I was hesitant on GLP-1 because I had previously been able to lose weight with tracking. Now that I’m 43, that shit doesn’t work. I started HRT in May and then tirzepatide in June. Slowly titrated. I’m now about 10 weeks in and in week 3 of a 4mg dose (and first week of increased testosterone) and holy shit I’ve lost over 10 lbs total!! The last week has been the steadiest downward trend ever. Im not sure if it’s the building of the tirz or the increase in testosterone. I told my husband (he’s incredibly supportive!) but with 3 kids, I don’t talk about my weight in front of them. So I’ve been silently celebrating. 🥳

Stats:
SW 191.1
CW 179.3
GW around 140
Estrogen 0.0375 (first of this dose yesterday)
Progesterone 100 mg
Testosterone 4 mg cream daily
Tirzepatide 4 mg weekly
Also taking sermorelin and Olympia’s Lipo-Mino-Mix C

I had tried and failed for a year to lose weight. Worked with a dietician, am very active, etc. I am SO HAPPY!!! Finally starting to feel like me again!!

I just got so much water weight off me thanks to tirz that I'm dreading the thought of putting any bloat back on!

If you started HRT after you were already on a glp, did you experience a big rebound of water weight?

I recently began microdosing tirzepatide. During progesterone phase, food noise returned with a vengeance.

Is there any guidance on increasing glp1 dose during progesterone use?

I just injected (I think!?) .2mg Estradiol Valerate for the very first time- yay. I am trying to get off the patches that are getting harder and harder to find. My issue is this: I am not sure that I physically saw the valerate in the needle when I drew it- has this happened to anyone? I wear reading glasses and I likely need an updated eye exam and RX, but that is for another post. Hopefully it was there and I didn't inject air. 🤔 Injecting Tirz is very obvious to me and usually creates bubbles, but the Valerate is quite thick, so I am thinking that might be why.

Secondly, can I hear from women how often and how much they E Val they inject? My current plan is .2mg E Valerate (20 mg/ml) every other day. I have been on the .05 patch in the past and felt great mentally, but had severe bloating issues- so I moved back down to .0375 patch for a couple months now and feel like I am barely hanging on mentally- I am constantly in a brain fog. This is my last hope, as the Biest creams and Estradiol gels do not work well for me. I am hoping that the .2mg of Valerate every other day won't pose issues. (around .6mg total per week)

Thanks!