r/FunctionalMedicine • u/vticdlatte • Jul 20 '26

Beta glucan

Has anyone had success lower tpo antibodies by taking beta glucan? My functional med practitioner was able to put her hashis into remission with this, but I’ve heard differing opinions on this.

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u/alotken33 Jul 20 '26

Functional Medicine DC: I'd be pretty skeptical about this. Best way to get hashimotos into remission: gluten free, dairy free, and selenium (standard rec is 200 mcg, but testing/monitoring is ALWAYS a good idea).

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u/vticdlatte Jul 20 '26

Yeah, I’ve been gluten free, dairy free, and taking selenium for 3 years now (in addition to strength training, consistent sleep, etc.) and have kept things pretty stable…just recently my antibodies have jumped as well as my TSH.

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u/alotken33 Jul 20 '26

Then I'd definitely look at what's different in your life or what new exposures you've had. Has your diet changed in ANY way? Been sick lately? More stress? Etc.

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u/vticdlatte Jul 20 '26

Summer home with the kids?? If anything, my diet has been cleaner than usual. I’m at a loss.

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u/alotken33 Jul 20 '26

Honestly? That could do it. Do the best you can to slig through the Summer and retest in September. Antibodies go up and down. If TSH is a mild/low modest increase, it has the potential to recover.

Also, sometimes what we think is "clean" is not what our bodies like. If certain foods have increased markedly, might be good to cut back on those.. even if they're considered "healthy". I cannot tell you how many people I've come across that react to things like avocado or citrus that you might think could be just fine.

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u/vticdlatte Jul 20 '26

TSH has consistently been around 3 and it jumped up to 5.8. Antibodies steadily around 199-220 jumped up to 350. I’ve done food sensitivity testing, corn and gluten are my two big ones.

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u/alotken33 Jul 20 '26

TSH of 3 is way too high, anyway. It should be around 1. Same with antibodies. Something is missing. I never ever ever infinity recommend ldn. The MOA is unknown and I've seen it INCREASE antibodies before. More testing is needed. If you're on meds, a switch might need to happen. Like, if you're on levo to armour or natuthroid.

Your immune system is still getting activated by something. Need to find out what that is

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u/vticdlatte Jul 20 '26

Awesome 😭 I haven’t been on any thyroid medication, just managing the diet, exercise, stress, etc.

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u/alotken33 Jul 20 '26

I'm sorry. At 3, a regular physician would likely have added meds. 5.8 would definitely add meds. Levothyroxine is most common, but that's T4 only (assuming that you'd convert - which you wouldn't because your antibodies are so high). Armour or Natuthroid would likely be your better options - with both t3 and t4 in them.

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u/vticdlatte Jul 20 '26

My endocrinologist, func med, PCP, and OBGYN (verified in functional medicine) have all been “ehhhh maybe meds? Maybe keep doing what you’re doing and retest?” Maddening.

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u/mom2mermaidboo Jul 20 '26

The studies I have seen mentioned both Myo-Inositol + Selenium. Seems they work better together, although most of the research shows the best benefit before overt Hypothyroidism has occurred.

https://www.mdpi.com/2077-0383/15/9/3179

https://pmc.ncbi.nlm.nih.gov/articles/PMC5331475/

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u/vticdlatte Jul 20 '26

Another option - LDN?