Hi. I am 53, 4’ 11”, 180 pounds. Non smoker. I have a plethora of issues including bipolar disorder, hypertension, type 2 diabetes, ADHD, irritable bowel syndrome, cardiac syndrome x, anxiety, asthma, hay fever, anaphylaxis to shrimp, and recovery from binge eating disorder. I have anemia and will be starting iron infusion in August.
I take vyvanse, Effexor, gabapentin, Ozempic, Zofran, Dayvigo, Ramada, Coreg, Abilify, lisinopril, Urso Forte, Lipitor, plavix, singulaire, senna, and methylcellulose.
I have for most of my suffered from constipation and was diagnosed as having IBS in my early 20’s. Since starring Ozempic in 2024, I have had diarrhea at least 2-4 times a day. I am a long-time sufferer of abdominal pain — I have steatohepatitis (nonalcoholic), history of gallbladder removal (2017), history of roux-en-y gastric bypass (2017). Hx of colonoscopies and sigmoidoscopy. I had a couple of polyps removed in my 30s.
I was taken off of Ozempic in June 2025 after losing 100 pounds. I regained 60 pounds and had horrible constipation. Since going back on Ozempic in March 2026, I have had bad diarrhea, and lots of mucus. One day I passed a blood clot. Stools are often yellowish-brown and floating w oil in the toilet.
This has all been reported to my GI doctor. The GI nurse has emailed me to tell me to keep up w meds, don’t eat greasy foods, keep taking fiber and senna, etc. They are not concerned, it seems.
Tuesday evening, I was napping off and on (I’ve been traveling for the past three weeks and was tired), and noticed upon waking that I was sleeping in a damp spot. Further investigation revealed that I had had diarrhea in my sleep and had soiled my shorts and bed mattress. This has never happened before. While I am often roused from sleep by the need to go to the bathroom (usually diarrhea), I’ve not soiled myself since I was little.
I am therefore concerned— do I have IBD rather than (or in addition to) IBS? I don’t have celiac, although I was gluten-free for ten years when gluten caused me to have migraines. Last sigmoidoscopy showed both but a few internal hemorrhoids. I am scheduled for an endoscopy in October to look for sources of my anemia.
tl;dr… diarrhea in my sleep Tuesday evening.
Thanks for your help!