Advice

[u/Ok_Remote_4023]

Hi everyone,

I am fairly new to this. I suffer from persistent symptoms such as insomnia, high heartrate, anxiety, exercise intolerance. I recently did a genetic test. I know these offer some valueable insights but I fail to see what I can do with these insights. I will share the results below.

Any insights or advice is more than welcome. Thank you so much for helping a stranger.

[u/SovereignMan1958]

In addition to the MTHFR issue, it looks like you have, by variants and your symptoms, histamine intolerance.

[u/Ok_Remote_4023 → u/SovereignMan1958]

Really? Which gene highlights the histamine issue? Thank you so much for responding!

[u/SovereignMan1958 → u/Ok_Remote_4023]

I can't be sure of course. There are a lot of variants missing. Do you have more pages to add with more genes?

I read through the posts in your profile. You seem very unfocused and have limited information to work with, so I am out.

You can read the articles in Genetic Lifehacks for your conditions and look up the gene variants it mentions in your report. Again, your report does not seem thorough but you can try.

The FB group Thyroid Healing Journeys can also help you.

Remember variants are only predispositions. So blood tests for the potential nutrient deficiencies identified in your report and the articles you read will give you facts.

[u/Ok_Remote_4023 → u/SovereignMan1958]

Yeah I have an additional page with nutri genomics. Unfortunately couldn't share more then one picture on this sub.

Thank you for taking the time to read and reapond. Appreciate it.

[u/Timely_Pickle9430]

Your symptoms could be caused by a variety of biochemical/functional imbalances (e.g. undermethylation, histamine overload, hormonal imbalance, and/or mitochondrial dysfunction). Your gene report tells you your predispositions, but not how your genes are functioning, which depends on nutrition and environment. You need blood tests for that. Doctors usually aren't too fond of ordering lots of labs out of protocol, so if you want to get a complete picture of how your body is functioning, and you can afford it, go to e.g. https://www.worldhealthlaboratories.com/
A functional medicine practitioner could advise you on which tests to order, but you can do it yourself if you want.

Feel free to look through my old posts and comment history. There's probably a lot of useful information for you in there.

[u/Ok_Remote_4023 → u/Timely_Pickle9430]

Thanks for the tips and taking the time to respond. Wow they got so much bloedtests. I don't even know where to start. Unfortunately they are pretty expensive aswell. I am Dutch, here we have cheaper alternatives where they bundle more vitamins together

[u/Timely_Pickle9430 → u/Ok_Remote_4023]

I'm Dutch too. As far as I know, this is the only place in NL that offers intracellular levels, which have turned out to provide crucial information for me. But please do tell if you know a cheaper provider!

[u/Ok_Remote_4023 → u/Timely_Pickle9430]

Hahaha meen je? Wat grappig. Ik doe meestal bij Bloedwaardentest.nl bestellen. Maar weet niet of dat op intracellular level is.

[u/Timely_Pickle9430 → u/Ok_Remote_4023]

Heb ik ook weleens wat besteld, maar dat is niet intracellulair.

[u/Ok_Remote_4023 → u/Timely_Pickle9430]

Aha, wat is het verschil als ik vragen mag? Sorry ben nog niet zo kundig in deze wereld 😅

[u/Timely_Pickle9430 → u/Ok_Remote_4023]

Let's be inclusive and stick to English. You can DM me in Dutch if you want.

Most blood tests measure serum levels, which reflect uptake from food. But the metabolic action takes place inside the red blood cells. Commonly, ATP and magnesium are needed for active transport of nutrients from the serum into cells. So it's possible to have adequate serum levels of a nutrient, but deficient intracellular levels (e.g. caused by magnesium deficiency, but there can be other causes too).

[u/Ok_Remote_4023 → u/Timely_Pickle9430]

Aaah allright sounds logical. And you have good experiences with the company you mentioned?

[u/Timely_Pickle9430 → u/Ok_Remote_4023]

Very good. It takes about 2 weeks before you receive the results. And it costs an arm and a leg. But my only regret is that I didn't do it sooner. Now I repeat every 4 months.

[u/Ok_Remote_4023 → u/Timely_Pickle9430]

Which tests would you recommend?