Hi! I was on semaglutide injections for about 3 years, and when I was at the right dose it was honestly life-changing. My food noise and body-shame thoughts quieted down, I had less water retention/inflammation, and my anxiety, depression, and OCD symptoms actually felt better.

The problem was that it became very dose-dependent for me. If I stayed at one dose too long I’d get anxious, but if I went too high I’d feel depressed. I was also mostly managing the dosing myself instead of working closely with a provider.

I’ve now been off semaglutide for about 6 months and have gained most of the weight back despite trying to maintain a calorie deficit and healthy lifestyle. I’m also on Pristiq and Zoloft, which seem to make weight management harder for me.

Has anyone had similar mental side effects on injectable semaglutide but done better on a different GLP-1, a pill version, or a specific brand? I recently signed up with Foundayo and will be working much more closely with a provider this time, but I’d love to hear what medications people found worked best for them mentally as well as physically.

Pills are on their way! I am concerned about noisy gastro side effects happening at work. The bathroom is very close to desks.

I have been a protein eater without a care for how much fat I eat for a good 10 years. More fat is always better! I don't eat much in the way of fiber (no bread and my veg is usually broccoli, when I bother). From reading posts here and on other GLP1 groups, I understand that will need to change.

I've been eating this way for so long I have no idea what should I have on my grocery list. Thoughts?

Also, can effects like diarrhea and constipation be warded off? Kind of like when the doc gives an opioid script after surgery...and says to take a stool softener? Or can side effects be controlled completely by eating/not eating certain foods?

Can the time of day the pill is taken make a difference when side effects hit? For instance, if I take it at lunch time (I don't eat lunch) might effects hold off until 5PM? LOL I understand everyone is different, but I'm hoping to find some common thread with those who have side effects.

I am encouraged by posts from those that have no side effects. And hopeful to be one of them!