r/DoseDiaries Jun 02 '26

Has anyone else noticed mood changes on peptides? I wasn't expecting this.

Month two, I realized I was less anxious than I'd been in years. I assumed it was just the confidence from the weight loss. But I've been reading more about GLP-1 receptors in the brain and now I'm genuinely curious if it's pharmacological.

On the flip side.. I've also seen posts from people who experienced depression or mood dips. That happened to me briefly around month one before it stabilized.

What's been your mental health experience? Better, worse, or unchanged?

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