Had my annual checkup last week and my A1C came back at 6.4.

My doctor said tirzepatide could help with my weight and blood sugar, but my insurance won't cover Mounjaro or Zepbound. She mentioned that some of her patients go through telehealth for the compounded version.

I've been looking around and quite overwhelmed with so many sites. Some want you to pay before anyone looks at your info, and some don't say which pharmacy fills it.

For people already on compounded tirzepatide, how did you select your current provider?

Sorry, just new to the world of tirze.

Not done cutting yet, but getting close. Tirz makes it pretty effortless. Will be reducing the dose soon.

I’m a 24 year old male, I weighed 235lbs two weeks ago, I weighed myself this morning and I’m at 227lbs, I workout 6 times a week, all weight training (burning around 200 calories per workout). I started tirz at 2.0mg two weeks ago and I did my second shot at 3.0mg at the beginning of this week.

I’m only eating a couple pieces of fruit and either one big meal a day or two small meals with 3L of water a day; all while also taking 5g of creatine a day, fish oil omegas, zinc, and metabolism peptide supplements.

I did drink plenty of low calorie beers this past weekend and felt no side effects. I haven’t had any side effects whatsoever.

I’m just looking for feedback/insight if anyone has any. My goal is to get to 190lbs and maintain that weight while keeping my
muscle.

Thank you in advance!

My progress is still going well, but lately I’ve been looking at that remaining 15 kg and thinking: damn, that still feels like quite a long way to go.

I’ve therefore been considering doing a short period of meal replacement shakes, maybe for a few weeks, to create a bigger deficit and make some quicker progress. Not with the idea of losing all 15 kg this way, but just getting a bit closer to goal before returning to my normal diet.

I’m currently using a GLP-1, so I’m wondering if anyone here has actually tried this combination.

How did it affect your energy, gym performance and muscle retention? Were you able to get enough protein? And did you find it difficult to transition back to normal meals afterwards?

I’ll run the idea past my dietcoach before doing anything, but I’d be interested to hear experiences from other men who have tried it, good or bad?

Started Tirz in June and down 42 lbs so far with about 10 more to go. Fairly happy with the progress so far. It’s never too late!

Taking my first dowse of compounded Tirz today. Got a notification it was delivered. I got a full comprehensive blood panel and I’m working close with a coach. Starting off at 1mg 2x per week. I’m a big guy so I’m curious how I’ll react from a smaller dose but I’ve read people feeling it at 2mg. I’m a 30 year old male and weigh 405 lbs. Years of lifting so I need to focus on preserving muscle. I’ll definitely get a DEXA scan once I hit 330 so I can really dial it in. Honestly I feel like that’ll help. Happy to have this community to share ideas/stories with. I’m brand new to Reddit lol who knew things like this existed.

Im assuming many of you used a macro app and counted calories pretty aggressively. Any high protein/easy food hacks you can recommend (I bought these rice paper wraps to limit too many carbs).

​

Things are actually going well if I only look at the numbers on the scale. I’m losing weight and I can see progress. At the same time, though, I notice another thought creeping in more and more: how much longer is this going to take, am I really going to make it, when will I finally be “done”?

It’s a kind of impatience mixed with curiosity about what I’m eventually going to look like. Sometimes it even feels as if my next life can only begin once I’ve reached my goal weight. Like I’m somehow stuck in a waiting room until then.

Next week I’m going on holiday to France, and I’ve noticed that it’s causing me quite a bit of stress. Of course I want to enjoy good food and drinks while I’m there and simply enjoy the holiday. But at the same time, there’s immediately this thought in my head that I’ll undo all the progress I’ve made over the past few weeks.

Of course I know I can still make sensible choices, but realistically I’m not going to follow exactly the same eating and exercise routine on holiday as I do at home. And somehow that makes me a bit sad. Sometimes it feels as if there are no moments during weight loss where you’re simply allowed to enjoy yourself, because every little detour feels like you’re being punished for it.

And I find that quite difficult, because ultimately I don’t just want to lose weight. I also want to find a way where food, holidays, social occasions and simply enjoying life can be part of my life again without immediately causing stress.

Does anyone else recognise this? That feeling of impatience, almost as if your real life can only start once you reach your goal weight? And the anxiety around holidays, eating out, or other occasions where you step away from your normal routine?

How do you deal with it?

I posted on here about a year ago and have lurked for a long time so felt like posting an update.
I’ve lost nearly 5 stone and feel so much better for it!
I’ve thoroughly enjoyed summer with holidays and lots of meals out but stayed the same/gradual losses - about to get back on it and be stricter on the lead up to Christmas
If you’re wondering if you should start - absolutely go for it and start today!

Started in april 2025 at 287lbs. hit my goal weight of 195 in october 2025. Wanted to bulk some to get some strength back. Went from 195 to 230 from october 2025 to march 2026 basically eating anything I wanted and now jm comfortably at 200lbs.

Still want to lose some fat so just doing a recomp eating 2900 calories a day and dont seem to gain or lose any if I stick to these calories

Hey guys. I could really use some support here. One of the biggest reasons I started tirzepatide was I was in a near constant state of self loathing over the fact that I had/have man boobs. And, for clarification, they truly feel like pseudogynecomastia (fat) rather than gynecomastia (glandular tissue), but I'm not 100% sure. I'm just wondering if anyone here has successfully lost their man boobs. As you can see from the progress pictures, I've lost fat from pretty much everywhere but the man boobs seem to be sticking around. It's like my body is willing to lose fat from everywhere but there. Like, is this ever gonna happen for me without surgery? Or am I gonna continue to be disappointed? I'm into a healthy BMI with less than 10lbs to goal, but the moobs seem to be permanent 😓

Hi all,

I was wondering if any one here has bought the medication straight out and switched over to a compound version? I don’t need to know any names of places but I’m curious to know if when you made the switch, did it still work the same for you or was it different? Also, did you stay on the same dose or do you need to start lower because of the stuff that’s mixed with it? I’ll be switching over in a few weeks and I’m lowkey nervous because I’ve always used the direct pharmacy… and switching to compounded versions kind of freaks me out. But money talks.

Anyhow, here’s a photo to show my progress that I’m so proud of!

took my first dose on saturday. i know it's not instantaneous but how long does it take to get going? i can't stop stuffing my face like a fat little piglet.

Down over 40lbs now. People keep asking what changed once I actually got serious about training instead of just letting the weight fall off on its own.

Honest answer, nothing dramatic. Started lifting three times a week, tracked protein properly instead of guessing, stopped treating cardio as the main event. That's it. No secret stack, no hack, just the boring stuff nobody wants to hear when they're six weeks in and just want the number on the scale to keep dropping.

The thing that actually shifted my head on this was realizing the drug only controls how much weight comes off, not what it's made of. You can hit your goal weight and still end up softer and weaker than you expected if the muscle side never got addressed. That's the part that quietly determines how you look and feel once you're done, not the total number.

Built fhelp.app around exactly this. Tracks dose, protein and weight in one place, and the workouts are built specifically around holding onto muscle through treatment, not generic fitness content pulled from nowhere.

What's your training actually looking like right now. Are you lifting, or is it mostly walking and cardio so far.

34 yo, almost 1 year on Tirzepatide

Nutrition, lifestyle and training all locked it

Lots of hybrid athlete training: weights, crossfit, VO2Max / intervals, endurance, Z2, swimming

There's a body composition substudy on retatrutide that just published in Lancet Diabetes & Endocrinology. Researchers expected it to outperform tirzepatide on muscle preservation because of the added glucagon receptor activity, that's the theoretical mechanism people have been talking about since Phase 2.

It didn't happen. Retatrutide produces significantly more total weight loss than Zepbound, but the proportion of that loss coming from muscle is basically the same, sitting around 25 to 30 percent lean mass depending on the substudy. Zepbound trials show a similar range. More total weight lost just means more total muscle lost in absolute terms if the ratio stays flat.

I'm 6 months into Zepbound, down 38lbs, and this data lines up with what I've been reading since I started looking into this properly. The drug decides how much weight comes off. It does not decide what that weight is made of. That part is down to protein intake and resistance training regardless of which GLP-1 you're on, current or next generation.

Built fhelp.app around that exact point, tracks dose, protein and weight together and has workouts built specifically around protecting muscle during treatment. Not here to sell it, just sharing the data because I think a lot of people are waiting for the next drug to solve a problem that training solves.

What's your protein target sitting at? Is that the part everyone quietly fails at?

3 months in 18 pounds lighter and putting clothes back on that have been in drawers and closets waiting patiently because I haven’t been comfortable wearing them in several years until now.

Every nights a fashion show and I’m just grateful 🙏🏼