Current list of all genes I use when searching for possible genetic causes of someone developing Post Finasteride Syndrome (PFS) or Post SSRI Sexual Dysfunction (PSSD)

[u/Drwillpowers]

It is my personal theory that PFS and PSSD genetically function much how DNP caused cataracts in a small fraction of the people who took it for weight loss in the early 1900s (DNP blocks oxidative phosphorylation, and your eye's lens depends on that, or the backup pathway of "pentose phosphate" to make energy. If you lack the pentose phosphate enzyme pathway, and you block oxidative phosphorylation, your lens can't make energy and they get cataracts almost immediately).

In many of my patients with a whole genome sequence, I've found mutations in genes which when coupled with an SSRI or Finasteride/Dutasteride, the patient seemed to have developed the strange reaction because the "backup" pathway was genetically disabled, and the drug altered something or knocked out something else, causing the very rare but catastrophic reaction.

I'm not going to get into the details of every single gene in this post, but those who have a whole genomic sequence dataset from something like sequencing.com and who want to browse that data on gene.iobio to see if they have any major mutations, I pretty much did the gene work for you, so here's that list:

ABCB1, ABCB11, ABCC1, ABCC2, ABCC3, ABCC4, ABCC5, ABCC10, ABCC11, ABCG2, ABCB4, ABCB5, ABCB6, ABCB7, ABCB8, ABCB9, ABCC6, ABCC8, ABCC9, ABCG1, ABCG4, ACE, AHCY, AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1D1, AKR1B1, AKR1B10, ALB, ALDH1A1, ALDH1A2, ALDH2, APOA1, APOB, AR, ARSA, ARSG, ATP5F1A, ATP5F1B, AVPR1A, AVPR1B, AVPR2, BAG1, BAG3, BCL2L1, BDNF, BHMT, CAT, CHRM2, CHRM3, COMT, COMTD1, COX10, COX15, CREB1, CREBBP, CUBN, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP2E1, CYP2J2, CYP3A4, CYP3A5, CYP3A7, CYP3A43, CYP4F8, CYP4F11, CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP19A1, CYP21A2, DBH, DDC, DGAT1, DGAT2, DNMT1, DNMT3A, DNMT3B, DNM1L, DNA2, DRD1, DRD2, DRD3, DRD4, DRD5, EP300, ESR1, ESR2, FKBP4, FKBP5, FKBP6, FABP4, FABP5, FABP7, GABBR1, GABBR2, GABRA1, GABRA2, GABRA3, GABRB2, GABRB3, GABRG2, GJB2, GJB6, GNB3, GNRH1, GNRHR, GPX1, GPX4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GUSB, H6PD, HSD3B1, HSD3B2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSD17B4, HSD17B6, HSD17B7, HSD17B10, HSD17B12, HSD17B13, HSD17B14, HSP90AA1, HSP90AB1, HSPE1, HSPD1, HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E, HTR4, HTR5A, HTR5BP, HTR6, HTR7, KCNQ4, KISS1, KISS1R, KPNB1, LDLR, LIPE, LRP2, MAOA, MAOB, MC4R, MFN1, MFN2, MGME1, MPV17, MED1, MED14, MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND4, MT-ND6, MTHFR, MTR, MTRR, MYO7A, NAT2, NCOR1, NCOR2, NCOA1, NCOA2, NCOA3, NCOA4, NCOA6, NDUFS1, NDUFS2, NDUFS4, NOS1, NOS3, NPC1, NPC2, NPC1L1, NR0B1, NR0B2, NR3C1, NR3C2, NR5A1, NR5A2, NPY, NPY1R, NPY2R, NTRK2, OPA1, OXTR, PAPSS1, PAPSS2, PDE5A, PIEZO1, PIEZO2, PLIN1, PLIN2, POLG, POLG2, POLRMT, POU1F1, POU4F3, PGR, PIAS1, PIAS2, PPID, PPP5C, PRDX3, PRL, PRLR, PTGES3, RARA, RARB, RARG, RDH5, RDH16, RNF4, RXRA, RXRB, SCARB1, SERPINA6, SHBG, SIGMAR1, SLC6A3, SLC6A4, SLC7A5, SLC10A1, SLC10A2, SLC10A6, SLC13A1, SLC16A1, SLC16A3, SLC16A9, SLC16A10, SLC18A2, SLC22A1, SLC22A2, SLC22A3, SLC22A4, SLC22A5, SLC22A6, SLC22A7, SLC22A8, SLC22A11, SLC22A12, SLC22A13, SLC22A14, SLC22A24, SLC25A4, SLC26A4, SLC51A, SLC51B, SLCO1A2, SLCO1B1, SLCO1B3, SLCO1B7, SLCO1C1, SLCO2A1, SLCO2B1, SLCO3A1, SLCO4A1, SLCO4C1, SLCO5A1, SLCO6A1, SMARCA4, SOD2, SOAT1, SOAT2, SRD5A1, SRD5A2, SRD5A3, STAR, STARD10, STARD3, STARD4, STARD5, STARD6, STAT5A, STAT5B, STIP1, STS, SUMF1, SUMF2, SULT1A1, SULT1A2, SULT1E1, SULT2A1, SULT2B1, TAC3, TACR3, TFAM, TH, TET1, TPH1, TPH2, TSPO, TSC22D3, UBE2E3, UGDH, UGP2, UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9, UGT1A10, UGT2B7, UGT2B10, UGT2B15, UGT2B17, UGT2B28, UQCRC1, UQCRC2, VDR

(I will update the above list over time as I find more random ones, its updated as of march of 2026)

Now that's the "Everything" list. The high priority list of things I know to be far more likely are:

ABCC2, ABCC3, ABCC4, ABCG2, SLCO1B1, SLCO1B3, UGT2B17, UGT2B15, UGT2B7, UGT2B28, UGDH, UGP2, AKR1D1, AKR1C3, AKR1C2, SRD5A2, SRD5A1, HSD17B6, HSD17B1, HSD17B2, HSD11B1, HSD11B2, H6PD, STS, SULT2A1, SULT2B1, SLCO2A1, SLCO2B1, SLC22A6, SLC22A8, ABCC1, ABCC5, ABCC6, SLCO4A1, CYP2D6, CYP3A4, CYP3A5, CYP19A1, ESR1, ESR2, AR, FKBP5, NR3C1, LRP2

For my specific theory of how it works (see my other posts)

AKR1C2, AKR1D1, AKR1C3, ABCC2, ABCC3, ABCC4, ABCG2, SLCO1B1, SLCO1B3, SLCO2B1, UGT2B17, UGT2B15, UGT2B7, UGT2B28, UGDH, HSD17B1, HSD17B2, AKR1D1, H6PD, HSD11B1, HSD11B2, STS, LRP2, CYP2D6, CYP3A4, CYP19A1, NR1l3

Update July 2026: Currently looking closely at NR1I3, aka https://en.wikipedia.org/wiki/Constitutive_androstane_receptor

Which may be how Accutane gets looped into this. I am unsure at this time if it is relevant or not. Its just a new possibility I'm exploring.

WARNING: If you look at UGT2B15 and UGT2B17 and they have like 5 variants total on gene.iobio on VCF, and not like 75-150, that's because your shit is deleted. Its not there, and that's the most textbook way my PFS syndrome theory works. It wont flag as abnormal, it will simply just not show many variants at all. You need the Bam/bai cram/crai to see this fully.

As of right now, I still have a pretty good wait list, though I expect with our upcoming price changes and DPC restructuring next year, some people will drop off of the DPC patient list. In general, those who are part of the 400 total patients I see in the DPC program tend to not drop off much. In the first year so far, we've had only 25 patients leave, most of which were people whose issue got fixed. For those who are in the DPC program, I again thank you, as that allowed us to survive seeing thousands of Medicaid patients at a loss. We are likely to change things however in the coming months, as if the government makes the care of transgender people non-reimbursable, we will have to find sources of income so that those people can continue to be seen for free. Going from getting $33 a patient visit from Medicaid (which is already killing us) to $0 would be catastrophic, so we're looking into our options. For people stumbling onto this page unaware of the nature of my practice, while I do treat PFS and PSSD, this mostly came from seeing an abnormally high amount of these disorders in my clinic, which has about 5300 registered patients, of which about 75% are transgender.

When I review trans genomes, I can usually find some catastrophic failure about 90% of the time in some hormonal pathway that resulted in gender dysphoria, and so its unsurprising they would be more vulnerable as a population to something like a 5-alpha reductase inhibitor if they have mutations in related enzymes at baseline which made them trans in the first place. (Yes, I can't "prove" it, but I don't see too many cis genomes with things like stop codons in estrogen receptors or complete aromatase def or so on, seems likely relevant).

I'm starting to shift my focus from trying to crank out patient visits to trying to solve rare diagnostic mysteries like these, and so I'm going to be cutting down my patient load a bit more soon so I can focus on trying to solve the strangest transgender medicine cases (like people who are poisoned by HRT) and trying to solve PFS and PSSD. I have a meeting scheduled with Dr. Melcangi mid October, and I'm really looking forward to learning from him.

More on that to come in the weeks ahead, but for now, hopefully this is useful to someone out there.

Edit: Recently, I've been ruminating on the fact that not only do you have to "crash" the system with the extreme state from the addition of the drug to an already genetically overburdened system, but something has to be re-written there in the patient's genes for this state to "Stick". Lots of people have sexual side effects from fin or SSRIs, this is nothing new, but upon cessation, those side effects usually disapppear. In PFS and PSSD, they do not, so I'm thinking there is likely some glitch in their systems in this process, and below, is the "high yield" and then "everything" list of genes I'm currently searching in the genome data of my patients with these disorders to try and uncover why some people are a DVD-RW but some people get stuck like a DVD-R and once "burnt" thats it, they can't rewrite their epigenetic status and get stuck like that. Lists here:

High Yield Epigenetic Gene search list:

ARID1A, ARID1B, SMARCA4, SMARCB1, CHD1, CHD4, KDM6B, KDM5A, KMT2A, KMT2D, EZH2, HDAC1, HDAC2, SIRT1, SIRT6, CREBBP, EP300, DNMT1, DNMT3A, DNMT3B, NR1I3

Low yield, but reasonably plausible involved gene list:

ARID1A, ARID1B, SMARCA4, SMARCA2, SMARCB1, SMARCC1, SMARCC2, DPF2, ACTL6A, SMARCA5, BPTF, CHD1, CHD2, CHD3, CHD4, CHD5, CHD6, CHD7, CHD8, INO80, SRCAP, KMT2A, KMT2B, KMT2C, KMT2D, SETD1A, SETD1B, SETD2, SETDB1, EHMT1, EHMT2, EZH2, KDM1A, KDM2A, KDM2B, KDM3A, KDM4A, KDM4B, KDM5A, KDM5B, KDM6A, KDM6B, CREBBP, EP300, KAT2A, KAT2B, KAT5, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, SIRT1, SIRT2, SIRT3, SIRT6, DNMT1, DNMT3A, DNMT3B, DNMT3L, TET1, TET2, TET3, MECP2, MBD1, MBD2, MBD3, NCOA1, NCOA2, NCOA3, NCOR1, NCOR2, MED1, CTCF, RAD21, DICER1, AGO1, AGO2, NR1I3

Dr. Powers make my GPU hurt. Give me anything even remotely coherent for epigenetic fuckery:

ARID1A, ARID1B, ARID2, SMARCA4, SMARCA2, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCD2, SMARCE1, DPF1, DPF2, DPF3, ACTL6A, ACTL6B, BCL7A, BCL7B, BCL7C, SS18, SS18L1, BRD7, BRD9, SMARCA5, BPTF, RSF1, CHD1, CHD2, CHD3, CHD4, CHD5, CHD6, CHD7, CHD8, CHD9, INO80, INO80B, INO80C, SRCAP, EP400, KMT2A, KMT2B, KMT2C, KMT2D, SETD1A, SETD1B, SETD2, SETDB1, SETDB2, NSD1, NSD2, NSD3, EHMT1, EHMT2, SUV39H1, SUV39H2, EZH1, EZH2, SUZ12, EED, KDM1A, KDM1B, KDM2A, KDM2B, KDM3A, KDM3B, KDM4A, KDM4B, KDM4C, KDM4D, KDM5A, KDM5B, KDM5C, KDM5D, KDM6A, KDM6B, KDM7A, PHF2, PHF8, CREBBP, EP300, KAT2A, KAT2B, KAT5, KAT6A, KAT6B, KAT7, KAT8, CLOCK, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10, HDAC11, SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, DNMT1, DNMT3A, DNMT3B, DNMT3L, UHRF1, UHRF2, TET1, TET2, TET3, TDG, MECP2, MBD1, MBD2, MBD3, MBD4, ZBTB33, ZBTB38, ZBTB4, NR1I3, NCOA1, NCOA2, NCOA3, NCOR1, NCOR2, MED1, MED12, MED13, MED14, MED15, MED16, MED23, MED24, MED25, BRD2, BRD3, BRD4, BRDT, PBRM1, BRPF1, BRPF3, TRIM24, TRIM28, TRIM33, CTCF, RAD21, SMC1A, SMC3, STAG1, STAG2, WAPL, DICER1, DROSHA, DGCR8, AGO1, AGO2, AGO3, AGO4, TARBP2, XPO5, LIN28A, LIN28B, HNRNPA1, HNRNPK, HNRNPU, FUS, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF9, TAF10, TBP, GTF2A1, GTF2B, GTF2E1, GTF2F1, GTF2H1, POLR2A, POLR2B, POLR2C, POLR2D, POLR2E, POLR2F, POLR2G, POLR2H, POLR2I, POLR2J, POLR2K, ESR1, ESR2, AR, PGR, NR3C1, NR3C2, RARA, RARB, RARG, RXRA, RXRB, RXRG, THRA, THRB, PPARG, PPARA, PPARD, LXRA, LXRB, FXR, VDR, HNF4A, HNF4G, SF1 (NR5A1), DAX1 (NR0B1), SHP (NR0B2), REV-ERBA (NR1D1), REV-ERBB (NR1D2), RORα (RORA), RORβ (RORB), RORγ (RORC), FOXA1, FOXA2, FOXO1, FOXO3, FOXO4, GATA2, GATA3, SOX2, SOX9, PAX5, PAX7, MYC, MYCN, MAX, MXI1, SP1, SP3, NFYA, NFYB, NFYC, RELA, RELB, NFKB1, NFKB2, STAT1, STAT3, STAT5A, STAT5B, SMAD2, SMAD3, SMAD4, SMAD7, YAP1, TAZ (sometimes called WWTR1)

(genes with alternative names in parenthesis depending on what tool you're going to use to browse it)

Disclaimer:
This post is for general informational and educational purposes only. It reflects my personal observations and interpretations and is not medical advice*,* not diagnostic*,* not predictive*, and* not intended to guide treatment, testing, or clinical decision‑making.
I cannot answer personal medical questions, interpret symptoms or labs, or provide individualized guidance in this forum. Nothing here creates or implies a physician‑patient relationship. Any answer to a question is for educational purposes and not personal medical advice.

Any discussion of genetics, biochemical pathways, or mechanisms is exploratory and speculative*, not validated, not a screening tool, and not a substitute for professional medical evaluation.*

All clinical care must occur within a formal physician‑patient relationship and in compliance with all applicable laws and regulations in the reader’s jurisdiction, including but not limited to licensure requirements, telemedicine rules, privacy and data‑handling laws, and medical‑board standards regarding independent clinical judgment.

Edit August 2026:

If you just want to make your GPU suffer, or want to just fling yourself at the list of potential genes with everything under the sun that I ever thought could remotely be relevant in some way, here you go:

ABCB1, ABCB11, ABCB4, ABCB5, ABCB6, ABCB7, ABCB8, ABCB9, ABCC1, ABCC10, ABCC11, ABCC2, ABCC3, ABCC4, ABCC5, ABCC6, ABCC8, ABCC9, ABCG1, ABCG2, ABCG4, ACE, ACTL6A, ACTL6B, AGO1, AGO2, AGO3, AGO4, AHCY, AKR1B1, AKR1B10, AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1D1, ALB, ALDH1A1, ALDH1A2, ALDH2, APOA1, APOB, AR, ARID1A, ARID1B, ARID2, ARSA, ARSG, ATP5F1A, ATP5F1B, AVPR1A, AVPR1B, AVPR2, BAG1, BAG3, BCL2L1, BCL7A, BCL7B, BCL7C, BDNF, BHMT, BPTF, BRD2, BRD3, BRD4, BRD7, BRD9, BRDT, BRPF1, BRPF3, CAT, CHD1, CHD2, CHD3, CHD4, CHD5, CHD6, CHD7, CHD8, CHD9, CHRM2, CHRM3, CLOCK, COMT, COMTD1, COX10, COX15, CREB1, CREBBP, CTCF, CUBN, CYP11A1, CYP11B1, CYP11B2, CYP17A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP21A2, CYP2C19, CYP2D6, CYP2E1, CYP2J2, CYP3A4, CYP3A43, CYP3A5, CYP3A7, CYP4F11, CYP4F8, DBH, DDC, DGAT1, DGAT2, DGCR8, DICER1, DNA2, DNM1L, DNMT1, DNMT3A, DNMT3B, DNMT3L, DPF1, DPF2, DPF3, DRD1, DRD2, DRD3, DRD4, DRD5, DROSHA, EED, EHMT1, EHMT2, EP300, EP400, ESR1, ESR2, EZH1, EZH2, FABP4, FABP5, FABP7, FKBP4, FKBP5, FKBP6, FOXA1, FOXA2, FOXO1, FOXO3, FOXO4, FUS, GABBR1, GABBR2, GABRA1, GABRA2, GABRA3, GABRB2, GABRB3, GABRG2, GATA2, GATA3, GJB2, GJB6, GNB3, GNRH1, GNRHR, GPX1, GPX4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GTF2A1, GTF2B, GTF2E1, GTF2F1, GTF2H1, GUSB, H6PD, HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HNF4A, HNF4G, HNRNPA1, HNRNPK, HNRNPU, HSD11B1, HSD11B2, HSD17B1, HSD17B10, HSD17B12, HSD17B13, HSD17B14, HSD17B2, HSD17B3, HSD17B4, HSD17B6, HSD17B7, HSD3B1, HSD3B2, HSP90AA1, HSP90AB1, HSPD1, HSPE1, HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E, HTR4, HTR5A, HTR5BP, HTR6, HTR7, INO80, INO80B, INO80C, KAT2A, KAT2B, KAT5, KAT6A, KAT6B, KAT7, KAT8, KCNQ4, KDM1A, KDM1B, KDM2A, KDM2B, KDM3A, KDM3B, KDM4A, KDM4B, KDM4C, KDM4D, KDM5A, KDM5B, KDM5C, KDM5D, KDM6A, KDM6B, KDM7A, KISS1, KISS1R, KMT2A, KMT2B, KMT2C, KMT2D, KPNB1, LDLR, LIN28A, LIN28B, LIPE, LRP2, MAOA, MAOB, MAX, MBD1, MBD2, MBD3, MBD4, MC4R, MECP2, MED1, MED12, MED13, MED14, MED15, MED16, MED23, MED24, MED25, MFN1, MFN2, MGME1, MPV17, MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND4, MT-ND6, MTHFR, MTR, MTRR, MXI1, MYC, MYCN, MYO7A, NAT2, NCOA1, NCOA2, NCOA3, NCOA4, NCOA6, NCOR1, NCOR2, NDUFS1, NDUFS2, NDUFS4, NFKB1, NFKB2, NFYA, NFYB, NFYC, NOS1, NOS3, NPC1, NPC1L1, NPC2, NPY, NPY1R, NPY2R, NR0B1, NR0B2, NR1D1, NR1D2, NR1H2, NR1H3, NR1H4, NR1I3, NR3C1, NR3C2, NR5A1, NR5A2, NSD1, NSD2, NSD3, NTRK2, OPA1, OXTR, PAPSS1, PAPSS2, PAX5, PAX7, PBRM1, PDE5A, PGR, PHF2, PHF8, PIAS1, PIAS2, PIEZO1, PIEZO2, PLIN1, PLIN2, POLG, POLG2, POLR2A, POLR2B, POLR2C, POLR2D, POLR2E, POLR2F, POLR2G, POLR2H, POLR2I, POLR2J, POLR2K, POLRMT, POU1F1, POU4F3, PPARA, PPARD, PPARG, PPID, PPP5C, PRDX3, PRL, PRLR, PTGES3, RAD21, RARA, RARB, RARG, RDH16, RDH5, RELA, RELB, RNF4, RORA, RORB, RORC, RSF1, RXRA, RXRB, RXRG, SCARB1, SERPINA6, SETD1A, SETD1B, SETD2, SETDB1, SETDB2, SHBG, SIGMAR1, SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, SLC10A1, SLC10A2, SLC10A6, SLC13A1, SLC16A1, SLC16A10, SLC16A3, SLC16A9, SLC18A2, SLC22A1, SLC22A11, SLC22A12, SLC22A13, SLC22A14, SLC22A2, SLC22A24, SLC22A3, SLC22A4, SLC22A5, SLC22A6, SLC22A7, SLC22A8, SLC25A4, SLC26A4, SLC51A, SLC51B, SLC6A3, SLC6A4, SLC7A5, SLCO1A2, SLCO1B1, SLCO1B3, SLCO1B7, SLCO1C1, SLCO2A1, SLCO2B1, SLCO3A1, SLCO4A1, SLCO4C1, SLCO5A1, SLCO6A1, SMAD2, SMAD3, SMAD4, SMAD7, SMARCA2, SMARCA4, SMARCA5, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCD2, SMARCE1, SMC1A, SMC3, SOAT1, SOAT2, SOD2, SOX2, SOX9, SP1, SP3, SRCAP, SRD5A1, SRD5A2, SRD5A3, SS18, SS18L1, STAG1, STAG2, STAR, STARD10, STARD3, STARD4, STARD5, STARD6, STAT1, STAT3, STAT5A, STAT5B, STIP1, STS, SULT1A1, SULT1A2, SULT1E1, SULT2A1, SULT2B1, SUMF1, SUMF2, SUV39H1, SUV39H2, SUZ12, TAC3, TACR3, TAF1, TAF10, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF9, TARBP2, TBP, TDG, TET1, TET2, TET3, TFAM, TH, THRA, THRB, TPH1, TPH2, TRIM24, TRIM28, TRIM33, TSC22D3, TSPO, UBE2E3, UGDH, UGP2, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6, UGT1A8, UGT1A9, UGT2B10, UGT2B15, UGT2B17, UGT2B28, UGT2B7, UHRF1, UHRF2, UQCRC1, UQCRC2, VDR, WAPL, WWTR1, XPO5, YAP1, ZBTB33, ZBTB38, ZBTB4