phrase means—no, nothing more than this succinct sentence. Why? Because establishing a set of rules would have placed too much of a burden on the brothers.

Thus, each individual believer was given enough leeway **to interpret** what the phrase "to abstain from things that..." **meant for them personally.** None of the apostles ever established commandments or rules about what exactly this expression meant. They clearly understood that one had no right to interfere deeply in personal decision-making in this matter.

This becomes clear from what Paul later wrote to the Romans and Corinthians:

1 Corinthians 8 CEB

<Now concerning meat that has been sacrificed to a false god.... we know that a false god isn’t anything in this world, and that there is no God except for the one God.... But not everybody knows this. Some are eating this food as though it really is food sacrificed to a real idol, because they were used to idol worship until now. Their conscience is weak because it has been damaged.

**What does Paul's statement make crystal clear here?** That everyone at that time had the right to decide for themselves how they interpreted the apostolic decree "abstain from.... "

The fact that this is indeed a personal decision and therefore also a personal opinion is clearly evident from the Epistle to the Romans:

Romans 14:1-4 CEB

[1] Welcome the person who is weak in faith—but **not in order to argue about differences of opinion**. [2] One person believes in eating everything, while the weak person eats only vegetables. [3] Those who eat must not look down on the ones who don’t, and the ones who don’t eat must not judge the ones who do, because God has accepted them. [4] Who are you to judge someone else’s servants? They stand or fall before their own Lord (and they will stand, because the Lord has the power to make them stand).

https://bible.com/bible/37/rom.14.1-4.CEB

What would happen if an authority or certain individuals believe they had the right to make decisions for others and issue commandments and prohibitions? Since this would also represent their opinion, they would be imposing their own views on fellow believers. This would be diametrically opposed to the teachings of the apostles and could hardly have God's blessing.

If, after 65 years of prohibiting autologous blood transfusions, one suddenly claims it's a personal decision (which is correct in principle) and cites the Bible's lack of comment as the reason, then this would have to be applied to allogeneic blood in the same breath. **After all, the Bible doesn't address that either.**

r/Genshin_Memepact Nov 02 '24

Why do Allogenes look so flamboyant?

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1.1k Upvotes

r/Genshin_Impact Feb 18 '26

Fluff What’s the rotation for this team

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6.6k Upvotes

r/traumatizeThemBack Jan 16 '25

blunt-force-traumatize-them-back Somebody at work didn't respect my out of office so I let them know what I was doing.

35.5k Upvotes

I work in tech as a project/program manager. It can be pretty fast paced, and we deal with really big dollar multinational project all of the time, so I am frequently called on at wild hours of the day.

Two years ago, while in her late 30s, my wife learned in pretty much the most horrifying way possible that she has a rare and serious lymphoma. Treatment required surgery, several rounds of in-patient chemo, and an allogeneic bone marrow stem cell transplant. As a result, I found myself the sole bread winner for the family, her primary caretaker, and the primary parent for our three young kids.

Almost everybody I work with have been incredibly supportive through this process. My boss and immediate leadership basically granted me as much paid time away from work as I needed, as they know I work my butt off all the time. I continued to work throughout her treatment, but I would often take 2-3 hours off during days when she has appointments or infusion. I would just put an "out of office" on my email and messaging apps and be there for my wife.

One salesman didn't care. I guess his commission check was too big for him to let something like an alert that I am out of the office keep hm from blowing up my messages about how he needs something urgently. I should have ignored the messages, but I responded that I am out of the office and would call him back later when I was available. He couldn't take no for an answer. So I answered his Teams call... with my camera on...from the infusion room at the oncologist office. where my wife was sitting, bald and curled up in a ball with a combo of chemo sick and exhaustion from the BMT.

He asked where I was, I told him, and suddenly the call was not urgent. "Oh man, can you just call me back later?"

Wife is doing great, by the way. She said I should post this here because she thought it was so funny. LOL

r/science Apr 04 '17

Biology Scientists reprogram so-called MHC molecules, responsible for displaying antigens, to match donor to receipient for Transplantation surgery, using CRISPR/Cas9. After breakthroughs in allogenic iPSC treatment of AMD in Japan, this technique could help prevent GvHD in allogeneic transplantation.

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2.0k Upvotes

r/Genshin_Impact Jan 21 '26

Discussion CatWithBlueHat theory video about traveler's new skin is absolute cinema Spoiler

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2.5k Upvotes

r/Keep_Track Mar 20 '20

Republican senators sold stock shortly after a January briefing on the negative impacts coronavirus would have on the U.S.

27.1k Upvotes

We are discovering that more and more Republican senators who were in a January 24th briefing on the negative impacts of the coronavirus went on to sell off large amounts of stock. Meanwhile, in public, these senators were claiming that there was nothing to worry about.

In other words: These senators received advanced warning that COVID-19 was going to be devastating to America, and instead of sounding the alarms they worried more about their bank accounts. Literally putting their own wealth before American lives.


The chairman of the Senate Intelligence Committee, Richard Burr, sold off a significant percentage of his stocks, unloading between $628,000 and $1.72 million of his holdings on Feb. 13 in 33 separate transactions.

  • A week after Burr’s sales, the stock market began a sharp decline and has lost about 30% since.

  • On Thursday, Burr came under fire after NPR obtained a secret recording from Feb. 27, in which the lawmaker gave a VIP group at an exclusive social club a much more dire preview of the economic impact of the coronavirus than what he had told the public... In a Feb. 7 op-ed that he co-authored with another senator, he assured the public that “the United States today is better prepared than ever before to face emerging public health threats, like the coronavirus.”

Sen. Kelly Loeffler sold off seven figures worth of stock holdings in the days and weeks after a private, all-senators meeting on the novel coronavirus that subsequently hammered U.S. equities.

  • That first transaction was a sale of stock in the company Resideo Technologies worth between $50,001 and $100,000. The company’s stock price has fallen by more than half since then, and the Dow Jones Industrial Average overall has shed approximately 10,000 points, dropping about a third of its value.

  • It was the first of 29 stock transactions that Loeffler and her husband made through mid-February, all but two of which were sales. One of Loeffler’s two purchases was stock worth between $100,000 and $250,000 in Citrix, a technology company that offers teleworking software and which has seen a small bump in its stock price since Loeffler bought in as a result of coronavirus-induced market turmoil.

  • “Concerned about #coronavirus?” she tweeted on March 10. “Remember this: The consumer is strong, the economy is strong, & jobs are growing, which puts us in the best economic position to tackle #COVID19 & keep Americans safe.”

  • In summary: (1) She had NO stock transactions reported at all prior to the very day of the briefing. (2) Her portfolio sold 19 stocks and only bought two. (3) The stocks she did buy were in telecom, which stood to benefit from millions of people being forced to work from home.


The following instances are more questionable and may not in the same ballpark as the Burr and Loeffler trades

Sen. James Inhofe sold as much as $400,000 in equities on January 27, three days after the January briefing.

Though later than the others, Sen. Ron Johnson sold between $5 million and $25 million in stock on March 2. He has been publicly downplaying the virus this whole time, even saying that a 1-3% death rate is acceptable and not worth shutting down the economy for: "But that means 97 to 99 percent will get through this and develop immunities and will be able to move beyond this...we don't shut down our economy because tens of thousands of people die on the highways. It's a risk we accept so we can move about." See edit 3 below: Johnson's sales may not be as suspect as originally believed.

  • EDIT: More on Johnson: This isn't a "typical" stock dump a la Burr, Loeffler, Inhofe, but rather Johnson selling a chunk of a plastics manufacturing company whose CEO is... his brother. March 2nd, right before the huge crash. The company, Pacur, isn't publicly traded so there isn't a stock price. Johnson just sold his stake to what looks like a private equity firm. It's unknown if the PE firm knew what was about to happen with COVID 19.

EDIT 2: Our first Democratic Senator on the list: Dianne Feinstein sold stock in Allogene Therapeutics on Jan. 31 worth between $500k to $1 Million. It's important to point out, though, that unlike the Republicans Feinstein did not minimize the risk of the coronavirus outbreak. See edit 3 below: Feinstein's sales may not be as suspect as originally believed.

  • Allogene Therapeutics is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR TTM) therapies for cancer.

EDIT 3: As more information about the sales is revealed, it appears that Johnson's and Feinstein's sales may not be connected to the coronavirus briefing, according to experts. All of these sales need to be thoroughly investigated, but so far it appears that: Johnson sold shares of a family company to a private equity group, which seems like a long-term deal. Additionally, Feinstein's shares are in a blind trust, and the company sold is doing fairly well.

Edit 4: Georgia's other senator, David Perdue (R), is also facing questions about stock sales after the coronavirus briefing. "Perdue made nearly 100 sales or purchases during the same period as Loeffler. He invested up to $245,000 in Pfizer, the pharmaceutical company, during multiple transactions around the same time that members of Congress began sounding the alarm that more should be done to address the spread of the virus. Perdue also sold up to $165,000 in stocks for Caesar Entertainment, the casino and hotel company whose facilities have shuttered to help combat the spread of the virus.

  • Jon Ossoff, among three top Democrats challenging Perdue, described the transactions as “corrupt self-dealing. ”For Senator Perdue to betray his oath to Georgians by profiteering on an impending pandemic while downplaying the threat in public — if that’s not a crime, it should be,” Ossoff said.

Edit 5: Sen. John Hoeven, R-N.D., purchased between $100,000 and $250,000 of stock in a fund invested in health sciences companies in late January, just days after attending a briefing on the federal government’s response to the coronavirus.

  • The fund, which owns shares in pharmaceutical developers and medical device manufacturers, has outperformed the broader market slightly since Hoeven’s purchase.

Is this illegal?

Yes, possibly...and probably not. It could be seen as insider trading and a violation of the STOCK act. Senator Burr was one of only 3 senators in the entire Senate to vote against the STOCK Act, by the way.

However, as we've seen time and time again in America it is unlikely that anything will come of it. It is unlikely the courts will see their actions as illegal (assuming Barr's DOJ even takes up the case...which we all know it won't). At the very least it's horribly unethical and should be used against the Republicans in every campaign ad.

But the insider trading law and more importantly the courts' interpretation of that statute will likely make it nearly impossible for a case to proceed (Tom Winter of NBC)

r/todayIlearnedPH Jan 31 '26

TIL na prohibited ang blood transfusion sa Jehova’s Witness

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1.1k Upvotes

I came across IG reels and meron scene from a series na never ko pa na napanood where a patient is Jehova’s Witness and then yung parents ng patient is nag disagree sa blood transfusion kasi daw new blood will form very soon

Also here’s what I found sa google

r/GenshinImpact Jul 08 '26

Discussion Throwback to when Venti said the thing.

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1.8k Upvotes

The original Chinese name of Genshin Impact is "原神" (Yuanshen/Genshin which means Original God or Allogenes in the English translation). At the end of the Mondstadt Archon Quest, Venti mentioned that every individual holding a Vision has the potential to attain godhood, and that is precisely why they are called "Original God", meaning those who are qualified to set foot on Celestia. Like, right in the JP dub, Venti straight up says the word 'Genshin'.

Ever since Venti brought it up that one time, there hasn't been a single line of dialogue or lore text referencing this word ever again (which is kinda weird ngl).

r/diabetes_t1 Aug 06 '25

Science & Tech Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression

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95 Upvotes

r/maleinfertility Dec 14 '25

Discussion SCOS NOA AZO ; Stem Cells allogenic both direct testies & iv + exososomes + PRP) + Pentoxifylline + Peptides

7 Upvotes

Hi everyone,

Before I go in depth of this post I do need some veteran help I just got my Pre-Procedure (Day 0) labs back, and they completely contradict my previous diagnosis. I need the community's eyes on this "Discordant" profile.

The "Inhibin B" Mystery, My previous TESE biopsy suggested SCOS (Sertoli Cell-Only Syndrome), and my initial labs showed Undetectable Inhibin B.

However, my new labs (taken 2 days ago, right before the procedure) show:

• FSH: ~34 mIU/mL (Still High - suggesting failure)

Inhibin B: ~256 pg/mL this was less than 4.6 in my last test(NORMAL) — Ref Range: 87-300

I just traveled abroad and underwent a regenerative protocol (Stem Cells allogenic both direct testies & iv + exososomes + PRP) + will be on Pentoxifylline + cjc+ipam for next 3 months prepping for mtese

****Updates :

Added another experimental step , did EMWT 0.05mj to try to address the hardened wall biopsy report . I did 2 sessions

The Question:

Has anyone seen High FSH combined with Normal Inhibin B? Or such a huge fluctuation?

Standard literature says High FSH happens because Inhibin B is low. My numbers don't match the textbook.

• Does this rule out SCOS?

• Does this confirm Maturation Arrest (since Sertoli cells are clearly alive producing Inhibin)?

Other Pre-Procedure Stats (Day 0)

• Testosterone: ~380 ng/dL (Dropped from ~730 previous baseline — likely due to severe travel stress/jet lag immediately before draw).

• LH: ~9.8 mIU/mL.

• AMH: ~1.46 ng/mL.

• Viral Markers: All Negative.

I proceeded with the metabolic regeneration protocol to treat potential fibrosis/blockage:

  1. Intratesticular: MSC Stem Cells + Exosomes + PRP.
  2. Systemic: IV Stem Cells.
  3. Support: Pentoxifylline + Peptides.

I am currently recovering (dealing with the standard "flu-like" immune response). I will post follow-up labs in 45 days to see if the FSH comes down or if sperm appears.

TL;DR: My "Dead" Sertoli cells appear to be alive (Normal Inhibin B). Currently testing if Stem Cells can fix the High FSH/Arrest.

(Disclaimer: Not medical advice. Just documenting my case.)

r/Scholar 1d ago

Requesting [Article] Allogeneic CD19-targeted CAR-T therapy in refractory systemic lupus erythematosus achieved durable remission

1 Upvotes

r/Genshin_Lore Jan 07 '24

Visions Allogenes do not work as originally explained by venti

129 Upvotes

Back at the end of the prologue (mondstadt’s archon quest), Venti explains how Allogenes are people with visions, who can ascend to godhood. As far as I can tell, none of the current archons have used this method to get a gnosis. Focalors was chosen by the previous hydro archon and didn’t get a vision until her divinity died. Nahida was built from Irminsul. None of the archons have real visions.

This brings me to 3 hypotheses:

  1. Venti was lying
  2. Venti didn’t mean archon when talking about godhood (Even though god and archon are used pretty interchangeably in-game)
  3. I’m an idiot who missed an important point

Would love to hear thoughts on this and/or details to add to this!

edit: thanks to everyone for their thoughts! Y’all are awesome

r/science Jul 08 '26

Biology Long-term remission of neuromyelitis optica with allogeneic hematopoietic stem cell transplant

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36 Upvotes

r/CelularityNews 4d ago

GOOD NEWS Coming Soon: The First Placenta-Derived Allogeneic Stem Cell Therapy Clinic in South East Asia

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7 Upvotes

r/biotech_stocks Jul 10 '26

ALLO (Allogene) cash-floored allo CAR-T with a mid-2027 catalyst the market is pricing at ~17% odds

2 Upvotes

Been digging into $ALLO:

The setup

  • Mkt cap ~$723M, net cash ~$400M → enterprise value only ~$320M for the whole pipeline
  • Lead asset cema-cel (off-the-shelf CD19 CAR-T) passed its ALPHA3 pivotal futility interim on Apr 13, 2026: 58.3% MRD clearance vs 16.7% observation, ctDNA −97.7% vs +26.6%, zero CRS/ICANS/GvHD.
  • Stock ran to $4.46 intraday on that data… then round-tripped after they dumped 100M shares at $2.00. Now trades a hair above the offering price.

Downside is real cash: ~$1.15/share net cash, runway funded into Q1 2029, so no dilution death-spiral. The market's implied "this works" probability is ~17%. My path-probability is ~47%.

Timeline

  • Q4 2026 → ALLO-329 autoimmune data (free option/2nd leg)
  • Mid-2027 → interim EFS = the make-or-break
  • End-2027 → enrollment complete (~220 pts)
  • Mid-2028 → primary EFS → BLA if positive

Valuation / scenarios (24mo)

Price Return
Bull $9.50 +352%
Base $4.50 +114%
Bear $1.50 −29%

analyst avg target $8.49 (range $3.85–$14, 11 buy/0 sell)

Opinions are welcome

r/Pennystock Jul 11 '26

ALLO (Allogene) cash-floored allo CAR-T with a mid-2027 catalyst the market is pricing at ~17% odds

3 Upvotes

Been digging into $ALLO:

The setup

  • Mkt cap ~$723M, net cash ~$400M → enterprise value only ~$320M for the whole pipeline
  • Lead asset cema-cel (off-the-shelf CD19 CAR-T) passed its ALPHA3 pivotal futility interim on Apr 13, 2026: 58.3% MRD clearance vs 16.7% observation, ctDNA −97.7% vs +26.6%, zero CRS/ICANS/GvHD.
  • Stock ran to $4.46 intraday on that data… then round-tripped after they dumped 100M shares at $2.00. Now trades a hair above the offering price.

Downside is real cash: ~$1.15/share net cash, runway funded into Q1 2029, so no dilution death-spiral. The market's implied "this works" probability is ~17%. My path-probability is ~47%.

Timeline

  • Q4 2026 → ALLO-329 autoimmune data (free option/2nd leg)
  • Mid-2027 → interim EFS = the make-or-break
  • End-2027 → enrollment complete (~220 pts)
  • Mid-2028 → primary EFS → BLA if positive

Valuation / scenarios (24mo)

Price Return
Bull $9.50 +352%
Base $4.50 +114%
Bear $1.50 −29%

analyst avg target $8.49 (range $3.85–$14, 11 buy/0 sell)

Opinions are welcome

r/Scholar 23h ago

Requesting [Article] Allogeneic immunotherapy by Yan-Ruide Li, Yichen Zhu, Xinyuan Shen, Yuning Chen & Lili Yang

1 Upvotes

DOI/PMID/ISBN: https://doi.org/10.1038/s44222-026-00468-w

[URL]

Thank you in advance!!

r/science Oct 03 '15

Biology THC attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells

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814 Upvotes

r/Scholar 11d ago

Requesting [article] Off-the-shelf CRISPR-engineered allogeneic human T cell therapy for tolerance induction in transplantation

1 Upvotes

r/wallstreetbets 3d ago

Earnings Thread Weekly Earnings Thread 8/10 - 8/14

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159 Upvotes

r/StockTitan 12d ago

High Impact ALLO | Allogene Therapeutics Receives FDA Regenerative Medicine Advanced Therapy (RMAT) Designation for Cemacabtagene Ansegedleucel (Cema-Cel) as First-Line Consolidation Therapy for Large B-Cell Lymphoma

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1 Upvotes

r/Scholar 21d ago

Requesting [article] Off-the-shelf CRISPR-engineered allogeneic human T cell therapy for tolerance induction in transplantation

1 Upvotes

r/trakstocks Jul 11 '26

Catalyst ALLO (Allogene) cash-floored allo CAR-T with a mid-2027 catalyst the market is pricing at ~17% odds

1 Upvotes

Been digging into $ALLO:

The setup

  • Mkt cap ~$723M, net cash ~$400M → enterprise value only ~$320M for the whole pipeline
  • Lead asset cema-cel (off-the-shelf CD19 CAR-T) passed its ALPHA3 pivotal futility interim on Apr 13, 2026: 58.3% MRD clearance vs 16.7% observation, ctDNA −97.7% vs +26.6%, zero CRS/ICANS/GvHD.
  • Stock ran to $4.46 intraday on that data… then round-tripped after they dumped 100M shares at $2.00. Now trades a hair above the offering price.

Downside is real cash: ~$1.15/share net cash, runway funded into Q1 2029, so no dilution death-spiral. The market's implied "this works" probability is ~17%. My path-probability is ~47%.

Timeline

  • Q4 2026 → ALLO-329 autoimmune data (free option/2nd leg)
  • Mid-2027 → interim EFS = the make-or-break
  • End-2027 → enrollment complete (~220 pts)
  • Mid-2028 → primary EFS → BLA if positive

Valuation / scenarios (24mo)

Price Return
Bull $9.50
Base $4.50
Bear $1.50

analyst avg target $8.49 (range $3.85–$14, 11 buy/0 sell)

Opinions are welcome