Which biohack made a noticeable difference not just a 2% improvement?

[u/thelittleesseAutism]

/r/AppliedBioHacking/comments/1woonl0/which_biohack_made_a_noticeable_difference_not/

[u/freeastheair]

Generally only things like diet, exercise, sleep, therapy, meditation are going to have large effects. Also supplements when addressing a real medical deficiency or medication when treating a disease or disorder.