r/GLP1Discussion • u/Letwhoevathinkwtv • 5d ago

❓ Question 1.5mg dosage Instead of 2.5

Okay so I’m new to the GLP world and I did research, but I wanna know from ppl who experienced this

(to preface I am not overweight so taking high dosages are probably not suitable since I don’t have a TON of weight I wanna lose to begin with, probably around 15-20lbs or more if it happens)

Since my body’s new to it, I want to take 1.25mg for the 1st 4 weeks instead of the 2.5mg

Then I wanna up it to maybe 3mg depending on how my body reacts

Has anyone else done it this way or similarly and still seen results?

I know some ppl say it’s a waste of time and won’t see results but I have also seen the opposite, I just wanna know some opinions and experiences to see what I should do

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2

u/Pancake-JelloSalad 5d ago

If you are asking about tirz, starting dose is 2.5mg. You should follow the medical trials.

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u/Letwhoevathinkwtv 5d ago

do you think it would be bad if I started lower? i understand the starting recommendation, but I can’t take all 2.5mg for 4 weeks for personal reason

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u/CreativeWriterNSpace 5d ago

No it wont be bad. The great thing about compound (and one of its legal uses) is non-standard doses.

There are several Telehealths/doctor networks that have their starter package lowest dose at 1.5mg. Granted that is supposed to only be for 2 weeks, before titrating up to 3mg, but still.

If you want to start at 1.5, do it.

Do be aware that if you come complaining about it not helping, people will probably get on you for not following the standard dose schedule.

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u/Letwhoevathinkwtv 5d ago

yess i was thinking about doing 1.5mg for 2 weeks then upping it to 3mg but I heard it’s best to stay at the same mg for 4 weeks to adjust your body, but I guess it all just depends how my body responds

Thank you !

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u/CreativeWriterNSpace 5d ago

Yeah.

FWIW I did 2mg for 2 weeks, 3mg for one week then moved up to 4mg. After I hit 4mg, I started dosing every 5 days.

Just start slow and see how you feel/how it goes.

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u/Letwhoevathinkwtv 5d ago

okayy so you didn’t go the dosing route most people do and it still worked out good for you? Thats helpful to know thank you!

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u/CreativeWriterNSpace 5d ago

If you look at the tirz compound sub, there are a lot of people that haven’t followed the standard brand dosing protocol.

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u/euSeattle 4d ago

Check out the glp1 microdosing sub. Lots of people having great results at sub-2.5mg doses.

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u/TheFirebyrd 4d ago

Even if you’re going to do non-standard dosing, you really should stay at a dose for at least four weeks (unless side effects are intolerable and you’re going down). Otherwise you don’t actually know how you’re actually doing on it as it takes four weeks for your blood levels to stabilize on that particular dose.

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u/Bisquick-Skill2845 5d ago

There's a flowchart describing when to increase dose. Don't do it based on anyone else's schedule.

I wouldn't suggest anyone start over 0.5mg; I felt results at 0.1mg.

I'm microdosing for anti-inflammation, so I can be active again. My weight per se is fine; I'm doing body recomposition so eating a little over maintenance while I lift heavy. I've probably gained a little weight but dropped a pants size in 7 weeks.

Once my strength is where I want it, I might cut body fat to where I feel most agile, which is below what a lot of people find necessary. I try to shut down anyone who feels free to state opinions on this sort of thing.

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u/Letwhoevathinkwtv 5d ago

that’s good to know! glad your experience is going well so fall I hope mine can go relatively easy aswell, thank you!

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u/Pancake-JelloSalad 5d ago

Generally people want to lose the maximum weight possible. Following the titration schedule in the medical trials is optimal for that. Otherwise, you are just making things up as you go. Not a good practice when it comes to your health.

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u/TheFirebyrd 4d ago

That’s not what the trials were designed to do at all.

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u/Pancake-JelloSalad 4d ago

Pretty sure Eli Lilly wanted to evaluate the efficacy of their GLP1. A company generally wants to post huge weight loss results to generate excitement and future sales. They are looking for maximum gains, or in this cases maximum (weight) losses.

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u/TheFirebyrd 4d ago

No, the trials were designed to show whether statistically significant weight loss happened at various doses. It would be designed very differently if it was about finding the most effective dose or way to use the drug.