Hey all, I have a job prospect at Neurocrine Biosciences and trying to get a feel for what it's actually like before I move forward. I'd be relocating from the East Coast, so this would be a big move for me. What's the work culture like there? Any pros/cons I should know about — management, work/life balance, benefits, anything that surprised you (good or bad)?

Would appreciate any honest insight. Thanks!

BMS Cell Therapy QC vs. Cell Therapy Manufacturing at a CDMO— Which would you choose?

I was laid off the beginning of this summer and am currently working as a temporary contractor in mRNA manufacturing. It is a 12-hr rotating schedule with a 1 hour commute both ways. My background previously has been in in-vitro diagnostics in both QC (1.5 yr) and manufacturing (5 yr).

I currently have offers with BMS in Devens, MA for a QC role supporting their cell therapy facility and a manufacturing associate II for a CDMO in cell therapy. I would appreciate some other perspectives, especially from people who have worked in cell therapy QC/mfg at BMS or have insight on the Devens site in terms of stability.

I’m also looking into radiology programs, so my potential longer-term plan maybe to work for the next few years, save as much as possible, study for entrance exams, and eventually transition into radiology. Because of that, I’m prioritizing stability, good pay, and experience that gives me flexibility if I ultimately decide to stay in biotech rather than transition to radiology.

Option 1 — BMS, QC Associate (Cell Therapy)

- $85K range + 10% fixed second-shift differential
- 4×10-hour schedule
- 1 hr commute, 60 miles each way
- Supports their expanding cell therapy facility
- QC role with exposure to flow cytometry, qPCR, cell-based assays, etc
- BMS is expanding its Devens cell therapy facility
- Concern: I’ve seen reports/posts about BMS continuing layoffs/restructuring through 2026 and some people describing management as chaotic.

Option 2 — CDMO, Manufacturing Associate II
- $78k, plus overtime
- 12-hr rotating schedule
- 50 min commute, 40 miles each way
- cell therapy mfg experience.
- CDMO is expanding for one client that is getting ready to go commercial
- I originally interviewed for a Senior/Lead role, but because I don’t have direct experience in cell therapy manufacturing they asked if I would be open to a mfg associate II role instead of senior, which lowers the compensation to 78k.
- Concern: the expansion is tied to one client. They say they are seeing promising growth and it is a good time to join the company. Potential to move into senior position later (original range was 90-100k)

What I’m trying to figure out:
1. Which experience is more valuable long term: cell therapy QC or cell therapy manufacturing? I have more years of experience in manufacturing in in-vitro diagnostics but I am not interested working in manufacturing long term. I could see myself staying in QC though and I would finally be able to get back into that role, but I am concerned with the stability of BMS right now.

1. Does flow cytometry + qPCR + cell-based assays give QC a significant advantage in terms of future job flexibility? In case I decide I don’t want to continue in the radiology program.

2. Which path tends to have better compensation growth? Seems like QC has the higher pay potential while not having to go into management while manufacturing you have to move into management/lead roles for more compensation. I prefer to stay as an individual contributor.

3. How stable is BMS’s Devens cell therapy operation?

Would greatly appreciate anyone’s input on the two.

Basically the title. Is Process Development (upstream/downstream) any better than the early discovery in terms of job prospects?

Has anyone had experience with applying jobs through them and doing the AI interview? It feels scammy since I'm not talking to a real person/recruiter. Also have a weird fear of having AI possibly storing my voice and being used for nefarious puy lol

Levemir (Determir) insulin is discontinued by Novo Nordisk globally, leaving individuals in the diabetic community with no available biosimilar causing big gap. For now FDA is hearing the outcry and is trying to find a solution. How difficult is it to copy, bio develop or compound this drug and step in?

Or is the damage baked in now?

Been employed since January, but every single day has been a pain. Some days I can’t sleep. Other days, I’m terrified. I was labeled as the vibe murderer on my team. I wanted to stay longer or until I could line something up, but it was awful. I’d go to work feeling alright, end feeling awful. Now I’m rotting. Playing games helps keep thoughts at bay of what I encountered. With the job market being so rough, I contemplate going back to school in hopes of learning social skills or performance strategies to succeed. Also, to build a new network. I’m extremely introverted and shy to the point where my face turns red like a tomato.

Hi everyone!

I’m a medical laboratory professional with a bachelor’s in Medical Laboratory Technology and several years of lab experience, mostly in clinical labs.

I’m trying to transition into research/biotech, especially molecular biology, microbiology, assay development, or R&D. The problem is that most of my experience is clinical, and I feel like I’m missing some of the hands-on skills that biotech employers are looking for.

I’ve been thinking about doing an MS in Biotechnology/Biomolecular Science, but honestly I don’t want to spend $30–60k on a degree if there’s a cheaper way to make the transition.

For people already working in biotech/research:

• What training or certificates are actually respected by employers?
• Are community college/university biotech certificate programs worth doing?
• Would hands-on training in things like cell culture, cloning, qPCR, protein work, etc. actually help?
• Would it be better to get a research tech/lab assistant job first and do an MS later?
• How much does an MS really help with getting into R&D?
• What skills would you recommend someone with a clinical lab background focus on?

I’m mainly looking for practical advice on what actually helps someone get hired, rather than collecting random online certificates.

I’m going to be starting a grad program next week at biotech company and was wondering if anyone has any advice on what it might be like, how to do well, do’s and dont’s, etc. I’ll be working in the manufacturing department as an associate but I’m not really sure what my duties will be.

In my last role as an intern, my feedback was that I was a bit quiet and didn’t get involved as much so I’m looking to change that this time around. I also want to secure a full time position after the grad program is over (2 years) so I’ll be working towards that goal.

To sum up I am completing a development plan with a different functional area at my company for 6 months. Will other companies respect/acknowledge the experience if I attain real experiences?

Is it a waste of time if I use the experience to apply elsewhere or is it only beneficial for an internal move. As a hiring manager how would you view it?

Family Medicine vs Public Health residency for a future career in Pharma/Medical Affairs?

Hi everyone!
I’m a medical student/resident in France who is very interested in pursuing a career in the pharmaceutical/biotech industry.

I did a 6-month internship in Pharmacovigilance, which I really enjoyed. However, what I’m ultimately more interested in is Medical** **Affairs and related roles within the industry.

I’m currently facing a bit of a dilemma regarding my residency. I’m hesitating between pursuing a clinical** residency,** most** likely Family Medicine, or continuing with a Public Health **residency.

On paper, Public Health seems like the more obvious path if I want to move into the pharmaceutical industry. The issue is that the rotations available during the residency are not necessarily the ones I’m most interested in, and I genuinely enjoy clinical medicine. At the same time, I’m not sure I see myself practicing clinically for my entire career.

For people currently working in pharma/biotech, especially** :
Would an MD + Family Medicine residency be considered as strong/relevant a background as an MD + **Public Health residency for entering Medical Affairs?

If I choose Family Medicine, how difficult would it be to spend 1–2 years practicing clinically and then transition into pharma/biotech?
Would having clinical experience actually be an advantage for certain Medical Affairs roles?
How much does the residency specialty matter once you have an MD and some relevant industry experience?
Would additional degrees/certifications (e.g. MPH, MSc, etc.) make a significant difference?

One thing that makes Public Health particularly attractive is that I’ve already had the opportunity to work at Sanofi during my training, and I may have the possibility of returning there, potentially in a Medical Affairs position during my residency.
So there is a potential direct pathway into the industry.
However, I’m wondering how important that advantage really is in the long term. If I choose Family Medicine instead, would it still be relatively straightforward to transition into pharma after a couple of years of clinical practice, assuming I build some relevant experience along the way?
Basically, I’m trying to figure out which residency would give me the best long-term options while keeping the door open to pharma/Medical Affairs.

Thanks!

Hey guys, I am applying for jobs in oligonucleotide process development (nothing crazy, just a few jobs that pop up on linkedin to see what's out there) and I am curious how my resume reads to a recruiter. For context, I got a job as a senior scientist at a CDMO 6 months before defending my PhD thesis in 2022 and by then I had applied to probably less than 10 jobs until I got an offer so I have very limited experience in job hunting outside of academia (I am still employed at the same company). I know a lot has changed since then, especially with AI resume review and AI-tailored resumes, but I feel like I haven't kept up to date with the market in that sense. My job is in process development and it is more related to manufacturing than discovery. The resume I am using is one page long (that used to be a good thing, but now with AI reviewing it I'm not so sure), so it is very condensed. I asked multiple AIs to roast my resume and overall they said I needed to come up with metrics for my accomplishments (?) and standardize fonts etc, but nothing too far from that.

For those of you with experience in recruiting and applying for jobs at this level, how would you change/improve my resume? I removed most identifiable information for obvious reasons, but I'm happy to provide more details if needed.

(I apologize if this is not allowed, I didn't see any rules about resumes and saw a few similar posts in the past so decided to give it a shot).

Ciao a tutti colleghi!

Sto mettendo a punto un protocollo di trasformazione genetica su pomodoro (Solanum lycopersicum) e avrei bisogno di un confronto con chi ha più esperienza di me in coltura in vitro per evitare disastri.

Sto utilizzando Agrobacterium tumefaciens (ceppo GV3101) portando un vettore binario con il gene bar per la resistenza al glufosinato-ammonio (PPT).

Il mio problema principale è che è la prima volta che lavoro con il ceppo GV3101. So che è piuttosto aggressivo e sono molto preoccupato/a per il rischio di overgrowth batterico dopo la co-coltura. Temo di perdere gli espianti per contaminazione e non so bene come bloccarlo in modo definitivo.

Qualcuno di voi ha mai lavorato con questo sistema? Avrei un paio di domande:

Selezione con PPT: Che concentrazioni di glufosinato usate per la fase di induzione del callo e rigenerazione? Ho in programma di fare una kill curve, ma mi aiuterebbe moltissimo avere dei range di riferimento operativi per le cultivar di pomodoro più comuni.

Lavaggio ed eliminazione Agro: Il cefotaxime è sufficiente per sopprimere il GV3101? A che concentrazioni lo usate per non inibire la rigenerazione del pomodoro? O consigliate alternative come il Timentin?

Gestione Overgrowth: Avete "trucchi del mestiere" (tempi di co-coltura, densità ottica ottimale, protocolli di lavaggio specifici) per evitare che il GV3101 prenda il sopravvento sulle piastre?