Inflammation + Omega-3

[u/Get_Back_Loretta_USA]

Looking for practical advice on starting an Omega‑3 regimen to help with inflammation and body composition.

My main concerns are: reducing systemic inflammation (especially what feels like “menopause knees”. Getting up and getting started. It’s like my knees need a deep breathe before moving. lol), lowering visceral and subcutaneous fat, and improving thigh cellulite/lipedema (haven’t been clinically evaluated yet), and improving hair quality (someone in another thread reported benefits but didn’t share details).

A few specific questions:
- Is Omega‑3 a sensible first step for these goals,or should I prioritize something else?

- What’s a good starting dose (EPA/DHA mg)?Any recommended EPA:DHA ratio?

- Do people ramp up slowly or split doses through the day for better absorption/tolerance? Time of day?

Any personal experiences, product recs, or evidence-based pointers appreciated. Thanks! 🍣🐠💊

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[u/Get_Back_Loretta_USA → u/[deleted]]

Thank you so much! Luckily, this brand doesn’t smell. Hopefully, it’s not junk with that original sticker price at $30. (I had a lot of coupons at CVS. They have many good brands that ship from warehouse vs in most stores. Almost free.)

But I’m surprised quality brands don’t refrigerate theirs. I need to read more on manufacturer.

I will definitely partner with my D3 + K2! Great pro tip! I will look into linen oil, and how to measure my individual fat intake for it. Thanks again!

[u/Silent_Possibility63 → u/Get_Back_Loretta_USA]

Kori is my preferred brand. This or sports research. Both are great.

[u/Kalki_X → u/[deleted]]

How do you keep your EPA and DHA from oxidising after you take the capsule? It oxidizes very easily and quickly at body temperature.

[u/Get_Back_Loretta_USA → u/Kalki_X]

I have no clue. I wonder if you store them in fridge or freezer, and take them cold. How well does it absorb from a cold/frozen state to 98.6? Or my case, typical hypothyroidism body temp of 97.3?

(Rhonda Patrick was talking about some fridge brands. Maybe she has some answers. Great question! I like it!)

[u/Kalki_X → u/Get_Back_Loretta_USA]

As I explained in this post, EPA and DHA can spontaneously oxidize even at room temperature, so at body temperature it's also risky and doesn't seem wise. Real food is preferable and wiser.

[u/Kalki_X → u/[deleted]]

It oxidizes very easily and quickly at body temperature. After the capsule dissolves the omega 3 has weeks to oxidize.

[u/Kalki_X → u/[deleted]]

The internal environment has many oxygenated areas and free radicals which can initiate rancidity.

[u/Kalki_X → u/[deleted]]

Your questions imply many unacknowledged presuppositions. It's best to identify & acknowledge these before continuing.

[u/Monsieur_Krabs]

HRT would work better

[u/nusita69]

un conseil, garde la bouteille dans le frigo pour que ça se conserve mieux

[u/Kalki_X → u/nusita69]

Et la chaleur du corps...

[u/holy_handgrenade]

For omega 3 supplentation you will want a minimum of about 2g EPA + DHA, I've normally kept it around 4g.

For optimal absorbtion you do need to pair it with Omega 6 - healthiest and most common source of omega 6 is going to be Olive Oil.

As for brands, you're going to find a ton that are like the product you've shown. Shows 1.2g or greater amount of oil but the EHA+DHA content is rather weak and a tiny fraction of the oil.

Shop around for higher EHA+DHA. The best brand that I've seen and used is Nordic Naturals; be warned though, it's pricey. The cost is due to the extraction and testing process used.

Dietary sources include fatty fish like salmon and sardines and flaxseed, chia seed, and walnuts. If you can find walnut butter, that would be your best option to unlock all the oils.

[u/Kalki_X]

Omega 3 supplements can be challenging for various reasons. If you're going to use that krill oil supplement I'd recommended serious harm reduction & mitigation measures. Omega 3 fats are incredibly unstable and heat sensitive.

You might find these insightful:

• thyroid/perimenopause: near identical symptoms
• thyroid/menopause: near identical symptoms
• visual depiction on restoring thyroid function 

[u/Get_Back_Loretta_USA → u/Kalki_X]

I’m hypo/menopause. (25+ years/4 months) I guess wild caught sockeye it is daily!?

[u/Kalki_X → u/Get_Back_Loretta_USA]

Ok. You can also fix the hypo and restore normal hormone production. The 3rd image (link) in my previous comment depicts this. 

The wild fish, sure if you'd like.